(Q40126113)

English

Direct interactions of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 ORF50/Rta protein with the cellular protein octamer-1 and DNA are critical for specifying transactivation of a delayed-early promoter and stimulating viral reactivati

scientific article published on 30 May 2007

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scholarly article

1 reference

Europe PubMed Central

17 September 2017

Direct interactions of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 ORF50/Rta protein with the cellular protein octamer-1 and DNA are critical for specifying transactivation of a delayed-early promoter and stimulating viral reactivati (English)

1 reference

Europe PubMed Central

17 September 2017

Kaposi's sarcoma-associated herpesvirus

object named as

human herpesvirus 8

1 reference

based on heuristic

inferred from title

author name string

Kyla Driscoll Carroll

1

1 reference

Europe PubMed Central

17 September 2017

Farah Khadim

2

1 reference

Europe PubMed Central

17 September 2017

Sophia Spadavecchia

3

1 reference

Europe PubMed Central

17 September 2017

Diana Palmeri

4

1 reference

Europe PubMed Central

17 September 2017

David M Lukac

5

1 reference

Europe PubMed Central

17 September 2017

language of work or name

0 references

publication date

30 May 2007

1 reference

Europe PubMed Central

17 September 2017

Journal of Virology

1 reference

Europe PubMed Central

17 September 2017

81

1 reference

Europe PubMed Central

17 September 2017

16

1 reference

Europe PubMed Central

17 September 2017

8451-8467

1 reference

Europe PubMed Central

17 September 2017

Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 ORF50/Rta lytic switch protein functions as a tetramer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

22 September 2017

Essential role of RBP-Jkappa in activation of the K8 delayed-early promoter of Kaposi's sarcoma-associated herpesvirus by ORF50/RTA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

22 September 2017

Kaposi's Sarcoma-associated herpesvirus lytic switch protein stimulates DNA binding of RBP-Jk/CSL to activate the Notch pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

22 September 2017

Characterization of Kaposi's sarcoma-associated herpesvirus (KSHV) K1 promoter activation by Rta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

22 September 2017

Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen modulates K1 expression through its cis-acting elements within the terminal repeats

1 reference

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22 September 2017

Host and viral proteins in the virion of Kaposi's sarcoma-associated herpesvirus

1 reference

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22 September 2017

Dissection of the Kaposi's sarcoma-associated herpesvirus gene expression program by using the viral DNA replication inhibitor cidofovir

1 reference

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22 September 2017

Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover

1 reference

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22 September 2017

The DNA architectural protein HMGB1 facilitates RTA-mediated viral gene expression in gamma-2 herpesviruses.

1 reference

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22 September 2017

Kaposi's sarcoma-associated herpesvirus ori-Lyt-dependent DNA replication: cis-acting requirements for replication and ori-Lyt-associated RNA transcription

1 reference

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22 September 2017

RBP-J (CSL) is essential for activation of the K14/vGPCR promoter of Kaposi's sarcoma-associated herpesvirus by the lytic switch protein RTA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

22 September 2017

Early activation of the Kaposi's sarcoma-associated herpesvirus RTA, RAP, and MTA promoters by the tetradecanoyl phorbol acetate-induced AP1 pathway.

1 reference

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22 September 2017

A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors

1 reference

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22 September 2017

Herpes simplex virus infections are arrested in Oct-1-deficient cells

1 reference

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22 September 2017

Embryonic lethality, decreased erythropoiesis, and defective octamer-dependent promoter activation in Oct-1-deficient mice.

1 reference

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22 September 2017

Comparative study of regulation of RTA-responsive genes in Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8.

1 reference

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22 September 2017

Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 transcriptional activator Rta is an oligomeric DNA-binding protein that interacts with tandem arrays of phased A/T-trinucleotide motifs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

22 September 2017

Lytic but not latent infection by Kaposi's sarcoma-associated herpesvirus requires host CSL protein, the mediator of Notch signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

22 September 2017

The herpes simplex virus VP16-induced complex: the makings of a regulatory switch

1 reference

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22 September 2017

Molecular genetics of Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8) epidemiology and pathogenesis

1 reference

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22 September 2017

Skp2 regulates Myc protein stability and activity

1 reference

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22 September 2017

Role of CCAAT/enhancer-binding protein alpha (C/EBPalpha) in activation of the Kaposi's sarcoma-associated herpesvirus (KSHV) lytic-cycle replication-associated protein (RAP) promoter in cooperation with the KSHV replication and transcription activa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

22 September 2017

Transcriptional regulation of the K1 gene product of Kaposi's sarcoma-associated herpesvirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

22 September 2017

Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) replication and transcription factor activates the K9 (vIRF) gene through two distinct cis elements by a non-DNA-binding mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

22 September 2017

The lytic switch protein of KSHV activates gene expression via functional interaction with RBP-Jkappa (CSL), the target of the Notch signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

22 September 2017

Transcriptional regulation of the interleukin-6 gene of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus).

1 reference

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22 September 2017

Charting latency transcripts in Kaposi's sarcoma-associated herpesvirus by whole-genome real-time quantitative PCR

1 reference

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22 September 2017

Characterization of interactions between RTA and the promoter of polyadenylated nuclear RNA in Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8.

1 reference

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22 September 2017

Open reading frame 50 protein of Kaposi's sarcoma-associated herpesvirus directly activates the viral PAN and K12 genes by binding to related response elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

22 September 2017

Octamer-binding sequence is a key element for the autoregulation of Kaposi's sarcoma-associated herpesvirus ORF50/Lyta gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

22 September 2017

DNA binding by Kaposi's sarcoma-associated herpesvirus lytic switch protein is necessary for transcriptional activation of two viral delayed early promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

22 September 2017

Transcription program of human herpesvirus 8 (kaposi's sarcoma-associated herpesvirus).

1 reference

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22 September 2017

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia

1 reference

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22 September 2017

The virtuoso of versatility: POU proteins that flex to fit

1 reference

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22 September 2017

Kaposi's sarcoma-associated herpesvirus latent and lytic gene expression as revealed by DNA arrays

1 reference

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22 September 2017

Cytokine-mediated growth promotion of Kaposi's sarcoma and primary effusion lymphoma.

1 reference

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22 September 2017

Transcriptional regulation of the Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor gene

1 reference

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22 September 2017

Human herpesvirus 8 glycoprotein K8.1: expression, post-translational modification and localization analyzed by monoclonal antibody

1 reference

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22 September 2017

Kaposi's sarcoma-associated herpesvirus open reading frame 50/Rta protein activates the entire viral lytic cycle in the HH-B2 primary effusion lymphoma cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

22 September 2017

Kaposi's sarcoma-associated herpesvirus open reading frame 57 encodes a posttranscriptional regulator with multiple distinct activities

1 reference

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22 September 2017

Functional overlap of sequences that activate transcription and signal ubiquitin-mediated proteolysis

1 reference

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22 September 2017

Histone acetylation and reactivation of Epstein-Barr virus from latency.

1 reference

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22 September 2017

Experimental transmission of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) to SCID-hu Thy/Liv mice

1 reference

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22 September 2017

TRANSFAC: an integrated system for gene expression regulation

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22 September 2017

Transcriptional activation by the product of open reading frame 50 of Kaposi's sarcoma-associated herpesvirus is required for lytic viral reactivation in B cells

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22 September 2017

Expression of the open reading frame 74 (G-protein-coupled receptor) gene of Kaposi's sarcoma (KS)-associated herpesvirus: implications for KS pathogenesis

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22 September 2017

Oral ganciclovir for patients with cytomegalovirus retinitis treated with a ganciclovir implant. Roche Ganciclovir Study Group

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22 September 2017

Kinetics of Kaposi's sarcoma-associated herpesvirus gene expression

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22 September 2017

HCF-dependent nuclear import of VP16

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22 September 2017

A viral gene that activates lytic cycle expression of Kaposi's sarcoma-associated herpesvirus

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22 September 2017

Transcription mapping of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) genome in a body cavity-based lymphoma cell line (BC-1)

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22 September 2017

Tropism of human herpesvirus 8 for peripheral blood lymphocytes in patients with Castleman's disease

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22 September 2017

Viral mimicry: common mode of association with HCF by VP16 and the cellular protein LZIP

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22 September 2017

Monocytes in Kaposi's sarcoma lesions are productively infected by human herpesvirus 8.

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22 September 2017

Interdigitated residues within a small region of VP16 interact with Oct-1, HCF, and DNA

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22 September 2017

Kaposi's sarcoma-associated herpesvirus gene expression in endothelial (spindle) tumor cells

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22 September 2017

Selective switch between latency and lytic replication of Kaposi's sarcoma herpesvirus and Epstein-Barr virus in dually infected body cavity lymphoma cells.

1 reference

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22 September 2017

The size and conformation of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) DNA in infected cells and virions

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22 September 2017

Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen

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22 September 2017

KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma

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22 September 2017

The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus): distribution of infection in KS risk groups and evidence for sexual transmission

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22 September 2017

Restricted expression of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genes in Kaposi sarcoma

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22 September 2017

Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules

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22 September 2017

Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

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22 September 2017

Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas

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22 September 2017

Proteins and cis-acting elements associated with transactivation of the varicella-zoster virus (VZV) immediate-early gene 62 promoter by VZV open reading frame 10 protein

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22 September 2017

Disruption of the mouse RBP-J kappa gene results in early embryonic death

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22 September 2017

Crystal structure of the MATa1/MAT alpha 2 homeodomain heterodimer bound to DNA

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22 September 2017

Structural features of the herpes simplex virus alpha gene 4, 0, and 27 promoter-regulatory sequences which confer alpha regulation on chimeric thymidine kinase genes

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22 September 2017

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22 September 2017

Regulation of herpesvirus macromolecular synthesis: transcription-initiation sites and domains of alpha genes

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22 September 2017

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22 September 2017

Proteins specified by herpes simplex virus. V. Purification and structural proteins of the herpesvirion

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22 September 2017

Host cell proteins bind to the cis-acting site required for virion-mediated induction of herpes simplex virus 1 alpha genes

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22 September 2017

A modular system for the assay of transcription regulatory signals: the sequence TAATGARAT is required for herpes simplex virus immediate early gene activation.

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22 September 2017

A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins

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22 September 2017

Differentiation and DNA contact points of host proteins binding at the cis site for virion-mediated induction of alpha genes of herpes simplex virus 1.

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22 September 2017

Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation

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22 September 2017

A complex formed between cell components and an HSV structural polypeptide binds to a viral immediate early gene regulatory DNA sequence

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22 September 2017

The octamer-binding proteins form multi-protein--DNA complexes with the HSV alpha TIF regulatory protein

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22 September 2017

Overlapping octamer and TAATGARAT motifs in the VF65-response elements in herpes simplex virus immediate-early promoters represent independent binding sites for cellular nuclear factor III

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22 September 2017

Differential transcriptional activation by Oct-1 and Oct-2: interdependent activation domains induce Oct-2 phosphorylation

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22 September 2017

Ubiquitous transcription factor OTF-1 mediates induction of the MMTV promoter through synergistic interaction with hormone receptors

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22 September 2017

Activation of human herpesvirus 8 (HHV-8) thymidine kinase (TK) TATAA-less promoter by HHV-8 ORF50 gene product is SP1 dependent

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25 September 2017

Detection of Kaposi sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

25 September 2017

POU proteins bend DNA via the POU-specific domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

25 September 2017

Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

25 September 2017

Evidence of DNA: protein interactions that mediate HSV-1 immediate early gene activation by VP16.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

25 September 2017

A Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 ORF50 deletion mutant is defective for reactivation of latent virus and DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

17 June 2018

Differential regulation of K8 gene expression in immediate-early and delayed-early stages of Kaposi's sarcoma-associated herpesvirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

17 June 2018

Viral G protein-coupled receptor and Kaposi's sarcoma: a model of paracrine neoplasia?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

17 June 2018

Infectious human herpesvirus 8 in a healthy North American blood donor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

17 June 2018

Primary effusion lymphoma: a distinct clinicopathologic entity associated with the Kaposi's sarcoma-associated herpes virus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

17 June 2018

Human herpesvirus 8 is present in the lymphoid system of healthy persons and can reactivate in the course of AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

17 June 2018

The herpes simplex virus trans-activator VP16 recognizes the Oct-1 homeo domain: evidence for a homeo domain recognition subdomain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

17 June 2018

A putative stimulatory role for activator turnover in gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

20 August 2018

Herpes-like sequences in HIV-infected and uninfected Kaposi's sarcoma patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951345

20 August 2018

OBP100 binds remarkably degenerate octamer motifs through specific interactions with flanking sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/17537858

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site-specific conformational alteration of the Oct-1 POU domain-DNA complex as the basis for differential recognition by Vmw65 (VP16)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17537858

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human herpesvirus type 8 DNA sequences in cell-free plasma and mononuclear cells of Kaposi's sarcoma patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17537858

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17537858

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CCAAT/enhancer-binding protein-alpha is induced during the early stages of Kaposi's sarcoma-associated herpesvirus (KSHV) lytic cycle reactivation and together with the KSHV replication and transcription activator (RTA) cooperatively stimulates the

1 reference

https://pubmed.ncbi.nlm.nih.gov/17537858

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactivation of Kaposi's sarcoma-associated herpesvirus infection from latency by expression of the ORF 50 transactivator, a homolog of the EBV R protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17537858

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The KSHV immediate-early transcription factor RTA encodes ubiquitin E3 ligase activity that targets IRF7 for proteosome-mediated degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17537858

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.00265-07

1 reference

Europe PubMed Central

17 September 2017

1 reference

Europe PubMed Central

17 September 2017

1 reference

Europe PubMed Central

17 September 2017

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