(Q40231756)

18 September 2017

Mutant huntingtin expression induces mitochondrial calcium handling defects in clonal striatal cells: functional consequences (English)

1 reference

18 September 2017

1 reference

Tamara Milakovic

1

1 reference

18 September 2017

Rodrigo A Quintanilla

series ordinal

2

1 reference

18 September 2017

Gail V W Johnson

series ordinal

3

1 reference

18 September 2017

language of work or name

English

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publication date

13 September 2006

1 reference

Journal of Biological Chemistry

18 September 2017

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18 September 2017

281

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18 September 2017

46

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18 September 2017

34785-34795

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

18 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Loss of normal huntingtin function: new developments in Huntington's disease research

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

The ubiquitin-proteasome system in Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Mitochondrial defect in Huntington's disease caudate nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Ca(2+)-dependent permeability transition and complex I activity in lymphoblast mitochondria from normal individuals and patients with Huntington's or Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Malonate produces striatal lesions by indirect NMDA receptor activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Mitochondrial diseases in man and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Mitochondrial respiration and ATP production are significantly impaired in striatal cells expressing mutant huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Early degenerative changes in transgenic mice expressing mutant huntingtin involve dendritic abnormalities but no impairment of mitochondrial energy production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Quantitative evaluation of the effects of mitochondrial permeability transition pore modifiers on accumulation of calcium phosphate: comparison of rat liver and brain mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

L-type calcium channels reduce ROS generation in cerebellar granule cells following kainate exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Mitochondrial Ca(2+) uptake depends on the spatial and temporal profile of cytosolic Ca(2+) signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Mitochondria and Ca(2+)in cell physiology and pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Bcl-2 and mitochondrial oxygen radicals. New approaches with reactive oxygen species-sensitive probes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Mitochondrial transmembrane potential changes support the concept of mitochondrial heterogeneity during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to mitochondrial complex II inhibitor-induced cell death through a non-apoptotic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Production of reactive oxygen species by mitochondria: central role of complex III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Low stability of Huntington muscle mitochondria against Ca2+ in R6/2 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Genetic dissection of the permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Failure of exogenous NADH and cytochrome c to support energy-dependent swelling of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Cytochrome c-induced cytosolic nicotinamide adenine dinucleotide oxidation, mitochondrial permeability transition, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Porin and cytochrome oxidase containing contact sites involved in the oxidation of cytosolic NADH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Calcium, ATP, and ROS: a mitochondrial love-hate triangle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Actions of ionomycin, 4-BrA23187 and a novel electrogenic Ca2+ ionophore on mitochondria in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

The paradigm of Huntington's disease: therapeutic opportunities in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Mitochondrial and extramitochondrial apoptotic signaling pathways in cerebrocortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Interactions between mitochondrial bioenergetics and cytoplasmic calcium in cultured cerebellar granule cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Glutamate-induced deregulation of calcium homeostasis and mitochondrial dysfunction in mammalian central neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Excitotoxic injury to mitochondria isolated from cultured neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

Distinct characteristics of Ca(2+)-induced depolarization of isolated brain and liver mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603845200

21 January 2018

Identifiers

DOI

10.1074/JBC.M603845200

1 reference

18 September 2017

1 reference