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English
Bumetanide reduces seizure progression and the development of pharmacoresistant status epilepticus.
scientific article published on 11 December 2015
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
5487491
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26659482%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
title
Bumetanide reduces seizure progression and the development of pharmacoresistant status epilepticus
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
5487491
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26659482%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
main subject
status epilepticus
1 reference
based on heuristic
inferred from title
seizure
1 reference
based on heuristic
inferred from title
author
Sudhir Sivakumaran
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
5487491
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26659482%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
author name string
Jamie Maguire
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
5487491
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26659482%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
publication date
11 December 2015
1 reference
stated in
Europe PubMed Central
PMC publication ID
5487491
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26659482%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
published in
Epilepsia
1 reference
stated in
Europe PubMed Central
PMC publication ID
5487491
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26659482%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
volume
57
1 reference
stated in
Europe PubMed Central
PMC publication ID
5487491
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26659482%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
issue
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
5487491
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26659482%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
page(s)
222-232
1 reference
stated in
Europe PubMed Central
PMC publication ID
5487491
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26659482%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
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Selective activation of parvalbumin- or somatostatin-expressing interneurons triggers epileptic seizurelike activity in mouse medial entorhinal cortex
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The organic anion transport inhibitor probenecid increases brain concentrations of the NKCC1 inhibitor bumetanide
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Excitatory effects of parvalbumin-expressing interneurons maintain hippocampal epileptiform activity via synchronous afterdischarges.
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BDNF modifies hippocampal KCC2 and NKCC1 expression in a temporal lobe epilepsy model
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Disrupted Cl(-) homeostasis contributes to reductions in the inhibitory efficacy of diazepam during hyperexcited states
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Bumetanide enhances phenobarbital efficacy in a rat model of hypoxic neonatal seizures
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The extracellular space and epileptic activity in the adult brain: explaining the antiepileptic effects of furosemide and bumetanide
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Direct protein kinase C-dependent phosphorylation regulates the cell surface stability and activity of the potassium chloride cotransporter KCC2.
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Neurosteroidogenesis is required for the physiological response to stress: role of neurosteroid-sensitive GABAA receptors
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Bumetanide is not capable of terminating status epilepticus but enhances phenobarbital efficacy in different rat models
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Blood-brain barrier dysfunction can contribute to pharmacoresistance of seizures.
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20 August 2018
A novel prodrug-based strategy to increase effects of bumetanide in epilepsy
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20 August 2018
Disease-modifying effects of phenobarbital and the NKCC1 inhibitor bumetanide in the pilocarpine model of temporal lobe epilepsy
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20 August 2018
The control of kainic acid-induced status epilepticus
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20 August 2018
Sustained depolarizing shift of the GABA reversal potential by glutamate receptor activation in hippocampal neurons
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20 August 2018
Long-term expressional changes of Na+ -K+ -Cl- co-transporter 1 (NKCC1) and K+ -Cl- co-transporter 2 (KCC2) in CA1 region of hippocampus following lithium-pilocarpine induced status epilepticus (PISE).
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20 August 2018
Bumetanide enhances phenobarbital efficacy in a neonatal seizure model.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5487491
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20 August 2018
Perturbed chloride homeostasis and GABAergic signaling in human temporal lobe epilepsy.
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20 August 2018
Mice lacking P2Y2 receptors have salt-resistant hypertension and facilitated renal Na+ and water reabsorption.
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20 August 2018
KCC2-deficient mice show reduced sensitivity to diazepam, but normal alcohol-induced motor impairment, gaboxadol-induced sedation, and neurosteroid-induced hypnosis.
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20 August 2018
Trafficking of GABA(A) receptors, loss of inhibition, and a mechanism for pharmacoresistance in status epilepticus.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5487491
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20 August 2018
Predicting CNS permeability of drug molecules: comparison of neural network and support vector machine algorithms.
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20 August 2018
Early and transient increase of rat hippocampal blood-brain barrier permeability to amino acids during kainic acid-induced seizures.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5487491
retrieved
20 August 2018
Identifiers
DOI
10.1111/EPI.13270
1 reference
stated in
Europe PubMed Central
PMC publication ID
5487491
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26659482%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
PMC publication ID
5487491
1 reference
stated in
Europe PubMed Central
PMC publication ID
5487491
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26659482%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
PubMed publication ID
26659482
1 reference
stated in
Europe PubMed Central
PMC publication ID
5487491
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26659482%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
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