(Q40183559)

18 September 2017

title

The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents (English)

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18 September 2017

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Clark C Chen

1

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18 September 2017

Toshiyasu Taniguchi

series ordinal

2

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18 September 2017

Alan D'Andrea

series ordinal

3

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18 September 2017

publication date

13 January 2007

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Journal of Molecular Medicine

18 September 2017

published in

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18 September 2017

volume

85

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18 September 2017

issue

5

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18 September 2017

page(s)

497-509

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https://scigraph.springernature.com/pub.10.1007/s00109-006-0153-2

18 September 2017

exact match

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cites work

Drug sensitivity spectra in Fanconi anemia lymphoblastoid cell lines of defined complementation groups

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Crossref

https://api.crossref.org/works/10.1007%2FS00109-006-0153-2

Molecular pathogenesis of Fanconi anemia: recent progress

21 January 2018

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12 December 2020

Modulation of mammalian O6-alkylguanine-DNA alkyltransferase in vivo by O6-benzylguanine and its effect on the sensitivity of a human glioma tumor to 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea.

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12 December 2020

Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa).

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12 December 2020

FANCE: the link between Fanconi anaemia complex assembly and activity

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12 December 2020

Curcumin-induced inhibition of cellular reactive oxygen species generation: novel therapeutic implications

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12 December 2020

Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair

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12 December 2020

Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication.

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12 December 2020

Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors

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12 December 2020

A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy.

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12 December 2020

O6-benzylguanine and its role in chemotherapy.

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12 December 2020

Hypomutability in Fanconi anemia cells is associated with increased deletion frequency at the HPRT locus

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12 December 2020

The Fanconi anemia protein, FANCE, promotes the nuclear accumulation of FANCC

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12 December 2020

Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors

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12 December 2020

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

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12 December 2020

Alkylation damage in DNA and RNA--repair mechanisms and medical significance

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12 December 2020

Enforced expression of wild-type p53 curtails the transcription of the O(6)-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents

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12 December 2020

Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents

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12 December 2020

Involvement of the DNA mismatch repair system in antineoplastic drug resistance

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12 December 2020

O 6 -Alkylguanine-DNA Alkyltransferase: A Target for the Modulation of Drug Resistance

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12 December 2020

Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents

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12 December 2020

Pattern of recurrence following local chemotherapy with biodegradable carmustine (BCNU) implants in patients with glioblastoma

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12 December 2020

The basis for current treatment recommendations for malignant gliomas

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12 December 2020

Fanconi's anemia: genetic and molecular aspects of the defect

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12 December 2020

A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma

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12 December 2020

Direct interactions of the five known Fanconi anaemia proteins suggest a common functional pathway

1 reference

12 December 2020

Chemosensitizing tumor cells by targeting the Fanconi anemia pathway with an adenovirus overexpressing dominant-negative FANCA.

1 reference

12 December 2020

S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51

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12 December 2020

Transport mechanism-based drug molecular design: novel camptothecin analogues to circumvent ABCG2-associated drug resistance of human tumor cells

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12 December 2020

Mammalian O6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents

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12 December 2020

Repair kinetics of genomic interstrand DNA cross-links: evidence for DNA double-strand break-dependent activation of the Fanconi anemia/BRCA pathway

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12 December 2020

Clinical relevance of MGMT in the treatment of cancer

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12 December 2020

Biallelic inactivation of BRCA2 in Fanconi anemia

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12 December 2020

Fanconi anemia FANCG protein in mitigating radiation- and enzyme-induced DNA double-strand breaks by homologous recombination in vertebrate cells

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12 December 2020

Methylator resistance mediated by mismatch repair deficiency in a glioblastoma multiforme xenograft.

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12 December 2020

Inhibition of telomerase activity in malignant glioma cells correlates with their sensitivity to temozolomide.

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12 December 2020

Effects of dietary curcumin on glutathione S-transferase and malondialdehyde-DNA adducts in rat liver and colon mucosa: relationship with drug levels

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12 December 2020

Suppression of hREV1 expression reduces the rate at which human ovarian carcinoma cells acquire resistance to cisplatin.

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12 December 2020

The molecular mechanisms for the antitumorigenic effect of curcumin

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12 December 2020

The emerging genetic and molecular basis of Fanconi anaemia

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12 December 2020

Generating mutations but providing chemosensitivity: the role of O6-methylguanine DNA methyltransferase in human cancer

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12 December 2020

Repair of DNA containing O6-alkylguanine

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12 December 2020

Gliadel wafer in initial surgery for malignant glioma: long-term follow-up of a multicenter controlled trial

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12 December 2020

Human REV1 modulates the cytotoxicity and mutagenicity of cisplatin in human ovarian carcinoma cells

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12 December 2020

MGMT: its role in cancer aetiology and cancer therapeutics

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12 December 2020

The p53 and Mdm2 families in cancer.

1 reference

12 December 2020

Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells

1 reference

12 December 2020

The Fanconi Anemia/BRCA pathway: new faces in the crowd

1 reference

12 December 2020

Chemotherapy in adult high-grade glioma: a systematic review and meta-analysis of individual patient data from 12 randomised trials

1 reference

12 December 2020

The p38 Mitogen-Activated Protein Kinase Pathway Links the DNA Mismatch Repair System to the G2 Checkpoint and to Resistance to Chemotherapeutic DNA-Methylating Agents

1 reference

12 December 2020

Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway

1 reference

12 December 2020

Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea.

1 reference

12 December 2020

ATR couples FANCD2 monoubiquitination to the DNA-damage response

1 reference

12 December 2020

MGMT gene silencing and benefit from temozolomide in glioblastoma

1 reference

12 December 2020

Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways

1 reference

12 December 2020

Recent advances in the treatment of malignant astrocytoma

1 reference

12 December 2020

Acquisition of resistance to cisplatin is accompanied by changes in the cellular pharmacology of copper

1 reference

12 December 2020

Sensitization of human carcinoma cells to alkylating agents by small interfering RNA suppression of 3-alkyladenine-DNA glycosylase

1 reference

12 December 2020

MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma

1 reference

12 December 2020

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

1 reference

12 December 2020

An ATR- and BRCA1-mediated Fanconi anemia pathway is required for activating the G2/M checkpoint and DNA damage repair upon rereplication

1 reference

12 December 2020

10.1007/S00109-006-0153-2

Identifiers

DOI

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18 September 2017

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