(Q40017153)

16 September 2017

Prolonged exposure to IL-1beta and IFNgamma induces necrosis of L929 tumor cells via a p38MAPK/NF-kappaB/NO-dependent mechanism (English)

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16 September 2017

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2

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16 September 2017

7

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16 September 2017

E Vercammen

1

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16 September 2017

A Van Den Broeke

3

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16 September 2017

M Haegman

4

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16 September 2017

L Vereecke

5

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16 September 2017

P Schotte

6

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16 September 2017

language of work or name

English

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publication date

4 February 2008

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16 September 2017

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16 September 2017

27

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16 September 2017

27

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16 September 2017

3780-3788

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https://scigraph.springernature.com/pub.10.1038/onc.2008.4

16 September 2017

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cites work

Signaling to gene activation and cell death by tumor necrosis factor receptors and Fas.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Specificity and mechanism of action of some commonly used protein kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Inhibition of human caspases by peptide-based and macromolecular inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Cell death by necrosis: towards a molecular definition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

p38 Mitogen-activated protein kinase mediates synergistic induction of inducible nitric-oxide synthase by lipopolysaccharide and interferon-gamma through signal transducer and activator of transcription 1 Ser727 phosphorylation in murine aortic endo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Phase II trial of interleukin 1 alpha and indomethacin in treatment of metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

NF-kappaB and IKK as therapeutic targets in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

IL-1beta, an immediate early protein secreted by activated microglia, induces iNOS/NO in C6 astrocytoma cells through p38 MAPK and NF-kappaB pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Regulation of the expression of inducible nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Regulation of the expression of inducible nitric oxide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

The role of TRAF6 in signal transduction and the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Interleukin-1beta-induced rat pancreatic islet nitric oxide synthesis requires both the p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Targeting signal transduction as a strategy to treat inflammatory diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Good cop, bad cop: the different faces of NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Chemotherapeutic approaches for targeting cell death pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Signal transduction of inflammatory cytokines and tumor development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Nitric oxide and its role in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Recombinant tumor necrosis factor: its effect and its synergism with interferon-gamma on a variety of normal and transformed human cell lines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

The toxic and hematologic effects of interleukin-1 alpha administered in a phase I trial to patients with advanced malignancies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

Pancreatic beta-cell-selective production of tumor necrosis factor-alpha induced by interleukin-1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.4

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.4

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Dimensions Publication ID

16 September 2017

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1 reference