(Q40049783)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18021296%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

title

Assessment of the direct and indirect effects of MPP+ and dopamine on the human proteasome: implications for Parkinson's disease aetiology (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18021296%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference

5

1 reference

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26 December 2019

author name string

Begoña Caneda-Ferrón

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18021296%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Luigi A De Girolamo

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18021296%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Teresa Costa

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18021296%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Katy E Beck

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18021296%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

E Ellen Billett

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18021296%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

language of work or name

English

0 references

publication date

16 November 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18021296%20AND%20SRC:MED&resulttype=core&format=json

Journal of Neurochemistry

26 December 2019

published in

1 reference

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26 December 2019

volume

105

1 reference

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26 December 2019

issue

1

1 reference

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26 December 2019

page(s)

225-238

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18021296%20AND%20SRC:MED&resulttype=core&format=json

Experimental models of Parkinson's disease

26 December 2019

cites work

1 reference

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ATP hydrolysis by the proteasome regulatory complex PAN serves multiple functions in protein degradation

21 January 2018

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Dopamine toxicity involves mitochondrial complex I inhibition: implications to dopamine-related neuropsychiatric disorders

21 January 2018

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

21 January 2018

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Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system

21 January 2018

1 reference

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Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease

21 January 2018

1 reference

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The parkinsonian neurotoxin MPP+ opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism.

21 January 2018

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Use of the MTT assay for estimating toxicity in primary astrocyte and C6 glioma cell cultures

21 January 2018

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Metabolism and functions of glutathione in brain.

21 January 2018

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Transcriptome analysis reveals link between proteasomal and mitochondrial pathways in Parkinson's disease.

21 January 2018

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Oxidative stress, induced by 6-hydroxydopamine, reduces proteasome activities in PC12 cells: implications for the pathogenesis of Parkinson's disease

21 January 2018

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Genetics of Parkinson disease: paradigm shifts and future prospects.

21 January 2018

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Regulatory subunit interactions of the 26S proteasome, a complex problem

21 January 2018

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Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein

21 January 2018

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The decrease of NAD(P)H has a prominent role in dopamine toxicity

21 January 2018

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Inhibition of brain mitochondrial respiration by dopamine: involvement of H(2)O(2) and hydroxyl radicals but not glutathione-protein-mixed disulfides

21 January 2018

1 reference

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Functions of the proteasome: the lysis at the end of the tunnel

21 January 2018

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Mitochondrial function, GSH and iron in neurodegeneration and Lewy body diseases.

21 January 2018

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Oxidative modification of proteasome: identification of an oxidation-sensitive subunit in 26 S proteasome

21 January 2018

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Glutathione decreases in dopaminergic PC12 cells interfere with the ubiquitin protein degradation pathway: relevance for Parkinson's disease?

21 January 2018

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Parkin increases dopamine uptake by enhancing the cell surface expression of dopamine transporter

21 January 2018

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Parkin suppresses the expression of monoamine oxidases

21 January 2018

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Secondary inhibition of 2-ketoglutarate dehydrogenase complex by MPTP.

21 January 2018

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Nuclear magnetic relaxation dispersion profiles of substantia nigra pars compacta in Parkinson's disease patients are consistent with protein aggregation.

21 January 2018

1 reference

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Proteasomal function is impaired in substantia nigra in Parkinson's disease

21 January 2018

1 reference

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Protein aggregation in the pathogenesis of familial and sporadic Parkinson's disease

21 January 2018

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Failure of the ubiquitin-proteasome system in Parkinson's disease

21 January 2018

1 reference

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Altered proteasomal function in sporadic Parkinson's disease

21 January 2018

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Mitochondrial involvement in Parkinson's disease

21 January 2018

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The rotenone model of Parkinson's disease.

21 January 2018

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

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The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety

21 January 2018

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Comparative resistance of the 20S and 26S proteasome to oxidative stress.

21 January 2018

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Complex I inhibitor effect on the nigral and striatal release of dopamine in the presence and absence of nomifensine.

21 January 2018

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Mitochondrial complex I deficiency in Parkinson's disease

21 January 2018

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An inhibitor of mitochondrial complex I, rotenone, inactivates proteasome by oxidative modification and induces aggregation of oxidized proteins in SH-SY5Y cells

21 January 2018

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Dopamine toxicity in neuroblastoma cells: role of glutathione depletion by L-BSO and apoptosis

21 January 2018

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alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome

21 January 2018

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Ubiquitination of alpha-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function

21 January 2018

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Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease

21 January 2018

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Vitamin C inactivates the proteasome inhibitor PS-341 in human cancer cells

21 January 2018

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