(Q40026344)

English

Adenoviral vector transduction of the human deoxycytidine kinase gene enhances the cytotoxic and radiosensitizing effect of gemcitabine on experimental gliomas

scientific article published on 11 January 2008

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Adenoviral vector transduction of the human deoxycytidine kinase gene enhances the cytotoxic and radiosensitizing effect of gemcitabine on experimental gliomas (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

1 reference

based on heuristic

inferred from title

Tünde Szatmári

1

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

author name string

G Huszty

2

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

S Désaknai

3

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Europe PubMed Central

PubMed publication ID

16 September 2017

T Spasokoukotskaja

4

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

M Sasvári-Székely

5

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

M Staub

6

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

O Esik

7

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

G Sáfrány

8

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

K Lumniczky

9

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

publication date

11 January 2008

1 reference

Europe PubMed Central

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16 September 2017

Cancer Gene Therapy

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Europe PubMed Central

PubMed publication ID

16 September 2017

15

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Europe PubMed Central

PubMed publication ID

16 September 2017

3

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16 September 2017

154-164

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Europe PubMed Central

PubMed publication ID

16 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.cgt.7701115

0 references

Tumor radiosensitizers--current status of development of various approaches: report of an International Atomic Energy Agency meeting

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

21 January 2018

Sensitivity to ionizing radiation and chemotherapeutic agents in gemcitabine-resistant human tumor cell lines.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

21 January 2018

Protocol of radiotherapy for glioblastoma according to the expression of HIF-1.

1 reference

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7 January 2021

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Cancer gene therapy: combination with radiation therapy and the role of bystander cell killing in the anti-tumor effect

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

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NCIC-CTG phase II study of gemcitabine in patients with malignant glioma (IND.94).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

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Preirradiation gemcitabine chemotherapy for newly diagnosed glioblastoma. A phase II study

1 reference

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7 January 2021

based on heuristic

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Gemcitabine and radiotherapy in the treatment of brain metastases from transitional cell carcinoma of the bladder: a case report

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

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Gemcitabine twice weekly as a radiosensitiser for the treatment of brain metastases in patients with carcinoma: a phase I study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Detailed characterization of the mouse glioma 261 tumor model for experimental glioblastoma therapy

1 reference

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7 January 2021

based on heuristic

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Local tumor irradiation augments the antitumor effect of cytokine-producing autologous cancer cell vaccines in a murine glioma model

1 reference

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7 January 2021

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Local tumour irradiation enhances the anti-tumour effect of a double-suicide gene therapy system in a murine glioma model

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The intracellular localization of deoxycytidine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective assays for thymidine kinase 1 and 2 and deoxycytidine kinase and their activities in extracts from human cells and tissues.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Lactic dehydrogenase activity in blood

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunocytochemical detection of deoxycytidine kinase in pediatric malignancies in relation to in vitro cytarabine sensitivity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Decreased resistance to gemcitabine (2',2'-difluorodeoxycitidine) of cytosine arabinoside-resistant myeloblastic murine and rat leukemia cell lines: role of altered activity and substrate specificity of deoxycytidine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Drug resistance to 5-aza-2'-deoxycytidine, 2',2'-difluorodeoxycytidine, and cytosine arabinoside conferred by retroviral-mediated transfer of human cytidine deaminase cDNA into murine cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Human thymidine kinase 2: molecular cloning and characterisation of the enzyme activity with antiviral and cytostatic nucleoside substrates

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Bystander effects of nucleoside analogs phosphorylated in the cytosol or mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

2',2'-Difluoro-deoxycytidine (gemcitabine) incorporation into RNA and DNA of tumour cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Deoxynucleoside phosphorylating enzymes in monkey and human tissues show great similarities, while mouse deoxycytidine kinase has a different substrate specificity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Interspecies differences in the kinetic properties of deoxycytidine kinase elucidate the poor utility of a phase I pharmacologically directed dose-escalation concept for 2-chloro-2'-deoxyadenosine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Viral vector transduction of the human deoxycytidine kinase cDNA sensitizes glioma cells to the cytotoxic effects of cytosine arabinoside in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytotoxic activity of 2',2'-difluorodeoxycytidine, 5-aza-2'-deoxycytidine and cytosine arabinoside in cells transduced with deoxycytidine kinase gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Transduction of the human deoxycytidine kinase gene in rodent tumor cells induces in vivo growth retardation in syngeneic hosts.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Radiosensitization of pancreatic cancer cells by 2',2'-difluoro-2'-deoxycytidine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of 2'-2' difluorodeoxycytidine (gemcitabine)-induced cell cycle dysregulation in radio-enhancement of human head and neck squamous cell carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of deoxycytidine kinase (dCK) activity in gemcitabine's radioenhancement in mice and human cell lines in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

The relation between deoxycytidine kinase activity and the radiosensitising effect of gemcitabine in eight different human tumour cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of deoxycytidine kinase by gamma-irradiation and inactivation by hyperosmotic shock in human lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene therapy based on gemcitabine chemosensitization suppresses pancreatic tumor growth.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of human dCK suggests strategies to improve anticancer and antiviral therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701115

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.CGT.7701115

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

ResearchGate publication ID

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