(Q39995396)

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The G604S-hERG mutation alters the biophysical properties and exerts a dominant-negative effect on expression of hERG channels in HEK293 cells

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

The G604S-hERG mutation alters the biophysical properties and exerts a dominant-negative effect on expression of hERG channels in HEK293 cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

author name string

Jianhua Huo

1

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Yanmin Zhang

2

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Na Huang

3

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Ping Liu

4

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Chen Huang

5

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Xueyan Guo

6

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Wenhui Jiang

7

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Nan Zhou

8

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Andrew Grace

9

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Christopher L H Huang

10

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Aiqun Ma

11

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

publication date

3 April 2008

1 reference

Europe PubMed Central

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16 September 2017

Pfluegers Archiv

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

456

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

917-928

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0454-0

21 January 2018

Novel mechanism of HERG current suppression in LQT2: shift in voltage dependence of HERG inactivation.

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0454-0

21 January 2018

Increased risk of arrhythmic events in long-QT syndrome with mutations in the pore region of the human ether-a-go-go-related gene potassium channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

hERG potassium channels and cardiac arrhythmia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological rescue of trafficking defective HERG channels formed by coassembly of wild-type and long QT mutant N470D subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel KCNQ1 and HERG missense mutations in Dutch long-QT families

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac causes of sudden unexpected death in children and their relationship to seizures and syncope: genetic testing for cardiac electropathies

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allosteric effects of mutations in the extracellular S5-P loop on the gating and ion permeation properties of the hERG potassium channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel mutation (T65P) in the PAS domain of the human potassium channel HERG results in the long QT syndrome by trafficking deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long QT syndrome: cellular basis and arrhythmia mechanism in LQT2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective assembly and trafficking of mutant HERG channels with C-terminal truncations in long QT syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic testing in the long QT syndrome: development and validation of an efficient approach to genotyping in clinical practice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of I(Kr) inactivation by mutation N588K in KCNH2: a link to arrhythmogenesis in short QT syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and functional characterization of common polymorphisms in HERG (KCNH2) potassium channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A missense mutation (G604S) in the S5/pore region of HERG causes long QT syndrome in a Chinese family with a high incidence of sudden unexpected death

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective protein trafficking in hERG-associated hereditary long QT syndrome (LQT2): molecular mechanisms and restoration of intracellular protein processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel mutation in the Per-Arnt-Sim domain of KCNH2 causes a malignant form of long-QT syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The HERG K+ channel: progress in understanding the molecular basis of its unusual gating kinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retention in the endoplasmic reticulum as a mechanism of dominant-negative current suppression in human long QT syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The N588K-HERG K+ channel mutation in the 'short QT syndrome': mechanism of gain-in-function determined at 37 degrees C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

I(Kr): the hERG channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/18386051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00424-008-0454-0

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

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