(Q40088472)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18499664%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Rett syndrome-causing mutations in human MeCP2 result in diverse structural changes that impact folding and DNA interactions (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18499664%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18499664%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Rachel A Horowitz-Scherer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18499664%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Tatiana Nikitina

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18499664%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Lila M Gierasch

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18499664%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Christopher L Woodcock

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18499664%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

language of work or name

English

0 references

publication date

22 May 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18499664%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

number of pages

12

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18499664%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

283

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18499664%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18499664%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

20523-20534

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18499664%20AND%20SRC:MED&resulttype=core&format=json

Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo

7 January 2020

cites work

1 reference

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MeCP2 binding to DNA depends upon hydration at methyl-CpG

22 September 2017

1 reference

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Restoration of p53 to limit tumor growth

22 September 2017

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Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes

22 September 2017

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Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation

22 September 2017

1 reference

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Structure-function-rescue: the diverse nature of common p53 cancer mutants

22 September 2017

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Functional anthology of intrinsic disorder. 1. Biological processes and functions of proteins with long disordered regions.

22 September 2017

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Intrinsic disorder and autonomous domain function in the multifunctional nuclear protein, MeCP2.

22 September 2017

1 reference

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MECP2 mutations in males.

22 September 2017

1 reference

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Reversal of neurological defects in a mouse model of Rett syndrome

22 September 2017

1 reference

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Structural basis for understanding oncogenic p53 mutations and designing rescue drugs

22 September 2017

1 reference

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Molecular genetics of Rett syndrome: when DNA methylation goes unrecognized

22 September 2017

1 reference

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Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2.

22 September 2017

1 reference

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The Amber biomolecular simulation programs

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

DICHROWEB, an online server for protein secondary structure analyses from circular dichroism spectroscopic data

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Paradoxical role of methyl-CpG-binding protein 2 in Rett syndrome.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

MeCP2 and MBD2 expression in human neoplastic and non-neoplastic breast tissue and its association with oestrogen receptor status

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

DNA Methylation-Related Chromatin Remodeling in Activity-Dependent Bdnf Gene Regulation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Chromatin compaction by human MeCP2. Assembly of novel secondary chromatin structures in the absence of DNA methylation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Rett syndrome and MeCP2: linking epigenetics and neuronal function

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Methyl CpG-binding proteins and transcriptional repression

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

DNA sequence-dependent folding determines the divergence in binding specificities between Maf and other bZIP proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Functional consequences of Rett syndrome mutations on human MeCP2.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

DNA recognition by the methyl-CpG binding domain of MeCP2.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

The penultimate rotamer library

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

The solution structure of the domain from MeCP2 that binds to methylated DNA

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Knowledge-based protein secondary structure assignment

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Comparison of and limits of accuracy for statistical analyses of vibrational and electronic circular dichroism spectra in terms of correlations to and predictions of protein secondary structure.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

A simple method for displaying the hydropathic character of a protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Spatio-temporal dynamics and localization of MeCP2 and pathological mutants in living cells.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Altered protein conformation on DNA binding by Fos and Jun.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Analysis of the circular dichroism spectrum of proteins using the convex constraint algorithm: a practical guide.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Multiple modes of interaction between the methylated DNA binding protein MeCP2 and chromatin.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Effects of common cancer mutations on stability and DNA binding of full-length p53 compared with isolated core domains.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Denaturing action of urea and guanidine hydrochloride towards two thermophilic esterases.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

DICHROWEB: an interactive website for the analysis of protein secondary structure from circular dichroism spectra.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Functional analyses of MeCP2 mutations associated with Rett syndrome using transient expression systems.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

DNA-induced alpha-helical structure in the NH2-terminal domain of histone H1.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Estimation of globular protein secondary structure from circular dichroism.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459279

Folding transition in the DMA-binding domain of GCN4 on specific binding to DNA

20 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M803021200

Estimation of protein secondary structure and error analysis from circular dichroism spectra

21 January 2018

1 reference

12 December 2020

Circular dichroic analysis of denatured proteins: inclusion of denatured proteins in the reference set

1 reference

12 December 2020

Analysis of DNA-protein interactions by intrinsic fluorescence

1 reference

12 December 2020

Carboxyl-terminal peptides from histone H1 variants: DNA binding characteristics and solution conformation

1 reference

12 December 2020

An automated approach for clustering an ensemble of NMR-derived protein structures into conformationally related subfamilies

1 reference

12 December 2020

Spectrum and distribution of MECP2 mutations in 424 Rett syndrome patients: a molecular update

1 reference

12 December 2020

The methyl-CpG-binding protein MECP2 is required for prostate cancer cell growth

1 reference

12 December 2020

MeCP2-chromatin interactions include the formation of chromatosome-like structures and are altered in mutations causing Rett syndrome

1 reference

12 December 2020

Effects of Rett syndrome mutations of the methyl-CpG binding domain of the transcriptional repressor MeCP2 on selectivity for association with methylated DNA

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M803021200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18499664%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18499664%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference