(Q40219317)

18 September 2017

Molecular evidence-based medicine: evolution and integration of information in the genomic era. (English)

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18 September 2017

evidence-based medicine

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1

Ioannidis JP

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18 September 2017

1 May 2007

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European Journal of Clinical Investigation

18 September 2017

1 reference

18 September 2017

37

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18 September 2017

340-349

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18 September 2017

5

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Towards molecular medicine; reminiscences of the haemoglobin field, 1960-2000.

18 September 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Evidence-based medicine. A new approach to teaching the practice of medicine. Evidence-Based Medicine Working Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Evidence based medicine: what it is and what it isn't

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Users' guides to the medical literature. IX. A method for grading health care recommendations. Evidence-Based Medicine Working Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Comparison of evidence of treatment effects in randomized and nonrandomized studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Comparison of evidence on harms of medical interventions in randomized and nonrandomized studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

The mammography dilemma: a crisis for evidence-based medicine?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Is screening for breast cancer with mammography justifiable?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Systems for grading the quality of evidence and the strength of recommendations II: pilot study of a new system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

An evidence based approach to individualising treatment

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Heterogeneity of the baseline risk within patient populations of clinical trials: a proposed evaluation algorithm

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Summing up evidence: one answer is not always enough.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Shattuck lecture--medical and societal consequences of the Human Genome Project.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Welcome to the genomic era.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

A vision for the future of genomics research

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Genomic profiling to promote a healthy lifestyle: not ready for prime time

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Issues in comparisons between meta-analyses and large trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Clinical research in the United States at a crossroads: proposal for a novel public-private partnership to establish a national clinical research enterprise

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

The randomized controlled trial gets a middle-aged checkup

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Bias in clinical intervention research.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Why most published research findings are false

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Genetic associations: false or true?

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Replication validity of genetic association studies

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Mendelian disorders deserve more attention

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Computational systems biology

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Systems biology and new technologies enable predictive and preventative medicine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Concordance of functional in vitro data and epidemiological associations in complex disease genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

How frequent is altered gene expression among susceptibility genes to human complex disorders?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Surrogate end points in clinical trials: are we being misled?

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Cancer biomarkers--an invitation to the table

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Empirical evidence of design-related bias in studies of diagnostic tests

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Microarray data analysis: from disarray to consolidation and consensus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Biomedical informatics for proteomics

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Complement factor H polymorphism in age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Assessing the probability that a positive report is false: an approach for molecular epidemiology studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

A consumer's guide to subgroup analyses

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Assessing the generalizability of prognostic information

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Severe malarial anemia and cerebral malaria are associated with different tumor necrosis factor promoter alleles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Lack of association of -308A/G TNFA promoter and 196R/M TNFR2 polymorphisms with disease severity in Thai adult malaria patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Pitfalls in the use of DNA microarray data for diagnostic and prognostic classification

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

What do we mean by validating a prognostic model?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

High-resolution whole-genome association study of Parkinson disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Literature mining for the biologist: from information retrieval to biological discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Textpresso: an ontology-based information retrieval and extraction system for biological literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Data trawling: to fish or not to fish

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

The revised CONSORT statement for reporting randomized trials: explanation and elaboration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Better reporting of harms in randomized trials: an extension of the CONSORT statement

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement. Quality of Reporting of Meta-analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Minimum information about a microarray experiment (MIAME)-toward standards for microarray data

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Standards for systems biology

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Trial registration: a great idea switches from ignored to irresistible

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Empirical evidence for selective reporting of outcomes in randomized trials: comparison of protocols to published articles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Relationships fade with time: a meta-analysis of temporal trends in publication in ecology and evolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Data mining in pharmacovigilance: lessons from phantom ships.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Large upward bias in estimation of locus-specific effects from genomewide scans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Submission of microarray data to public repositories

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

ArrayExpress--a public repository for microarray gene expression data at the EBI

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Clinical trial registration: a statement from the International Committee of Medical Journal Editors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Statistical false positive or true disease pathway?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

Replicating Effects and Biases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2007.01794.X

10.1111/J.1365-2362.2007.01794.X

21 January 2018

Identifiers

DOI

1 reference

18 September 2017

1 reference

PubMed ID

17461979