(Q40047429)

16 September 2017

title

Structure-function relationship of novel X4 HIV-1 entry inhibitors - L- and D-arginine peptide-aminoglycoside conjugates (English)

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16 September 2017

Ravi Hegde

1

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16 September 2017

Gadi Borkow

series ordinal

2

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16 September 2017

Alexander Berchanski

series ordinal

3

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16 September 2017

Aviva Lapidot

series ordinal

4

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16 September 2017

language of work or name

English

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publication date

20 November 2007

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16 September 2017

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16 September 2017

volume

274

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16 September 2017

issue

24

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16 September 2017

page(s)

6523-6536

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Multi-targeting the entrance door to block HIV-1.

16 September 2017

cites work

1 reference

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Prospects of HIV-1 entry inhibitors as novel therapeutics

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HIV coreceptors: role of structure, posttranslational modifications, and internalization in viral-cell fusion and as targets for entry inhibitors

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Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

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The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

21 January 2018

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A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor

21 January 2018

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Safe use of the CXCR4 inhibitor ALX40-4C in humans

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Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery

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Inhibition of furin by polyarginine-containing peptides: nanomolar inhibition by nona-D-arginine

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Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity

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Stability of cell-penetrating peptide-morpholino oligomer conjugates in human serum and in cells.

21 January 2018

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Structure-activity relationships of aminoglycoside-arginine conjugates that bind HIV-1 RNAs as determined by fluorescence and NMR spectroscopy

21 January 2018

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Neomycin B-arginine conjugate, a novel HIV-1 Tat antagonist: synthesis and anti-HIV activities

21 January 2018

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Structure-activity relationship of neomycin, paromomycin, and neamine-arginine conjugates, targeting HIV-1 gp120-CXCR4 binding step.

21 January 2018

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Anti-human immunodeficiency virus activity of novel aminoglycoside-arginine conjugates at early stages of infection

21 January 2018

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HIV coreceptor downregulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication

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Identification of residues of CXCR4 critical for human immunodeficiency virus coreceptor and chemokine receptor activities

21 January 2018

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Interactions among HIV gp120, CD4, and CXCR4: dependence on CD4 expression level, gp120 viral origin, conservation of the gp120 COOH- and NH2-termini and V1/V2 and V3 loops, and sensitivity to neutralizing antibodies.

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Exploring the stereochemistry of CXCR4-peptide recognition and inhibiting HIV-1 entry with D-peptides derived from chemokines

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Different stereochemical requirements for CXCR4 binding and signaling functions as revealed by an anti-HIV, D-amino acid-containing SMM-chemokine ligand

21 January 2018

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Mutations in gp41 and gp120 of HIV-1 isolates resistant to hexa-arginine neomycin B conjugate.

21 January 2018

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Human melanoma metastases express functional CXCR4.

21 January 2018

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The chemokine receptor CXCR4 as a therapeutic target for several diseases.

21 January 2018

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Development of low molecular weight CXCR4 antagonists by exploratory structural tuning of cyclic tetra- and pentapeptide-scaffolds towards the treatment of HIV infection, cancer metastasis and rheumatoid arthritis

21 January 2018

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The use of AMD3100 plus G-CSF for autologous hematopoietic progenitor cell mobilization is superior to G-CSF alone

21 January 2018

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Rapid mobilization of CD34+ cells following administration of the CXCR4 antagonist AMD3100 to patients with multiple myeloma and non-Hodgkin's lymphoma

21 January 2018

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CXCR4 regulates growth of both primary and metastatic breast cancer

21 January 2018

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Adenovirus expressing a bioluminescence reporter gene and cMAGI cell assay for the detection of HIV-1.

21 January 2018

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Blocking of cell-free and cell-associated HIV-1 transmission through human cervix organ culture with UC781.

21 January 2018

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Aminoglycoside-Derived Cationic Lipids for Gene Transfection: Synthesis of Kanamycin A Derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.06169.X

10.1111/J.1742-4658.2007.06169.X

21 January 2018

Identifiers

DOI

1 reference

16 September 2017

1 reference