(Q44859595)

English

An intrathecal bolus of cyclosporin A before injury preserves mitochondrial integrity and attenuates axonal disruption in traumatic brain injury

scientific article published in April 1999

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scholarly article

1 reference

Europe PubMed Central

6 December 2017

An intrathecal bolus of cyclosporin A before injury preserves mitochondrial integrity and attenuates axonal disruption in traumatic brain injury (English)

1 reference

Europe PubMed Central

6 December 2017

traumatic brain injury

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1 reference

based on heuristic

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author name string

Okonkwo DO

1

1 reference

Europe PubMed Central

6 December 2017

Povlishock JT

2

1 reference

Europe PubMed Central

6 December 2017

publication date

1 April 1999

1 reference

Europe PubMed Central

6 December 2017

Journal of Cerebral Blood Flow & Metabolism

1 reference

Europe PubMed Central

6 December 2017

19

1 reference

Europe PubMed Central

6 December 2017

4

1 reference

Europe PubMed Central

6 December 2017

443-451

1 reference

Europe PubMed Central

6 December 2017

https://scigraph.springernature.com/pub.10.1097/00004647-199904000-00010

0 references

Diffuse axonal injury due to nonmissile head injury in humans: an analysis of 45 cases.

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Permeability of the blood-brain barrier to the immunosuppressive cyclic peptide cyclosporin A.

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Only in the presence of immunophilins can cyclosporin and FK506 disrupt in vivo binding of calcineurin A to its autoinhibitory domain yet strengthen interaction between calcineurin A and B subunits

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Apoptotic morphology of dentate gyrus granule cells following experimental cortical impact injury in rats: possible role in spatial memory deficits

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Delayed, selective neuronal death following experimental cortical impact injury in rats: possible role in memory deficits.

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

The immunophilins, FK506 binding protein and cyclophilin, are discretely localized in the brain: relationship to calcineurin

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

On the involvement of a cyclosporin A sensitive mitochondrial pore in myocardial reperfusion injury

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Changes in the bioenergetic state of rat hippocampus during 2.5 min of ischemia, and prevention of cell damage by cyclosporin A in hyperglycemic subjects.

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

FK506 and the role of immunophilins in nerve regeneration

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Mechanisms by which mitochondria transport calcium

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Inhibition of Ca2(+)-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adeni

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Amelioration by cyclosporin A of brain damage following 5 or 10 min of ischemia in rats subjected to preischemic hyperglycemia.

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Mechanism of calcium entry during axon injury and degeneration

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

A new model of diffuse brain injury in rats. Part I: Pathophysiology and biomechanics

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

A mechanistic analysis of nondisruptive axonal injury: a review

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Implication of mitochondria in apoptosis.

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Characterization of a distinct set of intra-axonal ultrastructural changes associated with traumatically induced alteration in axolemmal permeability

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Are the pathobiological changes evoked by traumatic brain injury immediate and irreversible?

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Vascular permeability alterations to horseradish peroxidase in experimental brain injury

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Neural roles of immunophilins and their ligands

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

The mechanism of action of cyclosporin A and FK506

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Cyclosporin A protects against ischemia-reperfusion injury in the brain

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

High brain densities of the immunophilin FKBP colocalized with calcineurin

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat.

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Anoxic injury of rat optic nerve: ultrastructural evidence for coupling between Na+ influx and Ca(2+)-mediated injury in myelinated CNS axons.

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury.

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Amelioration of mitochondrial function by a novel antioxidant U-101033E following traumatic brain injury in rats.

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

The mitochondrial permeability transition.

1 reference

https://api.crossref.org/works/10.1097%2F00004647-199904000-00010

21 January 2018

Identifiers

10.1097/00004647-199904000-00010

1 reference

Europe PubMed Central

6 December 2017

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0 references

1 reference

Europe PubMed Central

6 December 2017

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