(Q40100872)

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Subcellular localisation of BAG-1 and its regulation of vitamin D receptor-mediated transactivation and involucrin expression in oral keratinocytes: implications for oral carcinogenesis

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Europe PubMed Central

PubMed publication ID

17 September 2017

Subcellular localisation of BAG-1 and its regulation of vitamin D receptor-mediated transactivation and involucrin expression in oral keratinocytes: implications for oral carcinogenesis (English)

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Europe PubMed Central

PubMed publication ID

17 September 2017

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Simon J Crabb

2

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object named as

Ann C Williams

5

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object named as

Graham Packham

7

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Carsten Carlberg

object named as

Carsten Carlberg

4

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author name string

San San Lee

1

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Europe PubMed Central

PubMed publication ID

17 September 2017

Nari Janghra

3

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Europe PubMed Central

PubMed publication ID

17 September 2017

Ramsey I Cutress

6

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Europe PubMed Central

PubMed publication ID

17 September 2017

Angela Hague

8

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Europe PubMed Central

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17 September 2017

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publication date

29 June 2007

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Europe PubMed Central

PubMed publication ID

17 September 2017

Experimental Cell Research

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Europe PubMed Central

PubMed publication ID

17 September 2017

313

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Europe PubMed Central

PubMed publication ID

17 September 2017

15

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Europe PubMed Central

PubMed publication ID

17 September 2017

3222-3238

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Europe PubMed Central

PubMed publication ID

17 September 2017

Mammalian cells express two differently localized Bag-1 isoforms generated by alternative translation initiation

1 reference

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Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity

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Mammalian protein RAP46: an interaction partner and modulator of 70 kDa heat shock proteins

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BAG-1 modulates the chaperone activity of Hsp70/Hsc70.

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Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1

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The retinoblastoma protein interacts with Bag-1 in human colonic adenoma and carcinoma derived cell lines

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BAG-1 expression and function in human cancer

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BAG-1 expression correlates highly with the malignant potential in early lesions (T1 and T2) of oral squamous cell carcinoma

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Bag-1 expression as a prognostic factor in tongue squamous cell carcinomas

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Deregulated Bag-1 protein expression in human oral squamous cell carcinomas and lymph node metastases

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Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells

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A protein that interacts with members of the nuclear hormone receptor family: identification and cDNA cloning

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RAP46 is a negative regulator of glucocorticoid receptor action and hormone-induced apoptosis

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BAG-1L protein enhances androgen receptor function

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The nuclear BAG-1 isoform, BAG-1L, enhances oestrogen-dependent transcription.

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Interaction of BAG-1 with retinoic acid receptor and its inhibition of retinoic acid-induced apoptosis in cancer cells

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BAG1L enhances trans-activation function of the vitamin D receptor

1 reference

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BAG-1 p50 isoform interacts with the vitamin D receptor and its cellular overexpression inhibits the vitamin D pathway

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Regulation of Terminal Differentiation of Cultured Mouse Epidermal Cells by lα,25-Dihydroxyvitamin D3*

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Effect of 1 alpha,25-dihydroxyvitamin D3 on the morphologic and biochemical differentiation of cultured human epidermal keratinocytes grown in serum-free conditions

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Human oral buccal mucosa reconstructed on dermal substrates: a model for oral epithelial differentiation

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Two nuclear signalling pathways for vitamin D

1 reference

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Difference and similarity of DNA sequence recognized by VDR homodimer and VDR/RXR heterodimer

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Cloning of the human phospholipase C-gamma1 promoter and identification of a DR6-type vitamin D-responsive element

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Natural vitamin D3 response elements formed by inverted palindromes: polarity-directed ligand sensitivity of vitamin D3 receptor-retinoid X receptor heterodimer-mediated transactivation.

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GrpE-like regulation of the hsc70 chaperone by the anti-apoptotic protein BAG-1

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Structure of a Bag/Hsc70 complex: convergent functional evolution of Hsp70 nucleotide exchange factors

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Structural analysis of BAG1 cochaperone and its interactions with Hsc70 heat shock protein

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Hsp70-RAP46 interaction in downregulation of DNA binding by glucocorticoid receptor

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Bag1-Hsp70 mediates a physiological stress signalling pathway that regulates Raf-1/ERK and cell growth.

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The behaviour of human oral squamous cell carcinoma in cell culture

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Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics

1 reference

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BAG-1 proteins protect cardiac myocytes from simulated ischemia/reperfusion-induced apoptosis via an alternate mechanism of cell survival independent of the proteasome.

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Functional characterization of a 1,25-dihydroxyvitamin D3 receptor binding site found in the rat atrial natriuretic factor promoter

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Requirement of an AP-1 site in the calcium response region of the involucrin promoter

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High level expression of differentially localized BAG-1 isoforms in some oestrogen receptor-positive human breast cancers.

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Polypyrimidine tract binding protein and poly r(C) binding protein 1 interact with the BAG-1 IRES and stimulate its activity in vitro and in vivo

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Bag-1 internal ribosome entry segment activity is promoted by structural changes mediated by poly(rC) binding protein 1 and recruitment of polypyrimidine tract binding protein 1.

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Marek's disease virus latent protein MEQ: delineation of an epitope in the BR1 domain involved in nuclear localization

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Mechanisms of gene regulation by vitamin D(3) receptor: a network of coactivator interactions.

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Mutations in the 1,25-dihydroxyvitamin D3 receptor identifying C-terminal amino acids required for transcriptional activation that are functionally dissociated from hormone binding, heterodimeric DNA binding, and interaction with basal transcription

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Lysine 246 of the vitamin D receptor is crucial for ligand-dependent interaction with coactivators and transcriptional activity

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The vitamin D response element of the involucrin gene mediates its regulation by 1,25-dihydroxyvitamin D3.

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The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation

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Epithelial structural proteins of the skin and oral cavity: function in health and disease

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Vitamin D signaling is modulated on multiple levels in health and disease.

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Conventional and nonconventional roles of the nucleolus

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Human BAG-1/RAP46 protein is generated as four isoforms by alternative translation initiation and overexpressed in cancer cells

1 reference

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Structure-function analysis of Bag1 proteins. Effects on androgen receptor transcriptional activity

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Identifiers

10.1016/J.YEXCR.2007.06.010

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

ResearchGate publication ID

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