(Q40128908)

17 September 2017

1 reference

title

The LDL receptor defect in familial hypercholesterolemia. Implications for pathogenesis and therapy (English)

1 reference

17 September 2017

The LDL Receptor Defect in Familial Hypercholesterolemia: Implications for Pathogenesis and Therapy (English)

1 reference

https://api.crossref.org/works/10.1016/S0025-7125(16)31424-9

15 September 2023

0 references

1

J L Goldstein

1 reference

17 September 2017

M. S. Brown

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6279983

15 September 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=6279983

15 September 2023

publication date

1 March 1982

1 reference

full work available at URL

17 September 2017

https://api.elsevier.com/content/article/PII:S0025712516314249?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S0025-7125(16)31424-9

https://api.elsevier.com/content/article/PII:S0025712516314249?httpAccept=text/plain

15 September 2023

1 reference

https://api.crossref.org/works/10.1016/S0025-7125(16)31424-9

Medical Clinics of North America

15 September 2023

published in

1 reference

17 September 2017

volume

66

1 reference

17 September 2017

issue

2

1 reference

17 September 2017

page(s)

335-362

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Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent

17 September 2017

cites work

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Evidence for regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol synthesis in nonhepatic tissues of rat

15 September 2023

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Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts

15 September 2023

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Reduction in cholesterol and low density lipoprotein synthesis after portacaval shunt surgery in a patient with homozygous familial hypercholesterolemia

15 September 2023

9

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Genetics of the low density lipoprotein receptor. Diminished receptor activity in lymphocytes from heterozygotes with familial hypercholesterolemia

15 September 2023

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Metabolic studies in familial hypercholesterolemia. Evidence for a gene-dosage effect in vivo

15 September 2023

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The scavenger cell pathway for lipoprotein degradation: Specificity of the binding site that mediates the uptake of negatively-charged LDL by macrophages

15 September 2023

12

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Familial hypercholesterolemia: model for genetic receptor disease

15 September 2023

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Regulation of the activity of the low density lipoprotein receptor in human fibroblasts

15 September 2023

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Reversible accumulation of cholesteryl esters in macrophages incubated with acetylated lipoproteins

15 September 2023

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Evolution of the LDL receptor concept-from cultured cells to intact animals

15 September 2023

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Receptor-Mediated Uptake of Lipoprotein-Cholesterol and Its Utilization for Steroid Synthesis in the Adrenal Cortex

15 September 2023

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Regulation of plasma cholesterol by lipoprotein receptors

15 September 2023

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Prenatal diagnosis of homozygous familial hypercholesterolaemia. Expression of a genetic receptor disease in utero

15 September 2023

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Cellular pathology of homozygous familial hypercholesterolemia

15 September 2023

22

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Regulatory role of triiodothyronine in the degradation of low density lipoprotein by cultured human skin fibroblasts

15 September 2023

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Autoradiographic localization of the sites of uptake, cellular transport, and catabolism of low density lipoproteins in the liver of normal and estrogen-treated rats

15 September 2023

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Regulation of cholesterol metabolism. I.

15 September 2023

27

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Monacolin K, a new hypocholesterolemic agent produced by a Monascus species.

15 September 2023

29

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Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity

15 September 2023

30

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Malondialdehyde alteration of low density lipoproteins leads to cholesteryl ester accumulation in human monocyte-macrophages

15 September 2023

31

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Coated pits, coated vesicles, and receptor-mediated endocytosis

15 September 2023

33

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Atherosclerosis: The low-density lipoprotein receptor hypothesis

15 September 2023

34

1 reference

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Familial hypercholesterolemia. A genetic regulatory defect in cholesterol metabolism

15 September 2023

36

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Familial hypercholesterolemia: pathogenesis of a receptor disease

15 September 2023

37

1 reference

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The LDL receptor locus and the genetics of familial hypercholesterolemia

15 September 2023

38

1 reference

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The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

15 September 2023

39

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Demonstration of low density lipoprotein receptors in mouse teratocarcinoma stem cells and description of a method for producing receptor-deficient mutant mice

15 September 2023

40

1 reference

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Genetics of the LDL receptor: Evidence that the mutations affecting binding and internalization are allelic

15 September 2023

41

1 reference

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Genetic heterogeneity in familial hypercholesterolemia: evidence for two different mutations affecting functions of low-density lipoprotein receptor

15 September 2023

42

1 reference

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Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

15 September 2023

43

1 reference

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Heterozygous familial hypercholesterolemia: Failure of normal allele to compensate for mutant allele at a regulated genetic locus

15 September 2023

45

1 reference

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Effects of ML-236B (Compactin) on Sterol Synthesis and Low Density Lipoprotein Receptor Activities in Fibroblasts of Patients with Homozygous Familial Hypercholesterolemia

15 September 2023

47

1 reference

https://api.crossref.org/works/10.1016/S0025-7125(16)31424-9

Lipoproteins and Lipid Transport

15 September 2023

48

1 reference

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Regulation of low density lipoprotein receptor activity in freshly isolated human lymphocytes

15 September 2023

49

1 reference

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Receptor binding of cholesterol-induced high-density lipoproteins containing predominantly apoprotein E to cultured fibroblasts with mutations at the low-density lipoprotein receptor locus

15 September 2023

52

1 reference

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Deficiency of low density lipoprotein receptors in liver and adrenal gland of the WHHL rabbit, an animal model of familial hypercholesterolemia

15 September 2023

54

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Low Density Lipoprotein Receptors in Bovine Adrenal Cortex. II. Low Density Lipoprotein Binding to Membranes Prepared from Fresh Tissue*

15 September 2023

55

1 reference

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Regulatory role for hepatic low density lipoprotein receptors in vivo in the dog

15 September 2023

56

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Saturation and suppression of hepatic lipoprotein receptors: a mechanism for the hypercholesterolemia of cholesterol-fed rabbits

15 September 2023

57

1 reference

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Reconstituted low density lipoprotein: A vehicle for the delivery of hydrophobic fluorescent probes to cells

15 September 2023

60

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The metabolism of low density lipoprotein in familial type II hyperlipoproteinemia

15 September 2023

61

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Properties of Lipoproteins Responsible for High Affinity Binding to Cell Surface Receptors of Fibroblasts and Smooth Muscle Cells

15 September 2023

63

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Cholesteryl ester synthesis in macrophages: stimulation by beta-very low density lipoproteins from cholesterol-fed animals of several species

15 September 2023

64

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Homozygous familial hypercholesterolemia mutant with a defect in internalization of low density lipoprotein

15 September 2023

66

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The effect of cholestyramine on the faecal excretion of bile acids and neutral steroids in familial hypercholesterolaemia

15 September 2023

67

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Low density lipoprotein metabolism in a family of familial hypercholesterolemic patients

15 September 2023

68

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Tissue sites of degradation of low density lipoprotein: Application of a method for determining the fate of plasma proteins

15 September 2023

70

1 reference

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Solubilization of the low density lipoprotein receptor

15 September 2023

73

1 reference

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Elevated Cholesterol and Bile Acid Synthesis in a Young Patient with Homozygous Familial Hypercholesterolemia

15 September 2023

76

1 reference

https://api.crossref.org/works/10.1016/S0025-7125(16)31424-9

Cholestyramine promotes receptor-mediated low-density-lipoprotein catabolism

15 September 2023

78

1 reference

https://api.crossref.org/works/10.1016/S0025-7125(16)31424-9

The metabolism of the apoprotein of plasma low density lipoprotein in familial hype rbetalipoproteinaemia in the homozygous form

15 September 2023

80

1 reference

https://api.crossref.org/works/10.1016/S0025-7125(16)31424-9

Malondialdehyde formation as an indicator of prostaglandin production by human platelets

15 September 2023

83

1 reference

https://api.crossref.org/works/10.1016/S0025-7125(16)31424-9

Simultaneous measurement of apolipoprotein B turnover in very-low- and low-density lipoproteins in familial hypercholesterolaemia

15 September 2023

84

1 reference

https://api.crossref.org/works/10.1016/S0025-7125(16)31424-9

Lipoprotein-acid mucopolysaccharide complexes of human atherosclerotic lesions

15 September 2023

85

1 reference

https://api.crossref.org/works/10.1016/S0025-7125(16)31424-9

WHHL-rabbit: a low density lipoprotein receptor-deficient animal model for familial hypercholesterolemia

15 September 2023

87

1 reference

https://api.crossref.org/works/10.1016/S0025-7125(16)31424-9

Serial inbreeding of rabbits with hereditary hyperlipidemia (WHHL-rabbit).

15 September 2023

90

1 reference

https://api.crossref.org/works/10.1016/S0025-7125(16)31424-9

Therapeutic effects of ML-236B in primary hypercholesterolemia

15 September 2023

93

1 reference

https://api.crossref.org/works/10.1016/S0025-7125(16)31424-9

15 September 2023

Identifiers

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=6279983

15 September 2023

1 reference