(Q40073976)

17 September 2017

title

2'-C-Methyl branched pyrimidine ribonucleoside analogues: potent inhibitors of RNA virus replication (English)

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17 September 2017

Samira Benzaria

1

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17 September 2017

Dorothée Bardiot

2

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17 September 2017

Tony Bouisset

3

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17 September 2017

Clément Counor

4

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17 September 2017

Céline Rabeson

5

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17 September 2017

Claire Pierra

6

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17 September 2017

Richard Storer

7

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17 September 2017

Anna Giulia Loi

8

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17 September 2017

Alessandra Cadeddu

9

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17 September 2017

Massimo Mura

10

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17 September 2017

Chiara Musiu

11

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17 September 2017

Michel Liuzzi

12

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17 September 2017

Roberta Loddo

13

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17 September 2017

Svetlana Bergelson

14

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17 September 2017

Vadim Bichko

15

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17 September 2017

Edward Bridges

16

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17 September 2017

Erika Cretton-Scott

17

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17 September 2017

John Mao

18

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17 September 2017

Jean-Pierre Sommadossi

19

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17 September 2017

Maria Seifer

20

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17 September 2017

David Standring

21

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17 September 2017

Michele Tausek

22

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17 September 2017

Gilles Gosselin

23

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17 September 2017

Paolo La Colla

24

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17 September 2017

publication date

1 January 2007

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Antiviral Chemistry & Chemotherapy

17 September 2017

published in

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17 September 2017

volume

18

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17 September 2017

issue

4

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17 September 2017

page(s)

225-242

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Synthesis, in vitro antiviral evaluation, and stability studies of bis(S-acyl-2-thioethyl) ester derivatives of 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA) as potential PMEA prodrugs with improved oral bioavailability

17 September 2017

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Effect of beta-enantiomeric and racemic nucleoside analogues on mitochondrial functions in HepG2 cells. Implications for predicting drug hepatotoxicity

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Antivirals and antiviral strategies

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Synthesis of 9-(2-beta-C-methyl-beta-d-ribofuranosyl)-6-substituted purine derivatives as inhibitors of HCV RNA replication.

21 January 2018

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Designing a pronucleotide stratagem: lessons from amino acid phosphoramidates of anticancer and antiviral pyrimidines

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A practical synthesis of L-FMAU from L-arabinose.

21 January 2018

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Structure-activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase

21 January 2018

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Structure-activity relationship of heterobase-modified 2'-C-methyl ribonucleosides as inhibitors of hepatitis C virus RNA replication

21 January 2018

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Identification of potent, selective P2Y-purinoceptor agonists: structure-activity relationships for 2-thioether derivatives of adenosine 5'-triphosphate

21 January 2018

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Antivirals at the mirror: the lack of stereospecificity of some viral and human enzymes offers novel opportunities in antiviral drug development.

21 January 2018

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L-nucleosides: antiviral activity and molecular mechanism

21 January 2018

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Current therapy and new molecular approaches to antiviral treatment and prevention of hepatitis C.

21 January 2018

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Template nucleotide moieties required for de novo initiation of RNA synthesis by a recombinant viral RNA-dependent RNA polymerase

21 January 2018

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The novel nucleoside analog R1479 (4'-azidocytidine) is a potent inhibitor of NS5B-dependent RNA synthesis and hepatitis C virus replication in cell culture

21 January 2018

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Evolution and taxonomy of positive-strand RNA viruses: implications of comparative analysis of amino acid sequences

21 January 2018

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Mononucleoside phosphotriester derivatives with S-acyl-2-thioethyl bioreversible phosphate-protecting groups: intracellular delivery of 3'-azido-2',3'-dideoxythymidine 5'-monophosphate

21 January 2018

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21 January 2018

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The face of future hepatitis C antiviral drug development: recent biological and virologic advances and their translation to drug development and clinical practice

21 January 2018

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Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitro

21 January 2018

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Mechanism of Activation of -D-2'-Deoxy-2'-Fluoro-2'-C-Methylcytidine and Inhibition of Hepatitis C Virus NS5B RNA Polymerase

21 January 2018

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A 7-deaza-adenosine analog is a potent and selective inhibitor of hepatitis C virus replication with excellent pharmacokinetic properties

21 January 2018

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Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

21 January 2018

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SATE pronucleotide approaches: an overview

21 January 2018

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Synthesis and pharmacokinetics of valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine.

21 January 2018

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Antiviral activity and intracellular metabolism of bis(tButylSATE) phosphotriester of beta-L-2',3'dideoxyadenosine, a potent inhibitor of HIV and HBV replication

21 January 2018

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Synthesis and evaluation of S-acyl-2-thioethyl esters of modified nucleoside 5'-monophosphates as inhibitors of hepatitis C virus RNA replication.

21 January 2018

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Prodrugs of biologically active phosphate esters

21 January 2018

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Inhibitory Effect of 2'-Substituted Nucleosides on Hepatitis C Virus Replication Correlates with Metabolic Properties in Replicon Cells

21 January 2018

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Hepatitis C virus therapies: current treatments, targets and future perspectives

21 January 2018

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Enantioselectivity of the antiviral effects of nucleoside analogues

21 January 2018

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10.1177/095632020701800406

21 January 2018

Identifiers

DOI

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17 September 2017

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