(Q40101297)

17 September 2017

title

Targeting topoisomerase II with the chiral DNA-intercalating ruthenium(II) polypyridyl complexes (English)

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17 September 2017

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Feng Gao

1

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17 September 2017

Hui Chao

2

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17 September 2017

Jin-Quan Wang

3

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17 September 2017

Yi-Xian Yuan

4

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17 September 2017

Bin Sun

5

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17 September 2017

Yuan-Fang Wei

6

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17 September 2017

Bin Peng

7

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17 September 2017

Liang-Nian Ji

8

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17 September 2017

publication date

21 July 2007

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Journal of Biological Inorganic Chemistry

17 September 2017

published in

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17 September 2017

volume

12

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17 September 2017

issue

7

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17 September 2017

page(s)

1015-1027

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Structure and function of type II DNA topoisomerases

17 September 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FS00775-007-0272-4

The search of DNA-intercalators as antitumoral drugs: what it worked and what did not work.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00775-007-0272-4

Tris(phenanthroline)ruthenium(II) enantiomer interactions with DNA: mode and specificity of binding

21 January 2018

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12 December 2020

Quenching of fluorescence by oxygen. Probe for structural fluctuations in macromolecules

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12 December 2020

Photoelectron transfer processes with ruthenium(II) polypyridyl complexes and Cu/Zn superoxide dismutase

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12 December 2020

Topoisomerase II.etoposide interactions direct the formation of drug-induced enzyme-DNA cleavage complexes.

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12 December 2020

Dinuclear platinum complexes with N, N'-bis(aminoalkyl)-1,4-diaminoanthraquinones as linking ligands. Part I. Synthesis, cytotoxicity, and cellular studies in A2780 human ovarian carcinoma cells.

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12 December 2020

DNA interactions with ruthenium(ll) polypyridine complexes containing asymmetric ligands

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12 December 2020

Theoretical calculations of the helix-coil transition of DNA in the presence of large, cooperatively binding ligands

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12 December 2020

Synthesis of two new heteroaromatic beta-carboline-fused pentacycles. Observation of a new intercalating agent.

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12 December 2020

A protein-mediated mechanism for the DNA sequence-specific action of topoisomerase II poisons.

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12 December 2020

DNA topoisomerases: structure, function, and mechanism

1 reference

12 December 2020

Structure and mechanism of DNA topoisomerase II

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12 December 2020

DNA interactions of a functionalized ruthenium(II) mixed-polypyridyl complex [Ru(bpy)2ppd]2+

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12 December 2020

Merbarone inhibits the catalytic activity of human topoisomerase IIalpha by blocking DNA cleavage

1 reference

12 December 2020

Syntheses of ruthenium(II) quinonediimine complexes of cyclam and characterization of their DNA-binding activities and cytotoxicity

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12 December 2020

Role of superoxide in deoxyribonucleic acid strand scission

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12 December 2020

DNA topoisomerase II from Drosophila melanogaster. Relaxation of supercoiled DNA.

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12 December 2020

Intercalators as anticancer drugs.

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12 December 2020

Binding of etoposide to topoisomerase II in the absence of DNA: decreased affinity as a mechanism of drug resistance

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12 December 2020

In vitro anticancer activities and optical imaging of novel intercalative non-cisplatin conjugates

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12 December 2020

The new anticancer drug [(2R)-aminomethylpyrrolidine](1, 1-cyclobutanedicarboxylato)platinum(II) and its toxic S enantiomer do interact differently with nucleic acids.

1 reference

12 December 2020

A Novel Solid-Phase Assembly for Identifying Potent and Selective RNA Ligands We thank Professors David Wilson and David Boykin for a generous gift of the aromatic amidine derivatives and Professor Kol for a generous gift of eilatin-containing compl

1 reference

12 December 2020

Metals and DNA: molecular left-handed complements

1 reference

12 December 2020

Synthesis, DNA binding, topoisomerase inhibition and cytotoxic properties of 2-chloroethylnitrosourea derivatives of hoechst 33258.

1 reference

12 December 2020

DNA topoisomerases as targets for the anticancer drug TAS-103: DNA interactions and topoisomerase catalytic inhibition.

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12 December 2020

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

12 December 2020

Luminescence of ruthenium(II) polypyridyls: evidence for intercalative binding to Z-DNA.

1 reference

12 December 2020

Antitumor agents. 3. Design, synthesis, and biological evaluation of new pyridoisoquinolindione and dihydrothienoquinolindione derivatives with potent cytotoxic activity

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12 December 2020

DNA Gyrase and the Supercoiling of DNA

1 reference

12 December 2020

Interaction of [Ru(dmp)2(dppz)]2+ and [Ru(dmb)2(dppz)]2+ with DNA: effects of the ancillary ligands on the DNA-binding behaviors

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12 December 2020

DNA topoisomerases as targets for the anticancer drug TAS-103: primary cellular target and DNA cleavage enhancement

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12 December 2020

Inhibition of topoisomerases by antitumor prostaglandins

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12 December 2020

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12 December 2020

Enantiomeric ruthenium(II) complexes binding to DNA: binding modes and enantioselectivity

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12 December 2020

Tumor cell death induced by topoisomerase-targeting drugs.

1 reference

12 December 2020

Synthesis, characterization, DNA-binding and photocleavage studies of [Ru(bpy)2(PPIP)]2+ and [Ru(phen)2(PPIP)]2+.

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12 December 2020

Kinetically inert transition metal complexes that reversibly bind to DNA.

1 reference

12 December 2020

Studies on interaction of anthracycline antibiotics and deoxyribonucleic acid: equilibrium binding studies on interaction of daunomycin with deoxyribonucleic acid

1 reference

12 December 2020

Position-specific trapping of topoisomerase II by benzo[a]pyrene diol epoxide adducts: implications for interactions with intercalating anticancer agents

1 reference

12 December 2020

Neither delta- nor lambda-tris(phenanthroline)ruthenium(II) binds to DNA by classical intercalation

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12 December 2020

Recognition and reaction of metallointercalators with DNA.

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12 December 2020

Unambiguous evidence for the participation of singlet oxygen ( 1 ) in photodynamic oxidation of amino acids

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12 December 2020

Inhibitory properties of antitumor prostaglandins against topoisomerases

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12 December 2020

Biophysical studies of a ruthenium(II) polypyridyl complex binding to DNA and RNA prove that nucleic acid structure has significant effects on binding behaviors

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12 December 2020

Inhibition of DNA topoisomerases I and II, and growth inhibition of human cancer cell lines by a marine microalgal polysaccharide

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12 December 2020

Complex formation between ethidium bromide and nucleic acids

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12 December 2020

Topoisomerase II binds to ellipticine in the absence or presence of DNA. Characterization of enzyme-drug interactions by fluorescence spectroscopy

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12 December 2020

Tris(tetramethylphenanthroline)ruthenium(II): a chiral probe that cleaves A-DNA conformations

1 reference

12 December 2020

Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme

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12 December 2020

10.1007/S00775-007-0272-4

Identifiers

DOI

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17 September 2017

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