(Q40223264)

18 September 2017

title

A high nuclear basal level of ERK2 phosphorylation contributes to the resistance of cisplatin-resistant human ovarian cancer cells (English)

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18 September 2017

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Sooyong Lee

1

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18 September 2017

Seunghee Yoon

series ordinal

2

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18 September 2017

Dong-Hyun Kim

series ordinal

3

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18 September 2017

language of work or name

English

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publication date

4 October 2006

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18 September 2017

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18 September 2017

volume

104

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18 September 2017

issue

2

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18 September 2017

page(s)

338-344

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The MAPK signaling cascade

18 September 2017

cites work

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https://api.crossref.org/works/10.1016%2FJ.YGYNO.2006.08.040

Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

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Mammalian MAP kinase signalling cascades

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Nuclear translocation of mitogen-activated protein kinase kinase (MEK1) in response to mitogenic stimulation

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Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts

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Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer.

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A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation

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ERK1/2 is activated in non-small-cell lung cancer and associated with advanced tumours.

7 January 2021

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Inhibition of extracellular signal-regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplatin, sensitizes human ovarian cancer cell line

7 January 2021

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The MEK1 inhibitor PD98059 sensitizes C8161 melanoma cells to cisplatin-induced apoptosis

7 January 2021

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Requirement for ERK activation in cisplatin-induced apoptosis

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Increase of the resistance of human cervical carcinoma cells to cisplatin by inhibition of the MEK to ERK signaling pathway partly via enhancement of anticancer drug-induced NF kappa B activation

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Inhibition of aldose reductase enhances HeLa cell sensitivity to chemotherapeutic drugs and involves activation of extracellular signal-regulated kinases

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Ras-mediated activation of ERK by cisplatin induces cell death independently of p53 in osteosarcoma and neuroblastoma cell lines.

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Inhibition of extracellular-signal regulated kinases 1/2 is required for apoptosis of human colon cancer cells in vitro by sulindac metabolites

7 January 2021

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Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastatin-induced apoptosis

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Subcellular localization determines the protective effects of activated ERK2 against distinct apoptogenic stimuli in myeloid leukemia cells.

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Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line

7 January 2021

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Involvement of the activation loop of ERK in the detachment from cytosolic anchoring

7 January 2021

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Cisplatin-induced cell death is EGFR/src/ERK signaling dependent in mouse proximal tubule cells

7 January 2021

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Effect of extracellular signal-regulated kinase on p53 accumulation in response to cisplatin

7 January 2021

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Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury

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Phorbol 12-myristate 13-acetate inhibits death receptor-mediated apoptosis in Jurkat cells by disrupting recruitment of Fas-associated polypeptide with death domain

7 January 2021

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Cytosolic retention of phosphorylated extracellular signal-regulated kinase and a Rho-associated kinase-mediated signal impair expression of p21(Cip1/Waf1) in phorbol 12-myristate-13- acetate-induced apoptotic cells

7 January 2021

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Phorbol 12-myristate 13-acetate protects Jurkat cells from methylglyoxal-induced apoptosis by preventing c-Jun N-terminal kinase-mediated leakage of cytochrome c in an extracellular signal-regulated kinase-dependent manner

7 January 2021

1 reference

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Differential activation of ERKs to focal adhesions by PKC epsilon is required for PMA-induced adhesion and migration of human glioma cells

7 January 2021

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Involvement of the ERK signaling cascade in protein kinase C-mediated cell cycle arrest in intestinal epithelial cells

7 January 2021

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Evidence for MEK-independent pathways regulating the prolonged activation of the ERK-MAP kinases

7 January 2021

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Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

7 January 2021

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10.1016/J.YGYNO.2006.08.040

7 January 2021

Identifiers

DOI

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18 September 2017

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