(Q40216761)

18 September 2017

title

Human UDP-glucuronosyltransferase (UGT)1A3 enzyme conjugates chenodeoxycholic acid in the liver (English)

1 reference

(2S,3S,4S,5R,6S)-6-[(4R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid

18 September 2017

main subject

1 reference

1 reference

Jocelyn Trottier

1

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18 September 2017

Mélanie Verreault

2

1 reference

18 September 2017

Susan Grepper

3

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18 September 2017

Didier Monté

4

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18 September 2017

Julie Bélanger

5

1 reference

18 September 2017

Jenny Kaeding

6

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18 September 2017

Patrick Caron

7

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18 September 2017

Ted T Inaba

8

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18 September 2017

Olivier Barbier

9

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18 September 2017

language of work or name

English

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publication date

1 November 2006

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18 September 2017

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18 September 2017

volume

44

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18 September 2017

issue

5

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18 September 2017

page(s)

1158-1170

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https://api.unpaywall.org/v2/10.1002/hep.21362?email=unpaywall_01@example.com

18 September 2017

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26 April 2024

access restriction status

open access

1 reference

inferred from online access status

cites work

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1 reference

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21 January 2018

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Identification of a nuclear receptor for bile acids

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Bile acids: natural ligands for an orphan nuclear receptor

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Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism

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7 January 2021

The continuing importance of bile acids in liver and intestinal disease

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Hepatocellular transporters and cholestasis

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Enterohepatic transport of bile salts and genetics of cholestasis

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7 January 2021

Bile acid N-acetylglucosaminidation. In vivo and in vitro evidence for a selective conjugation reaction of 7 beta-hydroxylated bile acids in humans

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7 January 2021

Serum concentrations of bile acid glucuronides in hepatobiliary diseases

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7 January 2021

Management of primary biliary cirrhosis. The American Association for the Study of Liver Diseases practice guidelines

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7 January 2021

Bezafibrate treatment: a new medical approach for PBC patients?

1 reference

7 January 2021

Fenofibrate treatment in patients with primary biliary cirrhosis

1 reference

7 January 2021

Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily

1 reference

7 January 2021

Separation and detection of bile acid 3-glucuronides in human urine by liquid chromatography/electrospray ionization-mass spectrometry

1 reference

7 January 2021

A method for the determination of the hepatic enzyme activity catalyzing bile acid acyl glucuronide formation by high-performance liquid chromatography with pulsed amperometric detection

1 reference

7 January 2021

Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7

1 reference

7 January 2021

Inactivation of the pure antiestrogen fulvestrant and other synthetic estrogen molecules by UDP-glucuronosyltransferase 1A enzymes expressed in breast tissue

1 reference

7 January 2021

Glucuronidation of the nonsteroidal antiestrogen EM-652 (SCH 57068), by human and monkey steroid conjugating UDP-glucuronosyltransferase enzymes

1 reference

7 January 2021

Relationship between mRNA levels quantified by reverse transcription-competitive PCR and metabolic activity of CYP3A4 and CYP2E1 in human liver

1 reference

7 January 2021

FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity

1 reference

7 January 2021

Enzymatic production of bile Acid glucuronides used as analytical standards for liquid chromatography-mass spectrometry analyses

1 reference

7 January 2021

Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element

1 reference

7 January 2021

The farnesoid X receptor: a novel drug target?

1 reference

7 January 2021

Altered bile acid metabolism in primary biliary cirrhosis

1 reference

7 January 2021

Peroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzyme

1 reference

7 January 2021

Ursodeoxycholic acid-induced changes of plasma and urinary bile acids in patients with primary biliary cirrhosis

1 reference

7 January 2021

Hepatic levels of bile acids in end-stage chronic cholestatic liver disease

1 reference

7 January 2021

Coordinate regulation of hepatic bile acid oxidation and conjugation by nuclear receptors

1 reference

7 January 2021

Six novel UDP-glucuronosyltransferase (UGT1A3) polymorphisms with varying activity

1 reference

7 January 2021

Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.

1 reference

7 January 2021

Bile acids as carcinogens in human gastrointestinal cancers

1 reference

7 January 2021

Cholestasis and cholestatic syndromes

1 reference

7 January 2021

Structural basis for bile acid binding and activation of the nuclear receptor FXR

1 reference

7 January 2021

Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression.

1 reference

7 January 2021

Tissue-specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus.

1 reference

7 January 2021

Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor

1 reference

7 January 2021

Fenofibrate for patients with asymptomatic primary biliary cirrhosis

1 reference

7 January 2021

Therapeutic efficacy of decreased nitrite production by bezafibrate in patients with primary biliary cirrhosis

1 reference

7 January 2021

Identifiers

DOI

10.1002/HEP.21362

1 reference

18 September 2017

1 reference