(Q40211890)

18 September 2017

The role of the ubiquitin ligase E6-AP in human papillomavirus E6-mediated degradation of PDZ domain-containing proteins (English)

1 reference

18 September 2017

3

1 reference

18 September 2017

Petric Kuballa

1

1 reference

PubMed ID

17085449

18 September 2017

Konstantin Matentzoglu

series ordinal

2

1 reference

PubMed ID

17085449

18 September 2017

language of work or name

English

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publication date

3 November 2006

1 reference

Journal of Biological Chemistry

18 September 2017

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18 September 2017

282

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18 September 2017

65-71

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18 September 2017

1

1 reference

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

18 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Human papillomavirus-induced carcinogenesis and the ubiquitin-proteasome system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Papillomaviruses and cancer: from basic studies to clinical application

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Antisense targeting of E6AP elevates p53 in HPV-infected cells but not in normal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

E6AP gene suppression and characterization with in vitro selected hammerhead ribozymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Growth suppression induced by downregulation of E6-AP expression in human papillomavirus-positive cancer cell lines depends on p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

The human papillomavirus E6 protein and its contribution to malignant progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

E3-ubiquitin ligase/E6-AP links multicopy maintenance protein 7 to the ubiquitination pathway by a novel motif, the L2G box

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Human papillomavirus (HPV) E6 interactions with Bak are conserved amongst E6 proteins from high and low risk HPV types

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Role of Bak in UV-induced apoptosis in skin cancer and abrogation by HPV E6 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Recognition of unique carboxyl-terminal motifs by distinct PDZ domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

The PDZ ligand domain of the human papillomavirus type 16 E6 protein is required for E6's induction of epithelial hyperplasia in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Two distinct activities contribute to human papillomavirus 16 E6's oncogenic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Activity of the human papillomavirus E6 PDZ-binding motif correlates with an enhanced morphological transformation of immortalized human keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Chimaeric HPV E6 proteins allow dissection of the proteolytic pathways regulating different E6 cellular target proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Degradation of hDlg and MAGIs by human papillomavirus E6 is E6-AP-independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Characterization of sequence elements involved in p53 stability regulation reveals cell type dependence for p53 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Endothelial adhesion molecule ESAM binds directly to the multidomain adaptor MAGI-1 and recruits it to cell contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Human Dlg protein binds to the envelope glycoproteins of human T-cell leukemia virus type 1 and regulates envelope mediated cell-cell fusion in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

The human E6-AP gene (UBE3A) encodes three potential protein isoforms generated by differential splicing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

siRNA targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Involvement of a cellular ubiquitin-protein ligase E6AP in the ubiquitin-mediated degradation of extensive substrates of high-risk human papillomavirus E6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

c-Fos Proto-Oncoprotein Is Degraded by the Proteasome Independently of Its Own Ubiquitinylation In Vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

Ubiquitin fusion technique and related methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605117200

21 January 2018

Identifiers

DOI

10.1074/JBC.M605117200

1 reference

18 September 2017

1 reference

PubMed ID

17085449