(Q40013839)

16 September 2017

A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin (English)

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16 September 2017

2

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16 September 2017

13

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16 September 2017

Jennifer Conroy

3

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Navin Kumar Verma

Navin K Verma

1

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Stefania Butini

Stefania Butini

8

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Daniela M Zisterer

Daniela M Zisterer

11

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Dermot P. Kelleher

7

Dermot Kelleher

1 reference

16 September 2017

Peter Olwell

4

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16 September 2017

Anthony M Mcelligott

5

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16 September 2017

Anthony M Davies

6

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16 September 2017

Giuseppe Campiani

9

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16 September 2017

D Clive Williams

10

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16 September 2017

Mark Lawler

12

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16 September 2017

13 February 2008

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Journal of Molecular Medicine

16 September 2017

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16 September 2017

86

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16 September 2017

4

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16 September 2017

457-469

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https://scigraph.springernature.com/pub.10.1007/s00109-008-0312-8

16 September 2017

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cites work

The scaffolding protein CG-NAP/AKAP450 is a critical integrating component of the LFA-1-induced signaling complex in migratory T cells

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00109-008-0312-8

Detyrosination of tubulin regulates the interaction of intermediate filaments with microtubules in vivo via a kinesin-dependent mechanism

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00109-008-0312-8

Post-translational modifications of tubulin and microtubule stability in adult rat ventricular myocytes and immortalized HL-1 cardiomyocytes.

21 January 2018

1 reference

12 December 2020

Distribution of tyrosinated and nontyrosinated alpha-tubulin during mitosis

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12 December 2020

Suppression of endotoxin-induced inflammation by taxol.

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12 December 2020

Pyrrolo-1,5-benzoxazepines induce apoptosis in HL-60, Jurkat, and Hut-78 cells: a new class of apoptotic agents.

1 reference

12 December 2020

Activation of the c-Jun N-terminal kinase (JNK) signaling pathway is essential during PBOX-6-induced apoptosis in chronic myelogenous leukemia (CML) cells

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12 December 2020

Resistance to antimitotic drugs in Chinese hamster ovary cells correlates with changes in the level of polymerized tubulin

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12 December 2020

T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

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12 December 2020

Two-photon imaging of lymphocyte motility and antigen response in intact lymph node

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12 December 2020

Inside the crawling T cell: leukocyte function-associated antigen-1 cross-linking is associated with microtubule-directed translocation of protein kinase C isoenzymes beta(I) and delta.

1 reference

12 December 2020

A paclitaxel-eluting stent for the prevention of coronary restenosis

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12 December 2020

T cell adhesion to intercellular adhesion molecule-1 (ICAM-1) is controlled by cell spreading and the activation of integrin LFA-1

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12 December 2020

Mechanisms of action of and resistance to antitubulin agents: microtubule dynamics, drug transport, and cell death

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12 December 2020

CD44 cross-linking induces protein kinase C-regulated migration of human T lymphocytes.

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12 December 2020

Distinct populations of microtubules: tyrosinated and nontyrosinated alpha tubulin are distributed differently in vivo.

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12 December 2020

Multiple forms of tubulin: different gene products and covalent modifications

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12 December 2020

Selective induction of apoptosis by the pyrrolo-1,5-benzoxazepine 7-[[dimethylcarbamoyl]oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia cells occurs via the c-Jun NH2-terminal kinase-dependent phosphorylation and inactiva

1 reference

12 December 2020

Microtubules and signal transduction

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12 December 2020

Crucial importance of PKC-beta(I) in LFA-1-mediated locomotion of activated T cells.

1 reference

12 December 2020

A function for tubulin tyrosination?

1 reference

12 December 2020

Synthesis, biological activity, and SARs of pyrrolobenzoxazepine derivatives, a new class of specific "peripheral-type" benzodiazepine receptor ligands.

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12 December 2020

Autonomous T cell trafficking examined in vivo with intravital two-photon microscopy

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12 December 2020

PPAR-gamma expression modulates insulin sensitivity in C2C12 skeletal muscle cells

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12 December 2020

Ultrastructural colocalization of tyrosinated and detyrosinated alpha-tubulin in interphase and mitotic cells

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12 December 2020

T-cell integrins: more than just sticking points

1 reference

12 December 2020

Caspase-3 is not essential for DNA fragmentation in MCF-7 cells during apoptosis induced by the pyrrolo-1,5-benzoxazepine, PBOX-6

1 reference

12 December 2020

The specific interaction of helper T cells and antigen-presenting B cells. IV. Membrane and cytoskeletal reorganizations in the bound T cell as a function of antigen dose

1 reference

12 December 2020

Regulation of microtubules in cell migration

1 reference

12 December 2020

STI-571 (imatinib mesylate) enhances the apoptotic efficacy of pyrrolo-1,5-benzoxazepine-6, a novel microtubule-targeting agent, in both STI-571-sensitive and -resistant Bcr-Abl-positive human chronic myeloid leukemia cells.

1 reference

12 December 2020

Post-translational modifications regulate microtubule function

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12 December 2020

Identification of tubulin as the molecular target of proapoptotic pyrrolo-1,5-benzoxazepines

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12 December 2020

Microtubules are acetylated in domains that turn over slowly

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12 December 2020

Lymphocyte Foot Appendage: Its Role in Lymphocyte Function and in Immunological Reactions

1 reference

12 December 2020

The pyrrolo-1,5-benzoxazepine, PBOX-6, inhibits the growth of breast cancer cells in vitro independent of estrogen receptor status and inhibits breast tumour growth in vivo.

1 reference

12 December 2020

10.1007/S00109-008-0312-8

Identifiers

DOI

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16 September 2017

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