(Q40083895)

English

A caspase-3-cleaved fragment of the glial glutamate transporter EAAT2 is sumoylated and targeted to promyelocytic leukemia nuclear bodies in mutant SOD1-linked amyotrophic lateral sclerosis

scientific article published on 6 September 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

A caspase-3-cleaved fragment of the glial glutamate transporter EAAT2 is sumoylated and targeted to promyelocytic leukemia nuclear bodies in mutant SOD1-linked amyotrophic lateral sclerosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

amyotrophic lateral sclerosis

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5

object named as

Robert H Brown

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Stefano Gustincich

4

object named as

Stefano Gustincich

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

author name string

Stuart L Gibb

1

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

William Boston-Howes

2

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Zeno S Lavina

3

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Piera Pasinelli

6

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Davide Trotti

7

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

language of work or name

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publication date

6 September 2007

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

17 September 2017

282

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

44

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

32480-32490

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Astrocyte and muscle-derived secreted factors differentially regulate motoneuron survival.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Glutamate uptake

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Onset and progression in inherited ALS determined by motor neurons and microglia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

ALS: a disease of motor neurons and their nonneuronal neighbors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Molecular biology of amyotrophic lateral sclerosis: insights from genetics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Increased expression of the glial glutamate transporter EAAT2 modulates excitotoxicity and delays the onset but not the outcome of ALS in mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Caspase-3 cleaves and inactivates the glutamate transporter EAAT2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

SUMO: a history of modification

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

The small ubiquitin-like modifier-1 (SUMO-1) consensus sequence mediates Ubc9 binding and is essential for SUMO-1 modification

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

In vitro modification of human centromere protein CENP-C fragments by small ubiquitin-like modifier (SUMO) protein: definitive identification of the modification sites by tandem mass spectrometry analysis of the isopeptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

SUMO: ligases, isopeptidases and nuclear pores

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Apoptin is modified by SUMO conjugation and targeted to promyelocytic leukemia protein nuclear bodies.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Sumoylation silences the plasma membrane leak K+ channel K2P1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

SUMO modification regulates inactivation of the voltage-gated potassium channel Kv1.5.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

The mechanisms of PML-nuclear body formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

SUMO on the road to neurodegeneration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Structure of a glutamate transporter homologue from Pyrococcus horikoshii

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Cross-talk between calpain and caspase proteolytic systems during neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

A Kruppel zinc finger of ZNF 146 interacts with the SUMO-1 conjugating enzyme UBC9 and is sumoylated in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

SUMO modification of Huntingtin and Huntington's disease pathology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Impaired glutamate uptake in the R6 Huntington's disease transgenic mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Intra-nuclear trafficking of the BLM helicase to DNA damage-induced foci is regulated by SUMO modification

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

SUMO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

The transcriptional role of PML and the nuclear body

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Transgenic SOD1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Evidence for astrocytosis in ALS demonstrated by [11C](L)-deprenyl-D2 PET.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Caspase 3 activation is essential for neuroprotection in preconditioning

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Proteinase-3 induces procaspase-3 activation in the absence of apoptosis: potential role of this compartmentalized activation of membrane-associated procaspase-3 in neutrophils

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Pias1 interaction and sumoylation of metabotropic glutamate receptor 8

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

The sentrin-conjugating enzyme mUbc9 interacts with GLUT4 and GLUT1 glucose transporters and regulates transporter levels in skeletal muscle cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Global shifts in protein sumoylation in response to electrophile and oxidative stress.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Global analyses of sumoylated proteins in Saccharomyces cerevisiae. Induction of protein sumoylation by cellular stresses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

SUMO-1 modification increases human SOD1 stability and aggregation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

The function of PML in p53-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

DNA viruses and viral proteins that interact with PML nuclear bodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

PML nuclear bodies: dynamic sensors of DNA damage and cellular stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

PML is essential for multiple apoptotic pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Role and fate of PML nuclear bodies in response to interferon and viral infections

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Role of PML in cell growth and the retinoic acid pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

PML bodies: a meeting place for genomic loci?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Specific interaction of PML bodies with the TP53 locus in Jurkat interphase nuclei

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

c-Jun and p53 Activity Is Modulated by SUMO-1 Modification

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704314200

21 January 2018

Identifiers

10.1074/JBC.M704314200

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

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