(Q40185668)

English

Ras/ERK1/2-mediated STAT3 Ser727 phosphorylation by familial medullary thyroid carcinoma-associated RET mutants induces full activation of STAT3 and is required for c-fos promoter activation, cell mitogenicity, and transformation.

scientific article published on 5 January 2007

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scholarly article

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Europe PubMed Central

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23 December 2019

Ras/ERK1/2-mediated STAT3 Ser727 phosphorylation by familial medullary thyroid carcinoma-associated RET mutants induces full activation of STAT3 and is required for c-fos promoter activation, cell mitogenicity, and transformation (English)

1 reference

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23 December 2019

phosphorylation

1 reference

based on heuristic

inferred from title

7

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23 December 2019

8

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23 December 2019

author name string

Iván Plaza-Menacho

1

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23 December 2019

Tineke van der Sluis

2

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23 December 2019

Harry Hollema

3

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23 December 2019

Oliver Gimm

4

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23 December 2019

Charles H C M Buys

5

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23 December 2019

Anthony I Magee

6

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23 December 2019

Bart J L Eggen

9

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23 December 2019

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publication date

5 January 2007

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23 December 2019

Journal of Biological Chemistry

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23 December 2019

282

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23 December 2019

9

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23 December 2019

6415-6424

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23 December 2019

GDNF family neurotrophic factor signaling: four masters, one servant?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

RET as a diagnostic and therapeutic target in sporadic and hereditary endocrine tumors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

Current concepts in RET-related genetics, signaling and therapeutics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

Central role of the threonine residue within the p+1 loop of receptor tyrosine kinase in STAT3 constitutive phosphorylation in metastatic cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

RET-familial medullary thyroid carcinoma mutants Y791F and S891A activate a Src/JAK/STAT3 pathway, independent of glial cell line-derived neurotrophic factor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

STAT signaling in the pathogenesis and treatment of leukemias

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

Serine phosphorylation and negative regulation of Stat3 by JNK

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFbeta-activated kinase 1 for STAT3 Ser-727 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

Sequential activation of Rac-1, SEK-1/MKK-4, and protein kinase Cdelta is required for interleukin-6-induced STAT3 Ser-727 phosphorylation and transactivation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

Molecular and clinical characteristics of MSH6 variants: an analysis of 25 index carriers of a germline variant

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

Cellular effects of imatinib on medullary thyroid cancer cells harboring multiple endocrine neoplasia Type 2A and 2B associated RET mutations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

Evaluation of potential mechanisms underlying genotype-phenotype correlations in multiple endocrine neoplasia type 2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

Activation of signal transducer and activator of transcription 3 by oncogenic RET/PTC (rearranged in transformation/papillary thyroid carcinoma) tyrosine kinase: roles in specific gene regulation and cellular transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

Pheochromocytoma and medullary thyroid carcinoma: a new genotype-phenotype correlation of the RET protooncogene 891 germline mutation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells

2 references

30 December 2023

https://opencitations.net/index/api/v1/citations/10.1172/JCI200522758

30 December 2023

https://opencitations.net/index/api/v1/citations/10.1172/JCI22758

Identifiers

10.1074/JBC.M608952200

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Europe PubMed Central

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23 December 2019

1 reference

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23 December 2019

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