(Q39970146)

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Inadequate activation of the GTPase RhoA contributes to the lack of fibronectin matrix assembly in von Hippel-Lindau protein-defective renal cancer cells

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1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Inadequate activation of the GTPase RhoA contributes to the lack of fibronectin matrix assembly in von Hippel-Lindau protein-defective renal cancer cells (English)

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Miguel A Esteban

4

object named as

Miguel A Esteban

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

author name string

Monica Feijóo-Cuaresma

1

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Fernando Méndez

2

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Alfredo Maqueda

3

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Salvador Naranjo-Suarez

5

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Maria C Castellanos

6

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Mercedes Hernández del Cerro

7

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Silvia N Vazquez

8

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Angeles García-Pardo

9

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Manuel O Landázuri

10

1 reference

Europe PubMed Central

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16 September 2017

Maria J Calzada

11

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Europe PubMed Central

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16 September 2017

language of work or name

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publication date

19 June 2008

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Europe PubMed Central

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16 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

16 September 2017

283

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

36

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

24982-24990

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-kappaB agonist Card9 by CK2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

The von Hippel-Lindau tumour suppressor interacts with microtubules through kinesin-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Interaction of hydroxylated collagen IV with the von hippel-lindau tumor suppressor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Formation of primary cilia in the renal epithelium is regulated by the von Hippel-Lindau tumor suppressor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

p53 stabilization and transactivation by a von Hippel-Lindau protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

pVHL function is essential for endothelial extracellular matrix deposition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Endocytic function of von Hippel-Lindau tumor suppressor protein regulates surface localization of fibroblast growth factor receptor 1 and cell motility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

von Hippel-Lindau tumor suppressor protein regulates the assembly of intercellular junctions in renal cancer cells through hypoxia-inducible factor-independent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Characterization of a von Hippel Lindau pathway involved in extracellular matrix remodeling, cell invasion, and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Ectopic expression of von Hippel-Lindau tumor suppressor induces apoptosis in 786-O renal cell carcinoma cells and regresses tumor growth of 786-O cells in nude mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

pVHL modification by NEDD8 is required for fibronectin matrix assembly and suppression of tumor development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Alpha4beta1 integrin/ligand interaction inhibits alpha5beta1-induced stress fibers and focal adhesions via down-regulation of RhoA and induces melanoma cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

The ins and outs of fibronectin matrix assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Protein Kinase Cα-Induced p115RhoGEF Phosphorylation Signals Endothelial Cytoskeletal Rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

RhoGTPases and Their Role in Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Gene expression profiling in a renal cell carcinoma cell line: dissecting VHL and hypoxia-dependent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Molecular basis of the VHL hereditary cancer syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

VHL-mediated hypoxia regulation of cyclin D1 in renal carcinoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Rho family proteins: coordinating cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Contrasting effects on HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

VHL induces renal cell differentiation and growth arrest through integration of cell-cell and cell-extracellular matrix signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Integrin dynamics and matrix assembly: tensin-dependent translocation of alpha(5)beta(1) integrins promotes early fibronectin fibrillogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Synthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

The von Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasion and branching morphogenesis in renal carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Rho-mediated contractility exposes a cryptic site in fibronectin and induces fibronectin matrix assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Lysophosphatidic acid and microtubule-destabilizing agents stimulate fibronectin matrix assembly through Rho-dependent actin stress fiber formation and cell contraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Altered rate of fibronectin matrix assembly by deletion of the first type III repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

Integrins: versatility, modulation, and signaling in cell adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

22 September 2017

RhoA activity is required for fibronectin assembly and counteracts beta1B integrin inhibitory effect in FRT epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

25 September 2017

Tumour suppression by the human von Hippel-Lindau gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

25 September 2017

PKCdelta regulates endothelial basal barrier function through modulation of RhoA GTPase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

17 June 2018

Down-regulation of hypoxia-inducible factor-2 in PC12 cells by nerve growth factor stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

17 June 2018

The von Hippel-Lindau tumour-suppressor protein interaction with protein kinase Cdelta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

20 August 2018

Regulation of E-cadherin expression by VHL and hypoxia-inducible factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

20 August 2018

Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

20 August 2018

Direct association of RhoA with specific domains of PKC-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

20 August 2018

Fibronectin is a hypoxia-independent target of the tumor suppressor VHL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

20 August 2018

Role of nuclear and cytoplasmic localization in the tumour-suppressor activity of the von Hippel-Lindau protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

20 August 2018

Role of the von Hippel-Lindau tumor suppressor gene in the formation of beta1-integrin fibrillar adhesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

20 August 2018

Protein kinase C-alpha signals rho-guanine nucleotide dissociation inhibitor phosphorylation and rho activation and regulates the endothelial cell barrier function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529126

20 August 2018

Expression of fibronectin and HIF-1alpha in renal cell carcinomas: relationship to von Hippel-Lindau gene inactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18567581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The von Hippel-Lindau gene product inhibits vascular permeability factor/vascular endothelial growth factor expression in renal cell carcinoma by blocking protein kinase C pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/18567581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

von Hippel-Lindau disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18567581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Collagen matrix assembly is driven by the interaction of von Hippel-Lindau tumor suppressor protein with hydroxylated collagen IV alpha 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/18567581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/18567581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

von Hippel-Lindau protein promotes the assembly of actin and vinculin and inhibits cell motility

1 reference

https://pubmed.ncbi.nlm.nih.gov/18567581

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M709390200

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

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