(Q39975711)

16 September 2017

title

Kinetic imaging of NPC1L1 and sterol trafficking between plasma membrane and recycling endosomes in hepatoma cells (English)

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16 September 2017

main subject

hepatocellular carcinoma

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Daniel Wüstner

4

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author name string

Nicole Hartwig Petersen

series ordinal

1

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16 September 2017

Nils J Faergeman

series ordinal

2

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16 September 2017

Liqing Yu

series ordinal

3

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16 September 2017

publication date

3 June 2008

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Journal of Lipid Research

16 September 2017

published in

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16 September 2017

volume

49

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16 September 2017

issue

9

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16 September 2017

page(s)

2023-2037

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Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption

16 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)

21 January 2018

1 reference

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Zetia: inhibition of Niemann-Pick C1 Like 1 (NPC1L1) to reduce intestinal cholesterol absorption and treat hyperlipidemia

21 January 2018

1 reference

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Cholesterol-regulated translocation of NPC1L1 to the cell surface facilitates free cholesterol uptake

21 January 2018

1 reference

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Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe

21 January 2018

1 reference

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Class B type I scavenger receptor is responsible for the high affinity cholesterol binding activity of intestinal brush border membrane vesicles

21 January 2018

1 reference

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Niemann-Pick C1-like 1 overexpression facilitates ezetimibe-sensitive cholesterol and beta-sitosterol uptake in CaCo-2 cells.

21 January 2018

1 reference

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Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis

21 January 2018

1 reference

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The role of the Niemann-Pick C1-like 1 protein in the subcellular transport of multiple lipids and their homeostasis

21 January 2018

1 reference

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Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia.

21 January 2018

1 reference

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Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosome

21 January 2018

1 reference

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Fusion accessibility of endocytic compartments along the recycling and lysosomal endocytic pathways in intact cells

21 January 2018

1 reference

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Evidence for nonvectorial, retrograde transferrin trafficking in the early endosomes of HEp2 cells.

21 January 2018

1 reference

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Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process

21 January 2018

1 reference

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Microtubule-disrupting drugs blocked delivery of endocytosed transferrin to the cytocenter, but did not affect return of transferrin to plasma membrane

21 January 2018

1 reference

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Transferrin recycling and dextran transport to lysosomes is differentially affected by bafilomycin, nocodazole, and low temperature.

21 January 2018

1 reference

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(Glyco)sphingolipids are sorted in sub-apical compartments in HepG2 cells: a role for non-Golgi-related intracellular sites in the polarized distribution of (glyco)sphingolipids

21 January 2018

1 reference

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Vesicular and nonvesicular transport of phosphatidylcholine in polarized HepG2 cells.

21 January 2018

1 reference

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The receptor recycling pathway contains two distinct populations of early endosomes with different sorting functions

21 January 2018

1 reference

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Quantification of polarized trafficking of transferrin and comparison with bulk membrane transport in hepatic cells

21 January 2018

1 reference

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NPC1L1 (Niemann-Pick C1-like 1) mediates sterol-specific unidirectional transport of non-esterified cholesterol in McArdle-RH7777 hepatoma cells

21 January 2018

1 reference

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Acute cholesterol depletion inhibits clathrin-coated pit budding

21 January 2018

1 reference

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Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

Segregation of glucosylceramide and sphingomyelin occurs in the apical to basolateral transcytotic route in HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

Rapid nonvesicular transport of sterol between the plasma membrane domains of polarized hepatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

Aminophospholipids have no access to the luminal side of the biliary canaliculus: implications for thr specific lipid composition of the bile fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

Different transport routes for high density lipoprotein and its associated free sterol in polarized hepatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

Polarized sphingolipid transport from the subapical compartment: evidence for distinct sphingolipid domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

Improved visualization and quantitative analysis of fluorescent membrane sterol in polarized hepatic cells.

21 January 2018

1 reference

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Vesicular and non-vesicular sterol transport in living cells. The endocytic recycling compartment is a major sterol storage organelle

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

Direct observation of rapid internalization and intracellular transport of sterol by macrophage foam cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

Segregation of transferrin to a mildly acidic (pH 6.5) para-Golgi compartment in the recycling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

Mathematical analysis of hepatic high density lipoprotein transport based on quantitative imaging data

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

Endocytic sorting of lipid analogues differing solely in the chemistry of their hydrophobic tails.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

Plasma membrane sterol distribution resembles the surface topography of living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

Quantitative ER <--> Golgi transport kinetics and protein separation upon Golgi exit revealed by vesicular integral membrane protein 36 dynamics in live cells

21 January 2018

1 reference

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21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

The recycling endosome of Madin-Darby canine kidney cells is a mildly acidic compartment rich in raft components

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

Evidence for a Niemann-pick C (NPC) gene family: identification and characterization of NPC1L1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

Signals for sorting of transmembrane proteins to endosomes and lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

Cholesterol-dependent retention of GPI-anchored proteins in endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

The sterol-sensing domain of the Niemann-Pick C1 (NPC1) protein regulates trafficking of low density lipoprotein cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

Polarized sphingolipid transport from the subapical compartment changes during cell polarity development

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

The subapical compartment: a traffic center in membrane polarity development

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

The ABCA1 transporter functions on the basolateral surface of hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

Localization and role of NPC1L1 in cholesterol absorption in human intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800145-JLR200

10.1194/JLR.M800145-JLR200

21 January 2018

Identifiers

DOI

1 reference

16 September 2017

1 reference