(Q40130034)

17 September 2017

title

Targeting calcineurin activation as a therapeutic strategy for T-cell acute lymphoblastic leukemia (English)

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17 September 2017

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8

Hugues de Thé

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author name string

Hind Medyouf

1

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17 September 2017

Hélène Alcalde

2

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17 September 2017

Caroline Berthier

3

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17 September 2017

Marie Claude Guillemin

4

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17 September 2017

Nuno R dos Santos

5

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17 September 2017

Anne Janin

6

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17 September 2017

Didier Decaudin

7

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17 September 2017

Jacques Ghysdael

9

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17 September 2017

language of work or name

English

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publication date

21 May 2007

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17 September 2017

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17 September 2017

volume

13

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17 September 2017

issue

6

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17 September 2017

page(s)

736-741

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Calcineurin B1 is essential for positive but not negative selection during thymocyte development

17 September 2017

cites work

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7 January 2021

Defective T cell development and function in calcineurin A beta -deficient mice

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7 January 2021

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

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7 January 2021

Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1.

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7 January 2021

A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

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7 January 2021

Signal transducer and activator of transcription proteins in leukemias.

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7 January 2021

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

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7 January 2021

Transcriptional regulation by calcium, calcineurin, and NFAT

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7 January 2021

NFAT signaling: choreographing the social lives of cells

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7 January 2021

NFAT proteins: key regulators of T-cell development and function

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7 January 2021

Notch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient mice

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7 January 2021

Sensitivity to myc-induced apoptosis is retained in spontaneous and transplanted lymphomas of CD2-mycER mice

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7 January 2021

High efficacy of combined rituximab and gemcitabine on Epstein-Barr virus-associated human B-cell lymphoma obtained after Hodgkin's xenograft in immunodeficient mice

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7 January 2021

Pre-TCR expression cooperates with TEL-JAK2 to transform immature thymocytes and induce T-cell leukemia.

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7 January 2021

Structures of calcineurin and its complexes with immunophilins–immunosuppressants

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7 January 2021

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

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7 January 2021

The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis

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7 January 2021

A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus

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7 January 2021

The role of NFAT transcription factors in integrin-mediated carcinoma invasion

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7 January 2021

A constitutively active NFATc1 mutant induces a transformed phenotype in 3T3-L1 fibroblasts

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7 January 2021

The NFATc1 transcription factor is widely expressed in white cells and translocates from the cytoplasm to the nucleus in a subset of human lymphomas

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7 January 2021

Constitutive NF-kappaB and NFAT activation in aggressive B-cell lymphomas synergistically activates the CD154 gene and maintains lymphoma cell survival

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7 January 2021

Overexpression of c-myc in pancreatic cancer caused by ectopic activation of NFATc1 and the Ca2+/calcineurin signaling pathway

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7 January 2021

Extended follow-up of long-term survivors of childhood acute lymphoblastic leukemia

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7 January 2021

Advances in the biology and therapy of diffuse large B-cell lymphoma: moving toward a molecularly targeted approach

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7 January 2021

Plat-E: an efficient and stable system for transient packaging of retroviruses

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7 January 2021

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

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7 January 2021

Vascular endothelial growth factor-A is expressed both on lymphoma cells and endothelial cells in angioimmunoblastic T-cell lymphoma and related to lymphoma progression.

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7 January 2021

Alternative polyadenylation events contribute to the induction of NF-ATc in effector T cells

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7 January 2021

Identifiers

DOI

10.1038/NM1588

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17 September 2017

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