(Q40228113)

18 September 2017

title

Activation of insulin-like growth factor type-1 receptor is required for H2O2-induced PKB phosphorylation in vascular smooth muscle cells (English)

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18 September 2017

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Zeina M Azar

1

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18 September 2017

Mohamad Z Mehdi

series ordinal

2

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18 September 2017

Ashok K Srivastava

series ordinal

3

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18 September 2017

publication date

1 July 2006

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Canadian Journal of Physiology and Pharmacology

18 September 2017

published in

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18 September 2017

volume

84

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18 September 2017

issue

7

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18 September 2017

page(s)

777-786

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Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade

18 September 2017

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Growth regulatory properties of endothelins

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Distinct roles of Ca2+, calmodulin, and protein kinase C in H2O2-induced activation of ERK1/2, p38 MAPK, and protein kinase B signaling in vascular smooth muscle cells

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The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen

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Targeting of the Akt/PKB kinase to the actin skeleton.

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Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited

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Potent inhibition of platelet-derived growth factor-induced responses in vascular smooth muscle cells by BMS-354825 (dasatinib).

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Vascular smooth muscle cell NAD(P)H oxidase activity during the development of hypertension: Effect of angiotensin II and role of insulinlike growth factor-1 receptor transactivation

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Signaling of angiotensin II-induced vascular protein synthesis in conduit and resistance arteries in vivo

21 January 2018

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Reactive oxygen species mediate Endothelin-1-induced activation of ERK1/2, PKB, and Pyk2 signaling, as well as protein synthesis, in vascular smooth muscle cells

21 January 2018

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Cellular survival: a play in three Akts

21 January 2018

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Role of oxidative stress in cardiovascular diseases

21 January 2018

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A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

21 January 2018

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Bone-metastatic potential of human prostate cancer cells correlates with Akt/PKB activation by alpha platelet-derived growth factor receptor

21 January 2018

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Free radicals in the physiological control of cell function

21 January 2018

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Protein kinase B activation by reactive oxygen species is independent of tyrosine kinase receptor phosphorylation and requires SRC activity

21 January 2018

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Oxidative stress and vascular remodelling.

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Distinct mechanisms of receptor and nonreceptor tyrosine kinase activation by reactive oxygen species in vascular smooth muscle cells: role of metalloprotease and protein kinase C-delta

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Quantitative assessment of tyrosine nitration of manganese superoxide dismutase in angiotensin II-infused rat kidney.

21 January 2018

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Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

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Modulation of G-protein expression and adenylyl cyclase signaling by high glucose in vascular smooth muscle

21 January 2018

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Characterization of two putative smooth muscle cell lines from rat thoracic aorta

21 January 2018

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Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors

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PYK2 autophosphorylation, but not kinase activity, is necessary for adhesion-induced association with c-Src, osteoclast spreading, and bone resorption

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Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor

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Reversible inactivation of the tumor suppressor PTEN by H2O2

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Redox regulation of PI 3-kinase signalling via inactivation of PTEN

21 January 2018

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Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

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Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in low-renin hypertension

21 January 2018

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Hydrogen peroxide and epidermal growth factor activate phosphatidylinositol 3-kinase and increase sodium transport in A6 cell monolayers.

21 January 2018

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H2O2-induced phosphorylation of ERK1/2 and PKB requires tyrosine kinase activity of insulin receptor and c-Src

21 January 2018

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Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo

21 January 2018

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RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner

21 January 2018

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Epidermal growth factor receptor-dependent and -independent pathways in hydrogen peroxide-induced mitogen-activated protein kinase activation in cardiomyocytes and heart fibroblasts

21 January 2018

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A role for PYK2 in ANG II-dependent regulation of the PHAS-1-eIF4E complex by multiple signaling cascades in vascular smooth muscle

21 January 2018

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21 January 2018

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C-Terminal Src Kinase (CSK) Modulates Insulin-Like Growth Factor-I Signaling through Src in 3T3-L1 Differentiation

21 January 2018

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(alpha)v(beta)3 integrins and Pyk2 mediate insulin-like growth factor I activation of Src and mitogen-activated protein kinase in 3T3-L1 cells

21 January 2018

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The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathway

21 January 2018

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Calcium-independent activation of extracellularly regulated kinases 1 and 2 by angiotensin II in hepatic C9 cells: roles of protein kinase Cdelta, Src/proline-rich tyrosine kinase 2, and epidermal growth receptor trans-activation

21 January 2018

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The activation of Akt/PKB signaling pathway and cell survival.

21 January 2018

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Mitogen-activated protein kinase activation by hydrogen peroxide is mediated through tyrosine kinase-dependent, protein kinase C-independent pathways in vascular smooth muscle cells: upregulation in spontaneously hypertensive rats

21 January 2018

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Cellular functions regulated by Src family kinases

21 January 2018

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Endothelin receptor antagonists: another potential alternative for cardiovascular diseases.

21 January 2018

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Role of endothelin in human hypertension

21 January 2018

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Expression of a functionally active gp91phox-containing neutrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries: regulation by angiotensin II.

21 January 2018

1 reference

Redox-dependent MAP kinase signaling by Ang II in vascular smooth muscle cells: role of receptor tyrosine kinase transactivation

21 January 2018

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Angiotensin II and endothelin-1 regulate MAP kinases through different redox-dependent mechanisms in human vascular smooth muscle cells

21 January 2018

1 reference

p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells

21 January 2018

1 reference

Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-d-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner

21 January 2018

1 reference

Role of Akt/protein kinase B in metabolism.

21 January 2018

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Role of NADH/NADPH oxidase-derived H2O2 in angiotensin II-induced vascular hypertrophy

21 January 2018

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Transactivation of the insulin-like growth factor-I receptor by angiotensin II mediates downstream signaling from the angiotensin II type 1 receptor to phosphatidylinositol 3-kinase

21 January 2018

1 reference

Insulin-like growth factor-1 provides protection against psychosine-induced apoptosis in cultured mouse oligodendrocyte progenitor cells using primarily the PI3K/Akt pathway

21 January 2018

1 reference

Vascular hypertrophy in angiotensin II-induced hypertension is mediated by vascular smooth muscle cell-derived H2O2.

21 January 2018

1 reference

H2O2-induced transactivation of EGF receptor requires Src and mediates ERK1/2, but not Akt, activation in renal cells

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1139/Y06-024

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18 September 2017

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