(Q40030761)

English

Mitochondrial targeting of adenomatous polyposis coli protein is stimulated by truncating cancer mutations: regulation of Bcl-2 and implications for cell survival

scientific article published on 26 December 2007

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scholarly article

1 reference

Europe PubMed Central

16 September 2017

Mitochondrial targeting of adenomatous polyposis coli protein is stimulated by truncating cancer mutations: regulation of Bcl-2 and implications for cell survival (English)

1 reference

Europe PubMed Central

16 September 2017

1 reference

based on heuristic

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author name string

Mariana Brocardo

1

1 reference

Europe PubMed Central

16 September 2017

Ying Lei

2

1 reference

Europe PubMed Central

16 September 2017

Anthony Tighe

3

1 reference

Europe PubMed Central

16 September 2017

Stephen S Taylor

4

1 reference

Europe PubMed Central

16 September 2017

Myth T S Mok

5

1 reference

Europe PubMed Central

16 September 2017

Beric R Henderson

6

1 reference

Europe PubMed Central

16 September 2017

language of work or name

0 references

publication date

26 December 2007

1 reference

Europe PubMed Central

16 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

16 September 2017

283

1 reference

Europe PubMed Central

16 September 2017

9

1 reference

Europe PubMed Central

16 September 2017

5950-5959

1 reference

Europe PubMed Central

16 September 2017

APC, signal transduction and genetic instability in colorectal cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Adenomatous polyposis coli (APC) plays multiple roles in the intestinal and colorectal epithelia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Non-traditional roles for the Adenomatous Polyposis Coli (APC) tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

The ins and outs of APC and beta-catenin nuclear transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Membrane localization of adenomatous polyposis coli protein at cellular protrusions: targeting sequences and regulation by beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

The adenomatous polyposis coli protein is required for the formation of robust spindles formed in CSF Xenopus extracts.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Adenomatous polyposis coli and EB1 localize in close proximity of the mother centriole and EB1 is a functional component of centrosomes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Examination of actin and microtubule dependent APC localisations in living mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

ARM domain-dependent nuclear import of adenomatous polyposis coli protein is stimulated by the B56 alpha subunit of protein phosphatase 2A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Redefining the subcellular location and transport of APC: new insights using a panel of antibodies.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Mutated APC and Asef are involved in the migration of colorectal tumour cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Apoptosis and APC in colorectal tumorigenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

The APC tumour suppressor has a nuclear export function.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Movement of Bax from the cytosol to mitochondria during apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

A mitochondrial-targeting signal is present in the non-catalytic domain of the MELK protein kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Caspase cleavage of the APC tumor suppressor and release of an amino-terminal domain is required for the transcription-independent function of APC in apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Sulindac sulfide-induced apoptosis is enhanced by a small-molecule Bcl-2 inhibitor and by TRAIL in human colon cancer cells overexpressing Bcl-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Colonic crypt changes during adenoma development in familial adenomatous polyposis: immunohistochemical evidence for expansion of the crypt base cell population

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Cytoskeleton out of the cupboard: colon cancer and cytoskeletal changes induced by loss of APC.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

The subcellular destinations of APC proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Identification of a link between the tumour suppressor APC and the kinesin superfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Tumor-associated NH2-terminal fragments are the most stable part of the adenomatous polyposis coli protein and can be regulated by interactions with COOH-terminal domains.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Germline APC mutation on the beta-catenin binding site is associated with a decreased apoptotic level in colorectal adenomas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

The adenomatous polyposis coli protein and retinoblastoma protein are cleaved early in apoptosis and are potential substrates for caspases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Truncated APC regulates the transcriptional activity of beta-catenin in a cell cycle dependent manner

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

The APC Tumor Suppressor Promotes Transcription-Independent Apoptosis In vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708775200

21 January 2018

Identifiers

10.1074/JBC.M708775200

1 reference

Europe PubMed Central

16 September 2017

1 reference

Europe PubMed Central

16 September 2017

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