(Q35155445)

6 August 2017

title

Hypoxia-induced energy stress regulates mRNA translation and cell growth (English)

1 reference

6 August 2017

0 references

1 reference

5

Craig B Thompson

1 reference

6 August 2017

Liping Liu

1

1 reference

6 August 2017

Timothy P Cash

2

1 reference

6 August 2017

Russell G Jones

3

1 reference

6 August 2017

Brian Keith

4

1 reference

6 August 2017

M Celeste Simon

6

1 reference

6 August 2017

language of work or name

1 reference

1 February 2006

1 reference

6 August 2017

1 reference

6 August 2017

volume

21

1 reference

6 August 2017

issue

4

1 reference

6 August 2017

page(s)

521-531

1 reference

Control of the hypoxic response through regulation of mRNA translation.

6 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

28 July 2018

1 reference

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Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis

28 July 2018

1 reference

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mTOR, translational control and human disease.

28 July 2018

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The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway

28 July 2018

1 reference

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REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase.

28 July 2018

1 reference

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Lessons from the Eker rat model: from cage to bedside

28 July 2018

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The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila

28 July 2018

1 reference

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Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity

28 July 2018

1 reference

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Activating transcription factor 4 is translationally regulated by hypoxic stress

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

Regulation of transcription and translation by hypoxia

28 July 2018

1 reference

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TSC2: filling the GAP in the mTOR signaling pathway

28 July 2018

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The AMP-activated protein kinase cascade--a unifying system for energy control

28 July 2018

1 reference

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Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398

28 July 2018

1 reference

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mTOR as a Positive Regulator of Tumor Cell Responses to Hypoxia

28 July 2018

1 reference

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Management of cellular energy by the AMP-activated protein kinase system

28 July 2018

1 reference

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A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets.

28 July 2018

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Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

Initiation factor eIF2 alpha phosphorylation in stress responses and apoptosis.

28 July 2018

1 reference

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A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

TOR, a central controller of cell growth

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

Rodent model of reproductive tract leiomyomata. Establishment and characterization of tumor-derived cell lines.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

TSC2 mediates cellular energy response to control cell growth and survival

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

Rheb fills a GAP between TSC and TOR.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

Tuberous sclerosis: from tubers to mTOR.

27 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

Biochemical correlates of mTOR inhibition by the rapamycin ester CCI-779 and tumor growth inhibition

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

Regulation of proliferation-survival decisions during tumor cell hypoxia

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153113

Regulation of protein synthesis in human cells exposed to extreme hypoxia

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16483933

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Insulinotropic action of methyl pyruvate: enzymatic and metabolic aspects

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16483933

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Transcription inhibitors stimulate translation of 5' TOP mRNAs through activation of S6 kinase and the mTOR/FRAP signalling pathway

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16483933

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2006.01.010

1 reference

6 August 2017

1 reference

6 August 2017

1 reference