(Q40568661)

21 September 2017

title

Pharmacological rescue of trafficking defective HERG channels formed by coassembly of wild-type and long QT mutant N470D subunits (English)

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21 September 2017

Qiuming Gong

1

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21 September 2017

Corey L Anderson

series ordinal

2

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21 September 2017

Craig T January

series ordinal

3

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21 September 2017

Zhengfeng Zhou

series ordinal

4

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21 September 2017

publication date

8 April 2004

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American Journal of Physiology Heart and Circulatory Physiology

21 September 2017

published in

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21 September 2017

volume

287

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21 September 2017

issue

2

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21 September 2017

page(s)

H652-8

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Traffic jam: a compendium of human diseases that affect intracellular transport processes

21 September 2017

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A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

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Retention in the endoplasmic reticulum as a mechanism of dominant-negative current suppression in human long QT syndrome

21 January 2018

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The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations

21 January 2018

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Role of glycosylation in cell surface expression and stability of HERG potassium channels

21 January 2018

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Mutant vasopressin precursors that cause autosomal dominant neurohypophyseal diabetes insipidus retain dimerization and impair the secretion of wild-type proteins.

21 January 2018

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21 January 2018

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An impaired routing of wild-type aquaporin-2 after tetramerization with an aquaporin-2 mutant explains dominant nephrogenic diabetes insipidus

21 January 2018

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Molecular and cellular mechanisms of cardiac arrhythmias

21 January 2018

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Identification of a trafficking determinant localized to the Kv1 potassium channel pore

21 January 2018

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Heteroligomerization of an Aquaporin-2 mutant with wild-type Aquaporin-2 and their misrouting to late endosomes/lysosomes explains dominant nephrogenic diabetes insipidus

21 January 2018

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Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death

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Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants

21 January 2018

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Novel mechanism of HERG current suppression in LQT2: shift in voltage dependence of HERG inactivation.

21 January 2018

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Characterization of S818L mutation in HERG C-terminus in LQT2. Modification of activation-deactivation gating properties.

21 January 2018

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A novel mutation (T65P) in the PAS domain of the human potassium channel HERG results in the long QT syndrome by trafficking deficiency

21 January 2018

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Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block

21 January 2018

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Spectrum of HERG K+-channel dysfunction in an inherited cardiac arrhythmia

21 January 2018

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A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

21 January 2018

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Glycerol reverses the misfolding phenotype of the most common cystic fibrosis mutation.

21 January 2018

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21 January 2018

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HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

21 January 2018

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HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects

21 January 2018

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Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects

21 January 2018

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Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature

21 January 2018

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Correction of Defective Protein Kinesis of Human P-glycoprotein Mutants by Substrates and Modulators

21 January 2018

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10.1152/AJPHEART.00052.2004

21 January 2018

Identifiers

DOI

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21 September 2017

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