(Q40227606)

18 September 2017

title

Silencing mammalian target of rapamycin signaling by small interfering RNA enhances rapamycin-induced autophagy in malignant glioma cells (English)

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18 September 2017

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Iwamaru A

1

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18 September 2017

Kondo Y

2

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18 September 2017

Iwado E

3

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18 September 2017

Aoki H

4

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18 September 2017

Fujiwara K

5

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18 September 2017

Yokoyama T

6

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18 September 2017

Mills GB

7

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18 September 2017

Kondo S

8

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18 September 2017

language of work or name

English

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publication date

25 September 2006

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18 September 2017

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18 September 2017

volume

26

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18 September 2017

issue

13

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18 September 2017

page(s)

1840-1851

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Cell cycle arrest and astrocytic differentiation resulting from PTEN expression in glioma cells.

18 September 2017

cites work

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Rapamycin stimulates apoptosis of childhood acute lymphoblastic leukemia cells

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The TOR pathway: a target for cancer therapy

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Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy

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7 January 2021

Ras is involved in the negative control of autophagy through the class I PI3-kinase

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Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study

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Autophagy as a cell death and tumor suppressor mechanism

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7 January 2021

An expanding role for mTOR in cancer

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7 January 2021

Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

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7 January 2021

Targeting mTOR signaling for cancer therapy

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7 January 2021

Therapeutic efficacy of PUMA for malignant glioma cells regardless of p53 status.

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7 January 2021

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

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7 January 2021

Amino Acids and Insulin Control Autophagic Proteolysis through Different Signaling Pathways in Relation to mTOR in Isolated Rat Hepatocytes

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7 January 2021

Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3.

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7 January 2021

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

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7 January 2021

Autophagy as a regulated pathway of cellular degradation

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7 January 2021

The role of autophagy in cancer development and response to therapy.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209992

7 January 2021

Development by self-digestion: molecular mechanisms and biological functions of autophagy

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7 January 2021

Induction of autophagy and inhibition of tumorigenesis by beclin 1

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7 January 2021

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

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7 January 2021

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

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7 January 2021

Surgery for malignant gliomas: mechanistic reasoning and slippery statistics

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7 January 2021

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

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7 January 2021

Phenotypic analysis of human glioma cells expressing the MMAC1 tumor suppressor phosphatase

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7 January 2021

Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast

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Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control

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7 January 2021

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

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7 January 2021

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

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7 January 2021

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

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7 January 2021

Will mTOR inhibitors make it as cancer drugs?

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7 January 2021

Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate-1/phosphatidylinositol 3-kinase cascade.

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7 January 2021

Autophagy in health and disease: a double-edged sword

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7 January 2021

Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition.

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7 January 2021

Brain tumor survival: results from the National Cancer Data Base

1 reference

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7 January 2021

Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209992

7 January 2021

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209992

7 January 2021

PI 3-kinase, mTOR, protein synthesis and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209992

7 January 2021

Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209992

7 January 2021

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209992

7 January 2021

Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209992

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209992

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Dimensions Publication ID

18 September 2017

1023640650

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1 reference