(Q36463059)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16645634%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

review article

1 reference

title

BH3-only proteins in cell death initiation, malignant disease and anticancer therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16645634%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16645634%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Erlacher M

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16645634%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Kiessling S

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16645634%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Villunger A

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16645634%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

publication date

28 April 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16645634%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

20 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16645634%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16645634%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16645634%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

1325-1338

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16645634%20AND%20SRC:MED&resulttype=core&format=json

Cell death: critical control points

20 January 2020

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21 January 2018

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21 January 2018

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21 January 2018

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PUMA mediates the apoptotic response to p53 in colorectal cancer cells

21 January 2018

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Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway

21 January 2018

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21 January 2018

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PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

21 January 2018

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The role of the Bcl-2 protein family in cancer

21 January 2018

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VavP-Bcl2 transgenic mice develop follicular lymphoma preceded by germinal center hyperplasia

21 January 2018

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Selective regulation of Bcl-XL by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies

21 January 2018

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Complementary functions of the antiapoptotic protein A1 and serine/threonine kinase pim-1 in the BCR/ABL-mediated leukemogenesis

21 January 2018

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MCL1 transgenic mice exhibit a high incidence of B-cell lymphoma manifested as a spectrum of histologic subtypes.

21 January 2018

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21 January 2018

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Bax suppresses tumorigenesis and stimulates apoptosis in vivo

21 January 2018

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Haploid loss of bax leads to accelerated mammary tumor development in C3(1)/SV40-TAg transgenic mice: reduction in protective apoptotic response at the preneoplastic stage

21 January 2018

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Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

21 January 2018

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Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation.

21 January 2018

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TRAIL-R as a negative regulator of innate immune cell responses.

21 January 2018

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Fas ligand-induced apoptosis

21 January 2018

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Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia

21 January 2018

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FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor

21 January 2018

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21 January 2018

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Differential inactivation of caspase-8 in lung cancers.

21 January 2018

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21 January 2018

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21 January 2018

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A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

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BID regulation by p53 contributes to chemosensitivity

21 January 2018

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Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity

21 January 2018

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Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

21 January 2018

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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PUMA induces the rapid apoptosis of colorectal cancer cells

21 January 2018

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PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

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21 January 2018

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Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

21 January 2018

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BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo.

21 January 2018

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p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation

21 January 2018

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Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells

21 January 2018

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p53 mutations in human cancers

21 January 2018

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Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

21 January 2018

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Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

21 January 2018

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

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Tumor spectrum analysis in p53-mutant mice

21 January 2018

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Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

21 January 2018

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Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

21 January 2018

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Dissecting p53 tumor suppressor functions in vivo

21 January 2018

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c-Myc Augments Gamma Irradiation-Induced Apoptosis by Suppressing Bcl-XL

21 January 2018

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Bim is a suppressor of Myc-induced mouse B cell leukemia

21 January 2018

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Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

21 January 2018

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Suppression of tumorigenesis by the p53 target PUMA

21 January 2018

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Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy.

21 January 2018

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Hypoxia and defective apoptosis drive genomic instability and tumorigenesis

21 January 2018

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AP-1: a double-edged sword in tumorigenesis

21 January 2018

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Cloning of a highly conserved human protein serine-threonine phosphatase gene from the glioma candidate region on chromosome 19q13.3.

21 January 2018

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PUMA in head and neck cancer

21 January 2018

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Malignant melanoma: modern black plague and genetic black box.

21 January 2018

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Mutational analysis of Noxa gene in human cancers

21 January 2018

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The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

21 January 2018

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Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

21 January 2018

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Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim.

21 January 2018

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Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants

21 January 2018

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Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

21 January 2018

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Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM.

21 January 2018

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Roles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors

21 January 2018

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Identification of glucocorticoid-response genes in children with acute lymphoblastic leukemia

21 January 2018

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Histone deacetylase inhibitors FK228, N-(2-aminophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)amino- methyl]benzamide and m-carboxycinnamic acid bis-hydroxamide augment radiation-induced cell death in gastrointestinal adenocarcinoma cells

21 January 2018

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Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim.

21 January 2018

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Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis

21 January 2018

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Expression and transcriptional regulation of functionally distinct Bmf isoforms in B-chronic lymphocytic leukemia cells

21 January 2018

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Bmf is a possible mediator in histone deacetylase inhibitors FK228 and CBHA-induced apoptosis

21 January 2018

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Proapoptotic BH3-only Bcl-2 family member Bik/Blk/Nbk is expressed in hemopoietic and endothelial cells but is redundant for their programmed death

21 January 2018

1 reference

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Concomitant loss of proapoptotic BH3-only Bcl-2 antagonists Bik and Bim arrests spermatogenesis

21 January 2018

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Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma.

21 January 2018

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Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53.

21 January 2018

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Mutations of the BIK gene in human peripheral B-cell lymphomas

21 January 2018

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High-resolution genome-wide mapping of genetic alterations in human glial brain tumors

21 January 2018

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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Regulation of PTEN transcription by p53

21 January 2018

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Bad-deficient mice develop diffuse large B cell lymphoma

21 January 2018

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The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells

21 January 2018

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Inactivating mutations of proapoptotic Bad gene in human colon cancers

21 January 2018

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Molecular cloning of a novel polypeptide, DP5, induced during programmed neuronal death

21 January 2018

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The cell death-promoting gene DP5, which interacts with the BCL2 family, is induced during neuronal apoptosis following exposure to amyloid beta protein

21 January 2018

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Brain ischemia/reperfusion-induced expression of DP5 and its interaction with Bcl-2, thus freeing Bax from Bcl-2/Bax dimmers are mediated by c-Jun N-terminal kinase (JNK) pathway

21 January 2018

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Critical role for DP5/Harakiri, a Bcl-2 homology domain 3-only Bcl-2 family member, in axotomy-induced neuronal cell death.

21 January 2018

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harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)

21 January 2018

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Frequent HRK inactivation associated with low apoptotic index in secondary glioblastomas.

21 January 2018

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An inhibitor of Bcl-2 family proteins induces regression of solid tumours

21 January 2018

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Different cooperating effect of p21 or p27 deficiency in combination with INK4a/ARF deletion in mice

21 January 2018

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Is Apaf-1 expression frequently abrogated in melanoma?

21 January 2018

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Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

21 January 2018

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7 January 2021

Expression and function of the apoptosis effector Apaf-1 in melanoma

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7 January 2021

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

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7 January 2021

Expression of the proapoptotic protein Bid is an adverse prognostic factor for radiotherapy outcome in carcinoma of the cervix.

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7 January 2021

Molecular cloning and characterization of a cDNA for a novel phorbol-12-myristate-13-acetate-responsive gene that is highly expressed in an adult T-cell leukemia cell line

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7 January 2021

Essential role for the BH3-only protein Bim but redundant roles for Bax, Bcl-2, and Bcl-w in the control of granulocyte survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401940

7 January 2021

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401940

7 January 2021

Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401940

7 January 2021

B-cell lymphoma-associated hemophagocytic syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401940

7 January 2021

PUMA expression is significantly reduced in human cutaneous melanomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401940

7 January 2021