(Q40226275)

18 September 2017

Removal of pattern-breaking sequences in microtubule binding repeats produces instantaneous tau aggregation and toxicity (English)

1 reference

18 September 2017

Asparouh Iliev Iliev

1

1 reference

18 September 2017

Sundar Ganesan

series ordinal

2

1 reference

18 September 2017

Gertrude Bunt

series ordinal

3

1 reference

18 September 2017

Fred Silvester Wouters

series ordinal

4

1 reference

18 September 2017

language of work or name

English

0 references

publication date

27 September 2006

1 reference

Journal of Biological Chemistry

18 September 2017

1 reference

18 September 2017

281

1 reference

18 September 2017

48

1 reference

18 September 2017

37195-37204

1 reference

Tau protein pathology in neurodegenerative diseases.

18 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Conformational change as one of the earliest alterations of tau in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Modeling tau polymerization in vitro: a review and synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Structure, stability, and aggregation of paired helical filaments from tau protein and FTDP-17 mutants probed by tryptophan scanning mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Tau aggregation is driven by a transition from random coil to beta sheet structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Formation of aberrant phosphotau fibrillar polymers in neural cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

beta-Amyloid induces paired helical filament-like tau filaments in tissue culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Distinct FTDP-17 missense mutations in tau produce tau aggregates and other pathological phenotypes in transfected CHO cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Inducible expression of Tau repeat domain in cell models of tauopathy: aggregation is toxic to cells but can be reversed by inhibitor drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Nature disfavors sequences of alternating polar and non-polar amino acids: implications for amyloidogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Atomic structure of a thermostable subdomain of HIV-1 gp41

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Neuronal injury mediated via stimulation of microglial toll-like receptor-9 (TLR9).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Chaperones increase association of tau protein with microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Calcium lability of cytoplasmic microtubules and its modulation by microtubule-associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Sequence requirements for formation of conformational variants of tau similar to those found in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Early-onset, rapidly progressive familial tauopathy with R406W mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

De novo amyloid proteins from designed combinatorial libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Sites of tau important for aggregation populate {beta}-structure and bind to microtubules and polyanions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Nonsaturable binding indicates clustering of tau on the microtubule surface in a paired helical filament-like conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Microtubule-dependent oligomerization of tau. Implications for physiological tau function and tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Conformation of paired helical filaments blocks dephosphorylation of epitopes shared with fetal tau except Ser199/202 and Ser202/Thr205.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Modeling tauopathy: a range of complementary approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Tau suppression in a neurodegenerative mouse model improves memory function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

21 January 2018

Marc Tessier-Lavigne.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

Tau and transgenic animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604863200

21 January 2018

Identifiers

DOI

10.1074/JBC.M604863200

1 reference

18 September 2017

1 reference