(Q40140570)

17 September 2017

title

Membrane expression of DR4, DR5 and caspase-8 levels, but not Mcl-1, determine sensitivity of human myeloma cells to Apo2L/TRAIL. (English)

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17 September 2017

Maria Gómez-Benito

1

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17 September 2017

Maria José Martinez-Lorenzo

2

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17 September 2017

Alberto Anel

3

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17 September 2017

Isabel Marzo

4

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17 September 2017

Javier Naval

5

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17 September 2017

language of work or name

English

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publication date

30 March 2007

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Experimental Cell Research

17 September 2017

published in

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17 September 2017

volume

313

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17 September 2017

issue

11

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17 September 2017

page(s)

2378-2388

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Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development

17 September 2017

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TRAIL is a potent inducer of apoptosis in myeloma cells derived from multiple myeloma patients and is not cytotoxic to hematopoietic stem cells

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TRAIL-induced eradication of primary tumour cells from multiple myeloma patient bone marrows is not related to TRAIL receptor expression or prior chemotherapy

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Mcl-1L cleavage is involved in TRAIL-R1- and TRAIL-R2-mediated apoptosis induced by HGS-ETR1 and HGS-ETR2 human mAbs in myeloma cells

7 January 2021

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Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells.

7 January 2021

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TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: therapeutic applications

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way.

7 January 2021

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Apo2L/TRAIL is an indirect mediator of apoptosis induced by interferon-alpha in human myeloma cells

7 January 2021

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Growth factors and antiapoptotic signaling pathways in multiple myeloma

7 January 2021

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Differential effects of filipin and methyl-beta-cyclodextrin on B cell receptor signaling

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Amiloride augments TRAIL-induced apoptotic death by inhibiting phosphorylation of kinases and phosphatases associated with the P13K-Akt pathway

7 January 2021

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Temperature-sensitive differential affinity of TRAIL for its receptors. DR5 is the highest affinity receptor

7 January 2021

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The short splice form of Casper/c-FLIP is a major cellular inhibitor of TRAIL-induced apoptosis.

7 January 2021

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TCR-mediated up-regulation of c-FLIPshort correlates with resistance toward CD95-mediated apoptosis by blocking death-inducing signaling complex activity

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.018

Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

7 January 2021

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Regulation of lymphocyte proliferation and death by FLIP.

7 January 2021

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c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis

7 January 2021

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Cellular FLIP long form augments caspase activity and death of T cells through heterodimerization with and activation of caspase-8.

7 January 2021

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The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex

7 January 2021

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The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases

7 January 2021

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Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells

7 January 2021

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Depsipeptide (FR901228) enhances the cytotoxic activity of TRAIL by redistributing TRAIL receptor to membrane lipid rafts

7 January 2021

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7 January 2021

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Valproic acid inhibits angiogenesis in vitro and in vivo

7 January 2021

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IFNalpha-stimulated neutrophils and monocytes release a soluble form of TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) displaying apoptotic activity on leukemic cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.018

Myeloid cell factor-1 is a critical survival factor for multiple myeloma

7 January 2021

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Mechanism of apoptosis induced by IFN-alpha in human myeloma cells: role of Jak1 and Bim and potentiation by rapamycin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.018

10.1016/J.YEXCR.2007.03.018

7 January 2021

Identifiers

DOI

1 reference

17 September 2017

1 reference