(Q40750080)

23 September 2017

Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis (English)

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23 September 2017

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Tanya M Gottlieb

1

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23 September 2017

Juan Fernando Martinez Leal

2

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23 September 2017

Rony Seger

3

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23 September 2017

Yoichi Taya

4

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23 September 2017

Moshe Oren

5

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23 September 2017

language of work or name

English

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publication date

1 February 2002

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23 September 2017

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23 September 2017

21

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23 September 2017

1299-1303

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23 September 2017

8

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205181

23 September 2017

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cites work

p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

The cleavage of Akt/protein kinase B by death receptor signaling is an important event in detachment-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Mapping of the p53 and mdm-2 interaction domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Cellular survival: a play in three Akts

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Oncogene-dependent regulation of caspase activation by p53 protein in a cell-free system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Functions of the MDM2 oncoprotein

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

p53 facilitates pRb cleavage in IL-3-deprived cells: novel pro-apoptotic activity of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

p53 in growth control and neoplasia

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

DNA double-strand breaks: signaling, repair and the cancer connection

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Activation of the phosphatidylinositol 3-kinase/Akt pathway protects against interleukin-3 starvation but not DNA damage-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Nuclear and mitochondrial apoptotic pathways of p53.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

MDM2--master regulator of the p53 tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Peptide and protein library screening defines optimal substrate motifs for AKT/PKB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Regulation of the p53 tumor suppressor protein

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Activation of an MDM2-specific caspase by p53 in the absence of apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Defying death after DNA damage.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Phosphoinositide 3-OH kinase (PI3K) and PKB/Akt delay the onset of p53-mediated, transcriptionally dependent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Protein kinases: six degrees of separation?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

1 reference

7 January 2021

Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205181

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205181

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Dimensions Publication ID

23 September 2017

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