(Q40230804)

18 September 2017

Mechanical coupling via the membrane fusion SNARE protein syntaxin 1A: a molecular dynamics study (English)

1 reference

18 September 2017

Volker Knecht

1

1 reference

PMCID

1302726

18 September 2017

Helmut Grubmüller

series ordinal

2

1 reference

PMCID

1302726

18 September 2017

language of work or name

English

0 references

publication date

1 March 2003

1 reference

18 September 2017

21

1 reference

based on heuristic

inferred from page(s)

published in

Biophysical Journal

1 reference

18 September 2017

84

1 reference

18 September 2017

1527-1547

1 reference

18 September 2017

3

1 reference

Optimization by Simulated Annealing

18 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Stereochemistry of polypeptide chain configurations

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Organization of model helical peptides in lipid bilayers: insight into the behavior of single-span protein transmembrane domains

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Characterization of the thermotropic behavior and lateral organization of lipid-peptide mixtures by a combined experimental and theoretical approach: effects of hydrophobic mismatch and role of flanking residues

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Molecular determinants of exocytosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Cholesterol organization in membranes at low concentrations: effects of curvature stress and membrane thickness

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Three SNARE complexes cooperate to mediate membrane fusion

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Reconstituted syntaxin1a/SNAP25 interacts with negatively charged lipids as measured by lateral diffusion in planar supported bilayers

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

A quantitative model for membrane fusion based on low-energy intermediates

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

SNARE proteins are highly enriched in lipid rafts in PC12 cells: implications for the spatial control of exocytosis.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Structural insights into the molecular mechanism of calcium-dependent vesicle-membrane fusion

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

SNARE-mediated membrane fusion

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Protein-protein interactions in intracellular membrane fusion.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Membrane fusion and exocytosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Protein-protein interactions in neurotransmitter release

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Intracellular membrane fusion: SNAREs only?

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

SNAREpins: minimal machinery for membrane fusion

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

MOLMOL: a program for display and analysis of macromolecular structures

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

SNAP receptors implicated in vesicle targeting and fusion

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

The molecular machinery for secretion is conserved from yeast to neurons

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Vesicle fusion from yeast to man

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Bending membranes to the task: structural intermediates in bilayer fusion

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Dimerization of the synaptic vesicle protein synaptobrevin (vesicle-associated membrane protein) II depends on specific residues within the transmembrane segment.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

SNAREs and NSF in targeted membrane fusion

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Neurotransmitter release - four years of SNARE complexes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Molecular dynamics simulations of a fluid bilayer of dipalmitoylphosphatidylcholine at full hydration, constant pressure, and constant temperature

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

The transmembrane domain of syntaxin 1A is critical for cytoplasmic domain protein-protein interactions.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Calcium can disrupt the SNARE protein complex on sea urchin egg secretory vesicles without irreversibly blocking fusion.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Transmembrane helix structure, dynamics, and interactions: multi-nanosecond molecular dynamics simulations

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Distinct domains of syntaxin are required for synaptic vesicle fusion complex formation and dissociation.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Ca2+ regulates the interaction between synaptotagmin and syntaxin 1.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302726

Molecular dynamics with coupling to an external bath

20 August 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2974965-0

Lipid vesicles and membrane fusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2974965-0

Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2974965-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2974965-0

Hydrophobic mismatch between proteins and lipids in membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2974965-0

The membrane-dipped neuronal SNARE complex: a site-directed spin labeling electron paramagnetic resonance study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2974965-0

A conserved membrane-spanning amino acid motif drives homomeric and supports heteromeric assembly of presynaptic SNARE proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2974965-0

Peptide mimics of SNARE transmembrane segments drive membrane fusion depending on their conformational plasticity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2974965-0

The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2974965-0

Transmembrane orientation of hydrophobic alpha-helices is regulated both by the relationship of helix length to bilayer thickness and by the cholesterol concentration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2974965-0

Defining the functions of trans-SNARE pairs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2974965-0

Probable Inference, the Law of Succession, and Statistical Inference

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2974965-0

[Molecular dynamics of bending fluctuations in the protein secondary structures]

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12609859

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/S0006-3495(03)74965-0

1 reference

18 September 2017

1 reference

18 September 2017

1 reference

PMCID

1302726