(Q36259123)

13 August 2017

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title

Genetic dissection of the permeability transition pore (English)

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13 August 2017

Michael Forte

1

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PubMed ID

16167169

13 August 2017

Paolo Bernardi

series ordinal

2

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13 August 2017

1 June 2005

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Journal of Bioenergetics and Biomembranes

13 August 2017

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13 August 2017

37

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13 August 2017

3

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13 August 2017

121-128

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https://scigraph.springernature.com/pub.10.1007/s10863-005-6565-9

13 August 2017

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cites work

Recruitment of mitochondrial cyclophilin to the mitochondrial inner membrane under conditions of oxidative stress that enhance the opening of a calcium-sensitive non-specific channel

1 reference

https://api.crossref.org/works/10.1007%2FS10863-005-6565-9

Further evidence that cyclosporin A protects mitochondria from calcium overload by inhibiting a matrix peptidyl-prolyl cis-trans isomerase. Implications for the immunosuppressive and toxic effects of cyclosporin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-005-6565-9

Inhibition of Ca2(+)-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adeni

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-005-6565-9

Mitochondria and cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-005-6565-9

Cyclophilin-D promotes the mitochondrial permeability transition but has opposite effects on apoptosis and necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-005-6565-9

cDNA cloning of rat mitochondrial cyclophilin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-005-6565-9

The mitochondrial permeability transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-005-6565-9

Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperfusion of the heart.

21 January 2018

1 reference

12 December 2020

Mitochondrial permeability transition induced DNA-fragmentation in the rat hippocampus following hypoglycemia.

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12 December 2020

Flirting in little space: the ER/mitochondria Ca2+ liaison

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12 December 2020

Activity of the mitochondrial multiple conductance channel is independent of the adenine nucleotide translocator

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12 December 2020

Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore. I. Evidence for two separate Me2+ binding sites with opposing effects on the pore open probability.

1 reference

12 December 2020

Mitochondrial energy dissipation by fatty acids. Mechanisms and implications for cell death

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12 December 2020

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

1 reference

12 December 2020

Intrathecal cyclosporin prolongs survival of late-stage ALS mice

1 reference

12 December 2020

Proapoptotic BID is required for myeloid homeostasis and tumor suppression

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12 December 2020

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

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12 December 2020

Endoplasmic reticulum, Bcl-2 and Ca2+ handling in apoptosis

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12 December 2020

The mitochondrial transporter family (SLC25): physiological and pathological implications

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12 December 2020

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

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12 December 2020

Mitochondrial targeted cyclophilin D protects cells from cell death by peptidyl prolyl isomerization

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12 December 2020

Mitochondria as sensors of sphingolipids

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12 December 2020

The adenine nucleotide translocase: a central component of the mitochondrial permeability transition pore and key player in cell death.

1 reference

12 December 2020

Opening of the mitochondrial permeability transition pore causes matrix expansion and outer membrane rupture in Fas-mediated hepatic apoptosis in mice

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12 December 2020

Imaging the permeability pore transition in single mitochondria

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12 December 2020

An intrathecal bolus of cyclosporin A before injury preserves mitochondrial integrity and attenuates axonal disruption in traumatic brain injury

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12 December 2020

Endotoxin-induced mitochondrial damage correlates with impaired respiratory activity

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12 December 2020

Bad-deficient mice develop diffuse large B cell lymphoma

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12 December 2020

A mitochondrial perspective on cell death

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12 December 2020

Mitochondrial dysfunction and apoptosis in myopathic mice with collagen VI deficiency.

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12 December 2020

Mitochondria and cell death. Mechanistic aspects and methodological issues

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12 December 2020

The peptide mastoparan is a potent facilitator of the mitochondrial permeability transition

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12 December 2020

Breaking the mitochondrial barrier

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12 December 2020

The giant channel of the inner mitochondrial membrane is inhibited by cyclosporin A.

1 reference

12 December 2020

Cyclophilin-D binds strongly to complexes of the voltage-dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore

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12 December 2020

The mitochondrial permeability transition, release of cytochrome c and cell death. Correlation with the duration of pore openings in situ

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12 December 2020

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12 December 2020

Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function?

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12 December 2020

The mitochondrial benzodiazepine receptor: evidence for association with the voltage-dependent anion channel (VDAC)

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12 December 2020

A role for calcium in Bcl-2 action?

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12 December 2020

Cyclophilin D, a component of the permeability transition-pore, is an apoptosis repressor

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12 December 2020

Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence

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12 December 2020

The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.

1 reference

12 December 2020

Early resistance to cell death and to onset of the mitochondrial permeability transition during hepatocarcinogenesis with 2-acetylaminofluorene

1 reference

12 December 2020

Cyclosporin A limits calcium-induced axonal damage following traumatic brain injury

1 reference

12 December 2020

Purification and N-terminal sequencing of peptidyl-prolyl cis-trans-isomerase from rat liver mitochondrial matrix reveals the existence of a distinct mitochondrial cyclophilin

1 reference

12 December 2020

Posttreatment with the immunosuppressant cyclosporin A in transient focal ischemia.

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12 December 2020

Desensitization of the permeability transition pore by cyclosporin a prevents activation of the mitochondrial apoptotic pathway and liver damage by tumor necrosis factor-alpha

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12 December 2020

Arachidonic acid released by phospholipase A(2) activation triggers Ca(2+)-dependent apoptosis through the mitochondrial pathway

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12 December 2020

Propagation of the apoptotic signal by mitochondrial waves

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12 December 2020

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore

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12 December 2020

Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane

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12 December 2020

Mitochondrial permeability transition as a novel principle of hepatorenal toxicity in vivo

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12 December 2020

tcBid promotes Ca(2+) signal propagation to the mitochondria: control of Ca(2+) permeation through the outer mitochondrial membrane

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12 December 2020

Mitochondria are excitable organelles capable of generating and conveying electrical and calcium signals.

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12 December 2020

Changes in the bioenergetic state of rat hippocampus during 2.5 min of ischemia, and prevention of cell damage by cyclosporin A in hyperglycemic subjects.

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12 December 2020

Mitochondrial transport of cations: channels, exchangers, and permeability transition.

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12 December 2020

Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria

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12 December 2020

Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition pore.

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12 December 2020

Mitochondria and neuronal survival

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12 December 2020

Cytochrome c as an electron shuttle between the outer and inner mitochondrial membranes.

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12 December 2020

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

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12 December 2020

Mitochondrial intermembrane junctional complexes and their involvement in cell death

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12 December 2020

Pore-like and carrier-like properties of the mitochondrial aspartate/glutamate carrier after modification by SH-reagents: evidence for a preformed channel as a structural requirement of carrier-mediated transport

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12 December 2020

A large Ca2+-dependent channel formed by recombinant ADP/ATP carrier from Neurospora crassa resembles the mitochondrial permeability transition pore

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12 December 2020

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

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12 December 2020

Blockade of the mitochondrial permeability transition pore diminishes infarct size in the rat after transient middle cerebral artery occlusion

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12 December 2020

Mitochondrial permeability: dual role for the ADP/ATP translocator?

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12 December 2020

Positively charged ceramide is a potent inducer of mitochondrial permeabilization.

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12 December 2020

Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase

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12 December 2020

Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death.

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12 December 2020

Mitochondrial calcium homeostasis: mechanisms and molecules.

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12 December 2020

Inhibition of the mitochondrial permeability transition by cyclosporin A during long time frame experiments: relationship between pore opening and the activity of mitochondrial phospholipases.

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12 December 2020

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

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12 December 2020

Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress

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12 December 2020

A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis

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12 December 2020

Mechanisms of cytochrome c release by proapoptotic BCL-2 family members

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12 December 2020

Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury

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12 December 2020

The mitochondrion in apoptosis: how Pandora's box opens

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12 December 2020

Protection by Cyclosporin A of ischemia/reperfusion-induced damage in isolated rat hearts.

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12 December 2020

Amelioration by cyclosporin A of brain damage following 5 or 10 min of ischemia in rats subjected to preischemic hyperglycemia.

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12 December 2020

Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore, and cyclosporin A-sensitive channel.

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12 December 2020

The permeability transition pore complex: another view.

1 reference

12 December 2020

10.1007/S10863-005-6565-9

Identifiers

DOI

1 reference

13 August 2017

1 reference

PubMed ID

16167169