(Q40130656)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17512966%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

title

Structure-based discovery of a new class of Bcl-xL antagonists (English)

1 reference

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30 December 2019

2

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30 December 2019

author name string

Michele F Rega

1

1 reference

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30 December 2019

Dawoon Jung

3

1 reference

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30 December 2019

Naomi J H Cotton

4

1 reference

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30 December 2019

John L Stebbins

5

1 reference

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30 December 2019

Maurizio Pellecchia

6

1 reference

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30 December 2019

publication date

21 May 2007

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30 December 2019

1 reference

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30 December 2019

volume

35

1 reference

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30 December 2019

issue

4

1 reference

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30 December 2019

page(s)

344-353

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17512966%20AND%20SRC:MED&resulttype=core&format=json

Structure-based design of potent small-molecule inhibitors of anti-apoptotic Bcl-2 proteins

30 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

A structure-based approach to retinoid X receptor-alpha inhibition.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

Discovery and structure-activity relationship of antagonists of B-cell lymphoma 2 family proteins with chemopotentiation activity in vitro and in vivo

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

Solution nuclear magnetic resonance spectroscopy techniques for probing intermolecular interactions

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

Apoptosis-based therapies for hematologic malignancies

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

Inhibition of anti-apoptotic Bcl-2 family proteins by natural polyphenols: new avenues for cancer chemoprevention and chemotherapy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

Rational design and real time, in-cell detection of the proapoptotic activity of a novel compound targeting Bcl-X(L).

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

Cancer prevention by tea polyphenols is linked to their direct inhibition of antiapoptotic Bcl-2-family proteins.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

Apoptosis: a link between cancer genetics and chemotherapy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

Discovery of a potent inhibitor of the antiapoptotic protein Bcl-xL from NMR and parallel synthesis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

Development of a potent Bcl-x(L) antagonist based on alpha-helix mimicry

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2023964

Deconstructing fragment-based inhibitor discovery

20 August 2018

1 reference

12 December 2020

Synthesis of tetrocarcin derivatives with specific inhibitory activity towards Bcl-2 functions

1 reference

12 December 2020

Cell Death in Development

1 reference

12 December 2020

Comparison of chemical inhibitors of antiapoptotic Bcl-2-family proteins

1 reference

12 December 2020

10.1016/J.BIOORG.2007.03.001

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17512966%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17512966%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

PubMed publication ID

17512966

1 reference