(Q40048581)

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The Diacylglycerol-dependent translocation of ras guanine nucleotide-releasing protein 4 inside a human mast cell line results in substantial phenotypic changes, including expression of interleukin 13 receptor alpha2.

scientific article published on 16 November 2007

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27 December 2019

The Diacylglycerol-dependent translocation of ras guanine nucleotide-releasing protein 4 inside a human mast cell line results in substantial phenotypic changes, including expression of interleukin 13 receptor alpha2 (English)

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Europe PubMed Central

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27 December 2019

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based on heuristic

inferred from title

phenotypic change

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based on heuristic

inferred from title

William E Hughes

5

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Europe PubMed Central

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27 December 2019

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27 December 2019

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Gregory P Katsoulotos

1

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27 December 2019

Miao Qi

2

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27 December 2019

Jian Cheng Qi

3

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27 December 2019

Kumiko Tanaka

4

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27 December 2019

Timothy J Molloy

6

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27 December 2019

Richard L Stevens

8

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27 December 2019

Steven A Krilis

9

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27 December 2019

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16 November 2007

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27 December 2019

Journal of Biological Chemistry

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27 December 2019

283

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27 December 2019

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27 December 2019

1610-1621

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27 December 2019

Regulation of Ras in lymphocytes: get a GRP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

RasGRP is essential for mouse thymocyte differentiation and TCR signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

CalDAG-GEFIII activation of Ras, R-ras, and Rap1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-gamma2 to Ras in B cell receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

RasGRP1 and RasGRP3 regulate B cell proliferation by facilitating B cell receptor-Ras signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

The germinal center kinase gene and a novel CDC25-like gene are located in the vicinity of the PYGM gene on 11q13

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Characterization of RasGRP2, a plasma membrane-targeted, dual specificity Ras/Rap exchange factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosa

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Phenotypic changes of bone marrow-derived mast cells after intraperitoneal transfer into W/Wv mice that are genetically deficient in mast cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Cloning of rat Ras guanine nucleotide releasing protein 4, and evaluation of its expression in rat mast cells and their bone marrow progenitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Mast cells in airway hyporesponsive C3H/HeJ mice express a unique isoform of the signaling protein Ras guanine nucleotide releasing protein 4 that is unresponsive to diacylglycerol and phorbol esters.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Establishment of an immature mast cell line from a patient with mast cell leukemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Arachidonic acid metabolism in the human mast cell line HMC-1: 5-lipoxygenase gene expression and biosynthesis of thromboxane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

RasGRP4 regulates the expression of prostaglandin D2 in human and rat mast cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Improved green fluorescent protein by molecular evolution using DNA shuffling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Exchange factors of the RasGRP family mediate Ras activation in the Golgi

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Phosphorylation of RasGRP3 on threonine 133 provides a mechanistic link between PKC and Ras signaling systems in B cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

c-kit ligand mediates increased expression of cytosolic phospholipase A2, prostaglandin endoperoxide synthase-1, and hematopoietic prostaglandin D2 synthase and increased IgE-dependent prostaglandin D2 generation in immature mouse mast cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Ras activation in Jurkat T cells following low-grade stimulation of the T-cell receptor is specific to N-Ras and occurs only on the Golgi apparatus.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Tumor promoter binding of the protein kinase C C1 homology domain peptides of RasGRPs, chimaerins, and Unc13s

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

The exchange factor and diacylglycerol receptor RasGRP3 interacts with dynein light chain 1 through its C-terminal domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Activated mast cells produce interleukin 13.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Mast Cell Recovery following Chronic Treatment with Compound 48/80

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Dexamethasone suppresses gene expression and production of IL-13 by human mast cell line and lung mast cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

IL-9 and IL-13 production by activated mast cells is strongly enhanced in the presence of lipopolysaccharide: NF-kappa B is decisively involved in the expression of IL-9.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

IL-13 receptors and signaling pathways: An evolving web

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Level of expression of IL-13R alpha 2 impacts receptor distribution and IL-13 signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

IL-13 receptor alpha 2: a regulator of IL-13 and IL-4 signal transduction in primary human fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Mast cells express IL-13R alpha 1: IL-13 promotes human lung mast cell proliferation and Fc epsilon RI expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Molecular cloning of canine IL-13 receptor alpha chain (alpha1 and alpha2) cDNAs and detection of corresponding mRNAs in canine tissues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

T helper cell type 2 cytokines coordinately regulate immunoglobulin E-dependent cysteinyl leukotriene production by human cord blood-derived mast cells: profound induction of leukotriene C(4) synthase expression by interleukin 4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707042200

21 January 2018

Identifiers

10.1074/JBC.M707042200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18024961%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18024961%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

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