(Q40094100)

17 September 2017

title

Activation of the integrated stress response regulates lovastatin-induced apoptosis (English)

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17 September 2017

Nima Niknejad

1

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17 September 2017

Melissa Morley

series ordinal

2

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17 September 2017

Jim Dimitroulakos

series ordinal

3

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17 September 2017

language of work or name

English

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publication date

14 August 2007

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Journal of Biological Chemistry

17 September 2017

number of pages

9

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based on heuristic

inferred from page(s)

published in

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17 September 2017

volume

282

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17 September 2017

issue

41

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17 September 2017

page(s)

29748-29756

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Regulation of the mevalonate pathway

17 September 2017

cites work

1 reference

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A Phase I trial of prolonged administration of lovastatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or of the cervix

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Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

21 January 2018

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Microarray and biochemical analysis of lovastatin-induced apoptosis of squamous cell carcinomas

21 January 2018

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Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response

21 January 2018

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Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase

21 January 2018

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Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis

21 January 2018

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PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis

21 January 2018

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21 January 2018

All roads lead to ATF4

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CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

21 January 2018

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Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cells

21 January 2018

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Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

21 January 2018

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Roles of CHOP/GADD153 in endoplasmic reticulum stress

21 January 2018

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Inhibition of the ubiquitin-proteasome pathway induces differential heat-shock protein response in cardiomyocytes and renders early cardiac protection

21 January 2018

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Stress induction of GRP78/BiP and its role in cancer.

21 January 2018

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IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

21 January 2018

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Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341, and MG-132.

21 January 2018

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Structure and functions of the 20S and 26S proteasomes

21 January 2018

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ER stress and the unfolded protein response

21 January 2018

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Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression

21 January 2018

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Defective macromolecule biosynthesis and cell-cycle progression in a mammalian cell starved for mevalonate

21 January 2018

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Rab7 Prevents Growth Factor-Independent Survival by Inhibiting Cell-Autonomous Nutrient Transporter Expression

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M705859200

1 reference

17 September 2017

1 reference