(Q40065439)

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B cell activation state-governed formation of germinal centers following viral infection.

scientific article published on November 2007

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17947661

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B cell activation state-governed formation of germinal centers following viral infection (English)

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Katja Fink

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Anita Schildknecht

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Jacqueline Weber

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Beatrice M Senn

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Hans Hengartner

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1 November 2007

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Journal of Immunology

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179

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9

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5877-5885

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Humoral immune responses in CD40 ligand-deficient mice

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B cell receptor signal strength determines B cell fate

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Antiviral protection and germinal center formation, but impaired B cell memory in the absence of CD19.

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Induction of long-lived germinal centers associated with persisting antigen after viral infection

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Imprinting the fate of antigen-reactive B cells through the affinity of the B cell receptor.

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The role of somatic mutation in the generation of the protective humoral immune response against vesicular stomatitis virus.

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Viral superantigen drives extrafollicular and follicular B cell differentiation leading to virus-specific antibody production

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Short-lived plasmablasts dominate the early spontaneous rheumatoid factor response: differentiation pathways, hypermutating cell types, and affinity maturation outside the germinal center

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B cell tolerance checkpoints that restrict pathways of antigen-driven differentiation

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CXCR5-dependent seeding of follicular niches by B and Th cells augments antiviral B cell responses

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Kinetics of the Apoptotic Response Induced by Anti-IgM Engagement of the B Cell Receptor Is Dependent on the Density of Cell Surface Immunoglobulin M Expression

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Plasmodium chabaudi chabaudi infection in mice induces strong B cell responses and striking but temporary changes in splenic cell distribution

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Distinctive characteristics of germinal center B cells

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ICOS is essential for effective T-helper-cell responses

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Parameters governing exhaustion of rare T cell-independent neutralizing IgM-producing B cells after LCMV infection

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Characterization of (4-hydroxy-3-nitrophenyl)acetyl (NP)-specific germinal center B cells and antigen-binding B220- cells after primary NP challenge in mice.

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Cyclic re-entry of germinal center B cells and the efficiency of affinity maturation

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The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation

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Dendritic cell-independent B cell activation during acute virus infection: a role for early CCR7-driven B-T helper cell collaboration

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Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation

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Reaction of germinal centers in the T-cell-independent response to the bacterial polysaccharide alpha(1-->6)dextran

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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations

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Antiviral immune responses in gene-targeted mice expressing the immunoglobulin heavy chain of virus-neutralizing antibodies

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(Q40065439)

B cell activation state-governed formation of germinal centers following viral infection.

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