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English
Apoptosis induced by histone deacetylase inhibitors in leukemic cells is mediated by Bim and Noxa.
scientific article published on 24 May 2007
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
17525724
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17525724%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
title
Apoptosis induced by histone deacetylase inhibitors in leukemic cells is mediated by Bim and Noxa
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
17525724
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17525724%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
main subject
leukemia
1 reference
based on heuristic
inferred from title
apoptotic process
1 reference
based on heuristic
inferred from title
author
Martin Dyer
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
17525724
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17525724%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
author name string
S Inoue
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
17525724
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17525724%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
J Riley
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
17525724
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17525724%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
T W Gant
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
17525724
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17525724%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
G M Cohen
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed ID
17525724
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17525724%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
publication date
24 May 2007
1 reference
stated in
Europe PubMed Central
PubMed ID
17525724
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17525724%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
published in
Leukemia
1 reference
stated in
Europe PubMed Central
PubMed ID
17525724
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17525724%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
volume
21
1 reference
stated in
Europe PubMed Central
PubMed ID
17525724
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17525724%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
issue
8
1 reference
stated in
Europe PubMed Central
PubMed ID
17525724
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17525724%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
page(s)
1773-1782
1 reference
stated in
Europe PubMed Central
PubMed ID
17525724
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17525724%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.leu.2404760
0 references
cites work
Histone deacetylases and cancer: causes and therapies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404760
retrieved
7 January 2021
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inferred from DOI database lookup
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404760
retrieved
7 January 2021
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inferred from DOI database lookup
Histone deacetylase inhibitors: insights into mechanisms of lethality
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404760
retrieved
7 January 2021
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inferred from DOI database lookup
The role of BH3-only proteins in the immune system
1 reference
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Crossref
reference URL
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7 January 2021
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The Bcl2 family: regulators of the cellular life-or-death switch
1 reference
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Crossref
reference URL
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7 January 2021
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BH3-Only proteins-essential initiators of apoptotic cell death
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404760
retrieved
7 January 2021
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inferred from DOI database lookup
Life in the balance: how BH3-only proteins induce apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404760
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BH3-only proteins in cell death initiation, malignant disease and anticancer therapy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404760
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404760
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404760
retrieved
7 January 2021
based on heuristic
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The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species
1 reference
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Crossref
reference URL
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7 January 2021
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Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA).
1 reference
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Crossref
reference URL
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7 January 2021
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Histone deacetylase inhibitors FK228, N-(2-aminophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)amino- methyl]benzamide and m-carboxycinnamic acid bis-hydroxamide augment radiation-induced cell death in gastrointestinal adenocarcinoma cells
1 reference
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Crossref
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Histone deacetylase inhibitors potentiate TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in lymphoid malignancies.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404760
retrieved
7 January 2021
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Bmf is a possible mediator in histone deacetylase inhibitors FK228 and CBHA-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404760
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bmf contributes to histone deacetylase inhibitor-mediated enhancing effects on apoptosis after ionizing radiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404760
retrieved
7 January 2021
based on heuristic
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Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404760
retrieved
7 January 2021
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The histone deacetylase inhibitor MS-275 induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia cells
1 reference
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Crossref
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7 January 2021
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Depsipeptide (FR901228) induces histone acetylation and inhibition of histone deacetylase in chronic lymphocytic leukemia cells concurrent with activation of caspase 8-mediated apoptosis and down-regulation of c-FLIP protein
1 reference
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7 January 2021
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Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia.
1 reference
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Crossref
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7 January 2021
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Inhibition of Histone Deacetylase Class I but not Class II Is Critical for the Sensitization of Leukemic Cells to Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Induced Apoptosis
1 reference
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Upregulation of TRAIL-R2 is not involved in HDACi mediated sensitization to TRAIL-induced apoptosis
1 reference
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Chronic lymphocytic leukemic cells exhibit apoptotic signaling via TRAIL-R1.
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TRAIL receptor-selective mutants signal to apoptosis via TRAIL-R1 in primary lymphoid malignancies
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Z-138: a new mature B-cell acute lymphoblastic leukemia cell line from a patient with transformed chronic lymphocytic leukemia
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Transforming growth factor beta-dependent sequential activation of Smad, Bim, and caspase-9 mediates physiological apoptosis in gastric epithelial cells
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Valproic acid-induced gene expression through production of reactive oxygen species
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Targeting tumor angiogenesis with histone deacetylase inhibitors: the hydroxamic acid derivative LBH589.
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New stem cell center at Cornell
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7 January 2021
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Histone deacetylase inhibitors down-regulate bcl-2 expression and induce apoptosis in t(14;18) lymphomas
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7 January 2021
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Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation
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BAX frameshift mutations in cell lines derived from human haemopoietic malignancies are associated with resistance to apoptosis and microsatellite instability
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7 January 2021
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DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
1 reference
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7 January 2021
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Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity
1 reference
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Intrinsic apoptotic and thioredoxin pathways in human prostate cancer cell response to histone deacetylase inhibitor
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Modulation of pro- and anti-apoptotic factors in human melanoma cells exposed to histone deacetylase inhibitors.
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Crossref
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7 January 2021
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A gene atlas of the mouse and human protein-encoding transcriptomes
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1 reference
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7 January 2021
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2404760
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7 January 2021
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inferred from DOI database lookup
p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa
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7 January 2021
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E1A activates transcription of p73 and Noxa to induce apoptosis
1 reference
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Crossref
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Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis
1 reference
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Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: therapeutic implications.
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Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells
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The Molecular Mechanism of Noxa-induced Mitochondrial Dysfunction in p53-Mediated Cell Death
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7 January 2021
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Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.
1 reference
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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
1 reference
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Crossref
reference URL
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Identifiers
DOI
10.1038/SJ.LEU.2404760
1 reference
stated in
Europe PubMed Central
PubMed ID
17525724
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17525724%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
Dimensions Publication ID
1044046184
0 references
PubMed ID
17525724
1 reference
stated in
Europe PubMed Central
PubMed ID
17525724
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17525724%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
ResearchGate publication ID
6306666
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