(Q40178575)

18 September 2017

The role of chrysin and the ah receptor in induction of the human UGT1A1 gene in vitro and in transgenic UGT1 mice (English)

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18 September 2017

Jessica A Bonzo

1

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18 September 2017

Alain Bélanger

series ordinal

2

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18 September 2017

Robert H Tukey

series ordinal

3

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18 September 2017

language of work or name

English

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publication date

1 February 2007

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18 September 2017

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18 September 2017

45

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18 September 2017

2

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18 September 2017

349-360

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Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context

18 September 2017

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Identification of transactivation and repression functions of the dioxin receptor and its basic helix-loop-helix/PAS partner factor Arnt: inducible versus constitutive modes of regulation

21 January 2018

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Disposition and metabolism of the flavonoid chrysin in normal volunteers

21 January 2018

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A pharmacokinetic and pharmacodynamic analysis of CPT-11 and its active metabolite SN-38.

21 January 2018

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Dietary flavonoids: effects on xenobiotic and carcinogen metabolism

21 January 2018

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7 January 2021

Mechanisms of induction of enzymes that protect against chemical carcinogenesis

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7 January 2021

Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity

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7 January 2021

Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios

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7 January 2021

Substrate specificity of human hepatic udp-glucuronosyltransferases

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7 January 2021

Human UDP-glucuronosyltransferases: metabolism, expression, and disease

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7 January 2021

Genetic inheritance of Gilbert's syndrome

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7 January 2021

Clinical pharmacology of camptothecins.

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7 January 2021

Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes

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7 January 2021

Differential UGT1A1 induction by chrysin in primary human hepatocytes and HepG2 Cells

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7 January 2021

The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics

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7 January 2021

Induction of human UDP-glucuronosyltransferase UGT1A1 by flavonoids-structural requirements

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7 January 2021

Induction of UDP-glucuronosyltransferase by the flavonoids chrysin and quercetin in Caco-2 cells

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7 January 2021

Cell-based high-throughput bioassays to assess induction and inhibition of CYP1A enzymes.

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7 January 2021

Effect of chrysin, a flavonoid compound, on the mutagenic activity of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) and benzo(a)pyrene (B(a)P) in bacterial and human hepatoma (HepG2) cells

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7 January 2021

Epigallocatechin gallate inhibits aryl hydrocarbon receptor gene transcription through an indirect mechanism involving binding to a 90 kDa heat shock protein

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7 January 2021

Identification of 3'-methoxy-4'-nitroflavone as a pure aryl hydrocarbon (Ah) receptor antagonist and evidence for more than one form of the nuclear Ah receptor in MCF-7 human breast cancer cells

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7 January 2021

Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation

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7 January 2021

Tissue-specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus.

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7 January 2021

Involvement of the xenobiotic response element (XRE) in Ah receptor-mediated induction of human UDP-glucuronosyltransferase 1A1.

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7 January 2021

Response of human CYP1-luciferase plasmids to 2,3,7,8-tetrachlorodibenzo-p-dioxin and polycyclic aromatic hydrocarbons

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7 January 2021

Arsenite inhibition of CYP1A1 induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin is independent of cell cycle arrest.

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7 January 2021

Activation of the Ah receptor signaling pathway by prostaglandins

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7 January 2021

ERK kinase inhibition stabilizes the aryl hydrocarbon receptor: implications for transcriptional activation and protein degradation

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7 January 2021

Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor

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7 January 2021

Degradation of the basic helix-loop-helix/Per-ARNT-Sim homology domain dioxin receptor via the ubiquitin/proteasome pathway

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7 January 2021

The Jun N-terminal kinase inhibitor SP600125 is a ligand and antagonist of the aryl hydrocarbon receptor

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7 January 2021

Induction of UDP-glucuronosyltransferase UGT1A1 by the flavonoid chrysin in Caco-2 cells--potential role in carcinogen bioinactivation

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7 January 2021

Identification of the metabolites of irinotecan, a new derivative of camptothecin, in rat bile and its biliary excretion

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7 January 2021

Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38).

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7 January 2021

Polymorphisms of UDP-glucuronosyltransferase and pharmacokinetics of irinotecan.

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7 January 2021

A pilot study on the safety of combining chrysin, a non-absorbable inducer of UGT1A1, and irinotecan (CPT-11) to treat metastatic colorectal cancer

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7 January 2021

Identifiers

DOI

10.1002/HEP.21481

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18 September 2017

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