Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q39981678)
Watch
English
A dual role of p21waf1/cip1 gene in apoptosis of HEp-2 treated with cisplatin or methotrexate.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
18483502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18483502%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
title
A dual role of p21waf1/cip1 gene in apoptosis of HEp-2 treated with cisplatin or methotrexate
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
18483502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18483502%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
main subject
apoptotic process
0 references
cisplatin
1 reference
based on heuristic
inferred from title
author
Sandra Kraljević Pavelić
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
18483502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18483502%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
author name string
T Cacev
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
18483502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18483502%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
M Kralj
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
18483502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18483502%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
publication date
16 May 2008
1 reference
stated in
Europe PubMed Central
PubMed ID
18483502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18483502%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
published in
Cancer Gene Therapy
1 reference
stated in
Europe PubMed Central
PubMed ID
18483502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18483502%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
volume
15
1 reference
stated in
Europe PubMed Central
PubMed ID
18483502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18483502%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
issue
9
1 reference
stated in
Europe PubMed Central
PubMed ID
18483502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18483502%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
page(s)
576-590
1 reference
stated in
Europe PubMed Central
PubMed ID
18483502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18483502%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/cgt.2008.28
0 references
cites work
CD95/Fas signaling in T lymphocytes induces the cell cycle control protein p21cip-1/WAF-1, which promotes apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
21 January 2018
Dipyridamole increases the cytotoxicity of cisplatin in human larynx cancer cells in vitro.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
21 January 2018
In vitro growth suppression by adenoviral transduction of p21 and p16 in squamous cell carcinoma of the head and neck: a research model for combination gene therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
21 January 2018
Molecular action of methotrexate in inflammatory diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
21 January 2018
Defects in G1-S cell cycle control in head and neck cancer: a review
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic functions of tumour suppressor p21(Waf1/Cip1/Sdi1): association with cell senescence and tumour-promoting activities of stromal fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential effects of cell cycle regulatory protein p21(WAF1/Cip1) on apoptosis and sensitivity to cancer chemotherapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21Waf1/Cip1 as a therapeutic target in breast and other cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance to Fas-mediated apoptosis: activation of caspase 3 is regulated by cell cycle regulator p21WAF1 and IAP gene family ILP
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: implications for carcinogenesis, senescence, and age-related diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endogenous p21WAF1/CIP1 status predicts the response of human tumor cells to wild-type p53 and p21WAF1/CIP1 overexpression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The novel pyrimidine and purine derivatives of l-ascorbic acid: synthesis, one- and two-dimensional 1H and 13C NMR study, cytostatic and antiviral evaluation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new mathematical model for relative quantification in real-time RT-PCR
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Introduction of p21(Waf1/Cip1) gene into a carcinoma cell line of the uterine cervix with inactivated p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overview of cell death signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The therapeutic potential of 4-1BB (CD137) in cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of TNF receptor-associated factor 2 and p38 mitogen-activated protein kinase activation during 4-1BB-dependent immune response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human 4-1BB (CD137) signals are mediated by TRAF2 and activate nuclear factor-kappa B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Life in the balance: how BH3-only proteins induce apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gadd45a, a p53- and BRCA1-regulated stress protein, in cellular response to DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of differential protein expression by cisplatin treatment in cervical carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of mammary carcinoma growth in vitro and in vivo by inducible expression of the Cdk inhibitor p21.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of p21WAF1 sensitizes cells to apoptosis via an increase of both p14ARF and p53 levels and an alteration of the Bax/Bcl-2 ratio.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exogenous expression of p21(WAF1/CIP1) exerts cell growth inhibition and enhances sensitivity to cisplatin in hepatoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cyclin-dependent kinase inhibitor p21(cip1/waf1) enhances the cytotoxicity of ganciclovir in HSV-tk transfected ovarian carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The central region of Gadd45 is required for its interaction with p21/WAF1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase 3-mediated cleavage of p21WAF1/CIP1 associated with the cyclin A-cyclin-dependent kinase 2 complex is a prerequisite for apoptosis in SK-HEP-1 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gadd45alpha does not modulate the carboplatin or 5-fluorouracil-induced apoptosis in human papillomavirus-positive cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Late activation of stress kinases (SAPK/JNK) by genotoxins requires the DNA repair proteins DNA-PKcs and CSB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gadd45a expression induces Bim dissociation from the cytoskeleton and translocation to mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCGT.2008.28
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/CGT.2008.28
1 reference
stated in
Europe PubMed Central
PubMed ID
18483502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18483502%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
PubMed ID
18483502
1 reference
stated in
Europe PubMed Central
PubMed ID
18483502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18483502%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
ResearchGate publication ID
5366098
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
