(Q39972651)

16 September 2017

Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L. (English)

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16 September 2017

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I Papandreou

1

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16 September 2017

A L Lim

series ordinal

2

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16 September 2017

K Laderoute

series ordinal

3

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16 September 2017

N C Denko

series ordinal

4

1 reference

16 September 2017

13 June 2008

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Cell Death & Differentiation

16 September 2017

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16 September 2017

15

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16 September 2017

1572-1581

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16 September 2017

10

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https://scigraph.springernature.com/pub.10.1038/cdd.2008.84

16 September 2017

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cites work

Hypoxia in cancer: significance and impact on clinical outcome

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Hypoxic heterogeneity in human tumors: EF5 binding, vasculature, necrosis, and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Loss of Mcl-1 protein and inhibition of electron transport chain together induce anoxic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Anoxia-induced apoptosis occurs through a mitochondria-dependent pathway in lung epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Hypoxia-induced energy stress regulates mRNA translation and cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

AMP-activated Protein Kinase and the Regulation of Autophagic Proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Self-eating and self-killing: crosstalk between autophagy and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Autophagy: from phenomenology to molecular understanding in less than a decade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

A protein conjugation system essential for autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Induction of autophagy and inhibition of tumorigenesis by beclin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Autophagy suppresses tumor progression by limiting chromosomal instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Methods for monitoring autophagy from yeast to human

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Selective silencing of the hypoxia-inducible factor 1 target gene BNIP3 by histone deacetylation and methylation in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Endoplasmic reticulum stress: a new pathway to induce autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Generation of cell lines with tetracycline-regulated autophagy and a role for autophagy in controlling cell size.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Apg5p functions in the sequestration step in the cytoplasm-to-vacuole targeting and macroautophagy pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Why do cancers have high aerobic glycolysis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

The response of c-jun/AP-1 to chronic hypoxia is hypoxia-inducible factor 1 alpha dependent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

Anoxia is necessary for tumor cell toxicity caused by a low-oxygen environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.84

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/CDD.2008.84

1 reference

16 September 2017

1 reference