(Q40170517)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

Subunit-specific mechanisms and proton sensitivity of NMDA receptor channel block (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

7

1 reference

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25 December 2019

author name string

Shashank M Dravid

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Kevin Erreger

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Hongjie Yuan

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Katherine Nicholson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Phuong Le

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Polina Lyuboslavsky

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Ernest Murray

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Cara Mosely

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Jeremy Barber

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Adam French

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Robert Balster

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Thomas F Murray

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Stephen F Traynelis

14

1 reference

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25 December 2019

language of work or name

English

0 references

publication date

15 February 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

number of pages

22

1 reference

inferred from page(s)

published in

Journal of Physiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

volume

581

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

issue

Pt 1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

page(s)

107-128

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

N-methyl-D-aspartate antagonists: ready for clinical trial in brain ischemia?

25 December 2019

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Permeant ion regulation of N-methyl-D-aspartate receptor channel block by Mg(2+).

21 January 2018

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Drug abuse potential evaluation in animals

21 January 2018

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Protons trap NR1/NR2B NMDA receptors in a nonconducting state.

21 January 2018

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Amantadine inhibits NMDA receptors by accelerating channel closure during channel block.

21 January 2018

1 reference

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Determinants of trapping block of N-methyl-d-aspartate receptor channels.

21 January 2018

1 reference

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The behavior of 9-aminoacridine as an indicator of transmembrane pH difference in liposomes of natural bacterial phospholipids

21 January 2018

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Modulation of pH by neuronal activity

21 January 2018

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Glutamate neurotoxicity in cortical cell culture is calcium dependent

21 January 2018

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21 January 2018

Excitotoxic cell death

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Identification and mechanism of action of two histidine residues underlying high-affinity Zn2+ inhibition of the NMDA receptor

21 January 2018

1 reference

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NMDA receptor NR2 subunit dependence of the slow component of magnesium unblock.

21 January 2018

1 reference

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Open channel block and alteration of N-methyl-D-aspartic acid receptor gating by an analog of phencyclidine

21 January 2018

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Pathobiology of ischaemic stroke: an integrated view

21 January 2018

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Brevetoxin activation of voltage-gated sodium channels regulates Ca dynamics and ERK1/2 phosphorylation in murine neocortical neurons

21 January 2018

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Memantine is highly potent in protecting cortical cultures against excitotoxic cell death evoked by glutamate and N-methyl-D-aspartate

21 January 2018

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Glutamate receptor gating.

21 January 2018

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Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles.

21 January 2018

1 reference

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Mechanism of partial agonism at NMDA receptors for a conformationally restricted glutamate analog.

21 January 2018

1 reference

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Influence of urine pH and urinary flow on the renal excretion of memantine

21 January 2018

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Effects of MK-801 stereoisomers on schedule-controlled behavior in rats

21 January 2018

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Dizocilpine-like discriminative stimulus effects of competitive NMDA receptor antagonists in mice.

21 January 2018

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Acidosis reduces NMDA receptor activation, glutamate neurotoxicity, and oxygen-glucose deprivation neuronal injury in cortical cultures

21 January 2018

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The mechanism of action and pharmacological specificity of the anticonvulsant NMDA antagonist MK-801: a voltage clamp study on neuronal cells in culture

21 January 2018

1 reference

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Evaluation of the NR2B-selective NMDA receptor antagonist Ro 63-1908 on rodent behaviour: evidence for an involvement of NR2B NMDA receptors in response inhibition

21 January 2018

1 reference

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The pH-dependent rate of action of local anesthetics on the node of Ranvier

21 January 2018

1 reference

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Comparison of the behavioral and biochemical effects of the NMDA receptor antagonists, MK-801 and phencyclidine

21 January 2018

1 reference

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Caffeine as a model drug of abuse

21 January 2018

1 reference

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Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels

21 January 2018

1 reference

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High probability opening of NMDA receptor channels by L-glutamate

21 January 2018

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Glutamate receptor subunit expression in primary neuronal and secondary glial cultures

21 January 2018

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Mechanism of action of memantine

21 January 2018

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NMDA antagonist inhibits rapid tolerance to ethanol

21 January 2018

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Pharmacologic Studies of the Neuroprotective Actions of a Glutamate Antagonist in Ischemia

21 January 2018

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The changing landscape of ischaemic brain injury mechanisms.

21 January 2018

1 reference

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Differential binding properties of [3H]dextrorphan and [3H]MK-801 in heterologously expressed NMDA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Developmental changes in localization of NMDA receptor subunits in primary cultures of cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Molecular determinants of proton-sensitive N-methyl-D-aspartate receptor gating.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Molecular determinants of coordinated proton and zinc inhibition of N-methyl-D-aspartate NR1/NR2A receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Actions of ketamine, phencyclidine and MK-801 on NMDA receptor currents in cultured mouse hippocampal neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Mechanisms of blockade of excitatory amino acid receptor channels

21 January 2018

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Glutamate receptors and transporters in genetic and acquired models of epilepsy

21 January 2018

1 reference

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Identification by mutagenesis of a Mg(2+)-block site of the NMDA receptor channel

21 January 2018

1 reference

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Phenylethanolamines inhibit NMDA receptors by enhancing proton inhibition

21 January 2018

1 reference

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Open probability of homomeric murine 5-HT3A serotonin receptors depends on subunit occupancy

21 January 2018

1 reference

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Evaluation of the reinforcing properties and phencyclidine-like discriminative stimulus effects of dextromethorphan and dextrorphan in rats and rhesus monkeys

21 January 2018

1 reference

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Is high extracellular glutamate the key to excitotoxicity in traumatic brain injury?

21 January 2018

1 reference

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Influence of extracellular pH on inhibition by ifenprodil at N-methyl-D-aspartate receptors in Xenopus oocytes

21 January 2018

1 reference

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Patch clamp studies on the kinetics and selectivity of N-methyl-D-aspartate receptor antagonism by memantine (1-amino-3,5-dimethyladamantan).

21 January 2018

1 reference

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Structural locus of the pH gate in the Kir1.1 inward rectifier channel.

21 January 2018

1 reference

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Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death

21 January 2018

1 reference

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pH gating of ROMK (K(ir)1.1) channels: control by an Arg-Lys-Arg triad disrupted in antenatal Bartter syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Local anesthetics. Effect of pH on use-dependent block of sodium channels in frog muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Blocker studies of the functional architecture of the NMDA receptor channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Modulation of the N-methyl-D-aspartate channel by extracellular H+

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Evolving concepts about the role of acidosis in ischemic neuropathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Pharmacological properties and H+ sensitivity of excitatory amino acid receptor channels in rat cerebellar granule neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

The behavioural effects of MK-801: a comparison with antagonists acting non-competitively and competitively at the NMDA receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

The effect of external pH changes on responses to excitatory amino acids in mouse hippocampal neurones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

NMDA/NR2B selective antagonists in the treatment of ischemic brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Discriminative stimulus effects of site-selective N-methyl-D-aspartate antagonists in NPC 17742-trained rats and squirrel monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Phencyclidine-like discriminative stimulus properties of MK-801 in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Intracellular Mg2+ interacts with structural determinants of the narrow constriction contributed by the NR1-subunit in the NMDA receptor channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

A single residue contributes to the difference between Kir4.1 and Kir1.1 channels in pH sensitivity, rectification and single channel conductance

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Biophysical and molecular mechanisms underlying the modulation of heteromeric Kir4.1-Kir5.1 channels by CO2 and pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Conserved structural and functional control of N-methyl-D-aspartate receptor gating by transmembrane domain M3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Allosteric interaction between the amino terminal domain and the ligand binding domain of NR2A.

21 January 2018

1 reference

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Na(+) occupancy and Mg(2+) block of the n-methyl-d-aspartate receptor channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

The N-methyl-d-aspartate antagonists phencyclidine, ketamine and dizocilpine as both behavioral and anatomical models of the dementias

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

Phencyclidine - Effects on Human Performance and Behavior.

21 January 2018

1 reference

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N-methyl-D-aspartate receptor channel block by meperidine is dependent on extracellular pH.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075223

Probing of NMDA channels with fast blockers

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075223

Characterization of MK-801-induced behavior as a putative rat model of psychosis

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075223

The glutamate receptor ion channels

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075223

Molecular determinants of NMDA receptor pharmacological diversity

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075223

Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075223

Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075223

NR1 and NR2 subunit contributions to N-methyl-D-aspartate receptor channel blocker pharmacology

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075223

A review of NMDA receptors and the phencyclidine model of schizophrenia

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075223

Amantadine and memantine are NMDA receptor antagonists with neuroprotective properties.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075223

Structural basis for explaining open-channel blockade of the NMDA receptor.

4 November 2018

1 reference

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Transport of amantadine and rimantadine through the blood-brain barrier

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075223

Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075223

Receptor mediation of the discriminative stimulus properties of phencyclidine and sigma-opioid agonists.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075223

The neuroprotective action of ketamine and MK-801 after transient cerebral ischemia in rats.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075223

N-methyl-D-aspartate antagonism and phencyclidine-like activity: a drug discrimination analysis

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075223

4 November 2018

1 reference

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Dynamics of interstitial and intracellular pH in evolving brain infarct

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075223

Single-channel conductances of NMDA receptors expressed from cloned cDNAs: comparison with native receptors

4 November 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2006.124958

The glutamate antagonist MK-801 reduces focal ischemic brain damage in the rat

21 January 2018

1 reference

12 December 2020

Effect of extracellular pH on the potency of N-methyl-D-aspartic acid receptor competitive antagonists

1 reference

12 December 2020

Block and modulation of N-methyl-D-aspartate receptors by polyamines and protons: role of amino acid residues in the transmembrane and pore-forming regions of NR1 and NR2 subunits

1 reference

12 December 2020

Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay

1 reference

12 December 2020

Trapping channel block of NMDA-activated responses by amantadine and memantine

1 reference

12 December 2020

Control of rat GluR6 glutamate receptor open probability by protein kinase A and calcineurin

1 reference

12 December 2020

pH-metric log P. 4. Comparison of partition coefficients determined by HPLC and potentiometric methods to literature values

1 reference

12 December 2020

Dynamics of the actions of tetrahydro-9-aminoacridine and 9-aminoacridine on glutamatergic currents: concentration-jump studies in cultured rat hippocampal neurons

1 reference

12 December 2020

Binding sites for permeant ions in the channel of NMDA receptors and their effects on channel block

1 reference

12 December 2020

In vivo demonstration of the enhancement of MK-801 by L-glutamate

1 reference

12 December 2020

Memantine is a potent blocker of N-methyl-D-aspartate (NMDA) receptor channels

1 reference

12 December 2020

10.1113/JPHYSIOL.2006.124958

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303642%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

PMC publication ID

2075223

0 references

1 reference