(Q39992958)

16 September 2017

title

The role of oxidative stress in acrolein-induced DNA damage in HepG2 cells (English)

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16 September 2017

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Longjie Li

1

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16 September 2017

Liping Jiang

2

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16 September 2017

Chengyan Geng

3

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16 September 2017

Jun Cao

4

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16 September 2017

Laifu Zhong

5

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16 September 2017

publication date

1 April 2008

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16 September 2017

published in

Free Radical Research

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16 September 2017

volume

42

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16 September 2017

issue

4

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16 September 2017

page(s)

354-361

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Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

16 September 2017

cites work

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Aldehyde sources, metabolism, molecular toxicity mechanisms, and possible effects on human health

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Acrolein produced from polyamines as one of the uraemic toxins

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Acrolein is a product of lipid peroxidation reaction. Formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins

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Naturally occurring carbonyl compounds are mutagens in Salmonella tester strain TA104.

21 January 2018

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Thiol status and cytopathological effects of acrolein in normal and xeroderma pigmentosum skin fibroblasts

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Use of human-derived liver cell lines for the detection of environmental and dietary genotoxicants; current state of knowledge

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The molecular effects of acrolein

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Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease.

21 January 2018

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4-Hydroxy-2-nonenal: a product and mediator of oxidative stress

21 January 2018

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Acrolein-induced cell death in PC12 cells: role of mitochondria-mediated oxidative stress.

21 January 2018

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Acrolein-induced cytotoxicity in cultured human bronchial epithelial cells. Modulation by alpha-tocopherol and ascorbic acid

21 January 2018

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Induction of thioredoxin reductase as an adaptive response to acrolein in human umbilical vein endothelial cells

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Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing

21 January 2018

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Analysis of a form of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis

21 January 2018

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Analysis of chromate-induced DNA-protein crosslinks with the comet assay

21 January 2018

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Protective effects of panduratin A against oxidative damage of tert-butylhydroperoxide in human HepG2 cells

21 January 2018

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

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Cigarette smoke induces direct DNA damage in the human B-lymphoid cell line Raji

21 January 2018

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Formation of inter- and intrastrand imine type DNA-DNA cross-links through secondary reactions of aldehydic adducts

21 January 2018

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Genotoxicity of singlet oxygen

21 January 2018

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Current status of acrolein as a lipid peroxidation product

21 January 2018

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Mitochondrial free radical generation, oxidative stress, and aging

21 January 2018

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Acrolein induces oxidative stress in brain mitochondria

21 January 2018

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The influence of glutathione and detoxifying enzymes on DNA damage induced by 2-alkenals in primary rat hepatocytes and human lymphoblastoid cells

21 January 2018

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Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?

21 January 2018

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Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted G.C-->T.A transversions in simian kidney cells

21 January 2018

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1,N2-deoxyguanosine adducts of acrolein, crotonaldehyde, and trans-4-hydroxynonenal cross-link to peptides via Schiff base linkage

21 January 2018

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Acrolein-induced oxygen radical formation

21 January 2018

1 reference

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Application of an immunoassay for cyclic acrolein deoxyguanosine adducts to assess their formation in DNA of Salmonella typhimurium under conditions of mutation induction by acrolein.

21 January 2018

1 reference

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Formation of cyclic deoxyguanosine adducts in Chinese hamster ovary cells by acrolein and crotonaldehyde

21 January 2018

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Detection of exocyclic 1,N2-propanodeoxyguanosine adducts as common DNA lesions in rodents and humans

21 January 2018

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Mutagenic activity of acrolein in S. typhimurium and E. coli.

21 January 2018

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Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair

21 January 2018

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10.1080/10715760802008114

21 January 2018

Identifiers

DOI

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16 September 2017

1 reference