(Q40133028)

17 September 2017

Cloning and characterization of a functional human gamma-aminobutyric acid (GABA) transporter, human GAT-2. (English)

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17 September 2017

4

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17 September 2017

3

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author name string

Bolette Christiansen

series ordinal

1

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PubMed ID

17502375

17 September 2017

Anne-Kristine Meinild

series ordinal

2

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PubMed ID

17502375

17 September 2017

language of work or name

English

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publication date

14 May 2007

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Journal of Biological Chemistry

17 September 2017

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17 September 2017

282

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17 September 2017

27

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17 September 2017

19331-19341

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The action of gamma-aminobutyric acid on cortical neurones

17 September 2017

1 reference

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GABA and glycine as neurotransmitters: a brief history

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GABA-based therapeutic approaches: GABAA receptor subtype functions

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Molecular structure and physiological functions of GABA(B) receptors

21 January 2018

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Uptake and metabolism of γ-aminobutyric acid by neurones and glial cells

21 January 2018

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Cloning and expression of a rat brain GABA transporter

21 January 2018

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Cloning of the human brain GABA transporter

21 January 2018

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Molecular cloning and functional characterization of a GABA/betaine transporter from human kidney

21 January 2018

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A liver-specific isoform of the betaine/GABA transporter in the rat: cDNA sequence and organ distribution.

21 January 2018

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Synaptic uptake and beyond: the sodium- and chloride-dependent neurotransmitter transporter family SLC6

21 January 2018

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Neurotransmitter transporters: molecular function of important drug targets

21 January 2018

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Role of Cl- in electrogenic Na+-coupled cotransporters GAT1 and SGLT1.

21 January 2018

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Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

21 January 2018

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Neurotransmitter transporters and their impact on the development of psychopharmacology

21 January 2018

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GABAergic mechanisms in epilepsy

21 January 2018

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GABA puts a stop to pain.

21 January 2018

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GABA uptake inhibitors: relevance to antiepileptic drug research

21 January 2018

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GABA transporter heterogeneity: pharmacology and cellular localization

21 January 2018

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The inhibitory neural circuitry as target of antiepileptic drugs

21 January 2018

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Reversal or reduction of glutamate and GABA transport in CNS pathology and therapy.

21 January 2018

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Tiagabine for the treatment of anxiety

21 January 2018

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The GABA uptake inhibitor tiagabine promotes slow wave sleep in normal elderly subjects

21 January 2018

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Inhibition of gamma-aminobutyric acid uptake: anatomy, physiology and effects against epileptic seizures

21 January 2018

1 reference

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Anticonvulsant properties of two GABA uptake inhibitors NNC 05-2045 and NNC 05-2090, not acting preferentially on GAT-1.

21 January 2018

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A novel selective gamma-aminobutyric acid transport inhibitor demonstrates a functional role for GABA transporter subtype GAT2/BGT-1 in the CNS.

21 January 2018

1 reference

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Role of the betaine/GABA transporter (BGT-1/GAT2) for the control of epilepsy

21 January 2018

1 reference

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First demonstration of a functional role for central nervous system betaine/{gamma}-aminobutyric acid transporter (mGAT2) based on synergistic anticonvulsant action among inhibitors of mGAT1 and mGAT2.

21 January 2018

1 reference

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GABA transporters and GABA-transaminase as drug targets

21 January 2018

1 reference

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Sequence and chromosomal assignment of a human novel cDNA: similarity to gamma-aminobutyric acid transporter

21 January 2018

1 reference

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A novel class of conformationally restricted heterocyclic muscarinic agonists

21 January 2018

1 reference

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Selective inhibitors of GABA uptake: synthesis and molecular pharmacology of 4-N-methylamino-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-ol analogues

21 January 2018

1 reference

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The human Na+-glucose cotransporter is a molecular water pump.

21 January 2018

1 reference

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Functional expression and properties of the human skeletal muscle sodium channel

21 January 2018

1 reference

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Pharmacological characterization of human excitatory amino acid transporters EAAT1, EAAT2 and EAAT3 in a fluorescence-based membrane potential assay

21 January 2018

1 reference

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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

21 January 2018

1 reference

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The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression

21 January 2018

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The repertoire of solute carriers of family 6: identification of new human and rodent genes.

21 January 2018

1 reference

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Presteady-state and steady-state kinetics and turnover rate of the mouse gamma-aminobutyric acid transporter (mGAT3).

21 January 2018

1 reference

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Novel parent structures for inhibitors of the murine GABA transporters mGAT3 and mGAT4.

21 January 2018

1 reference

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Design, synthesis and evaluation of substituted triarylnipecotic acid derivatives as GABA uptake inhibitors: identification of a ligand with moderate affinity and selectivity for the cloned human GABA transporter GAT-3.

21 January 2018

1 reference

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Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1.

21 January 2018

1 reference

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Action of bicyclic isoxazole GABA analogues on GABA transporters and its relation to anticonvulsant activity

21 January 2018

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GABA transporters as drug targets for modulation of GABAergic activity

21 January 2018

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1-(3-(9H-carbazol-9-yl)-1-propyl)-4-(2-methoxyphenyl)-4-piperidinol, a novel subtype selective inhibitor of the mouse type II GABA-transporter

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M702111200

1 reference

17 September 2017

1 reference

PubMed ID

17502375