(Q40210465)

18 September 2017

title

Does neuronal expression of GDNF effectively protect dopaminergic neurons in a rat model of Parkinson's disease? (English)

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18 September 2017

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Do Thi NA

1

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18 September 2017

Saillour P

2

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18 September 2017

Ferrero L

3

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18 September 2017

Paunio T

4

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18 September 2017

Mallet J

5

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18 September 2017

publication date

9 November 2006

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18 September 2017

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18 September 2017

volume

14

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18 September 2017

issue

5

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18 September 2017

page(s)

441-450

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The GDNF family ligands and receptors - implications for neural development

18 September 2017

cites work

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GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

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Short-term GDNF treatment provides long-term rescue of lesioned nigral dopaminergic neurons in a rat model of Parkinson's disease

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Intrastriatal glial cell line-derived neurotrophic factor promotes sprouting of spared nigrostriatal dopaminergic afferents and induces recovery of function in a rat model of Parkinson's disease.

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Sequential administration of GDNF into the substantia nigra and striatum promotes dopamine neuron survival and axonal sprouting but not striatal reinnervation or functional recovery in the partial 6-OHDA lesion model.

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Functional recovery in parkinsonian monkeys treated with GDNF

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Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain

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Localized striatal delivery of GDNF as a treatment for Parkinson disease

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Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease.

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Dopaminergic neurons protected from degeneration by GDNF gene therapy

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Behavioral and cellular protection of rat dopaminergic neurons by an adenoviral vector encoding glial cell line-derived neurotrophic factor.

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Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease

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Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system.

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Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long-lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer

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Recombinant adeno-associated viral vector (rAAV) delivery of GDNF provides protection against 6-OHDA lesion in the common marmoset monkey (Callithrix jacchus).

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Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral recovery in a primate model of Parkinson's disease.

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7 January 2021

Delivery of GDNF by an E1,E3/E4 deleted adenoviral vector and driven by a GFAP promoter prevents dopaminergic neuron degeneration in a rat model of Parkinson's disease

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7 January 2021

Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: a combined retrograde tracing and immunocytochemical study in the rat.

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Cell-type-specific and regulatable transgenesis in the adult brain: adenovirus-encoded combined transcriptional targeting and inducible transgene expression

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Dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by instrastriatal 6-hydroxydopamine in the rat

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Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum

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7 January 2021

Dopamine and glutamate agonists stimulate neuron-specific expression of Fos-like protein in the striatum

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7 January 2021

Differential effects of glial cell line-derived neurotrophic factor (GDNF) in the striatum and substantia nigra of the aged Parkinsonian rat.

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7 January 2021

Intrastriatal dopamine-rich grafts induce a hyperexpression of Fos protein when challenged with amphetamine

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7 January 2021

Changes in striatal immediate early gene expression following neonatal dopaminergic lesion and effects of intrastriatal dopaminergic transplants

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7 January 2021

Dopaminergic transplants normalize amphetamine- and apomorphine-induced Fos expression in the 6-hydroxydopamine-lesioned striatum

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7 January 2021

Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat.

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7 January 2021

Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model

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7 January 2021

Retrograde axonal transport of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggests a trophic role in the adult

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7 January 2021

Adenovirus gene transfer causes inflammation in the brain

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7 January 2021

Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302844

7 January 2021

Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302844

7 January 2021

Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferation

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302844

7 January 2021

Riluzole stimulates nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor synthesis in cultured mouse astrocytes

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302844

7 January 2021

Neuroprotection mediated by glial cell line-derived neurotrophic factor: involvement of a reduction of NMDA-induced calcium influx by the mitogen-activated protein kinase pathway.

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302844

7 January 2021

Astroglia induce neurogenesis from adult neural stem cells

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7 January 2021

Recombinational construction in Escherichia coli of infectious adenoviral genomes

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7 January 2021

An improved anion-exchange HPLC method for the detection and purification of adenoviral particles

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7 January 2021

Generation of DOPA-producing astrocytes by retroviral transduction of the human tyrosine hydroxylase gene: in vitro characterization and in vivo effects in the rat Parkinson model

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302844

7 January 2021

Direct intracerebral gene transfer of an adenoviral vector expressing tyrosine hydroxylase in a rat model of Parkinson's disease

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302844

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302844

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Dimensions Publication ID

18 September 2017

1035639193

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1 reference