(Q41659803)

6 October 2017

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title

Neural roles of immunophilins and their ligands (English)

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6 October 2017

1

D M Sabatini

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6 October 2017

M M Lai

2

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PubMed ID

9396011

6 October 2017

S H Snyder

series ordinal

3

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6 October 2017

1 October 1997

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6 October 2017

Molecular Neurobiology

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6 October 2017

15

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6 October 2017

223-239

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6 October 2017

2

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https://scigraph.springernature.com/pub.10.1007/bf02740635

6 October 2017

0 references

cites work

Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location

1 reference

https://api.crossref.org/works/10.1007%2FBF02740635

FAP48, a new protein that forms specific complexes with both immunophilins FKBP59 and FKBP12. Prevention by the immunosuppressant drugs FK506 and rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02740635

Correlation between dynamics and high affinity binding in an SH2 domain interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02740635

Tacrolimus (FK506) ameliorates skilled motor deficits produced by middle cerebral artery occlusion in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02740635

Structure-function relationships in the FK506-binding protein (FKBP) family of peptidylprolyl cis-trans isomerases

21 January 2018

1 reference

12 December 2020

The function of dynamin in endocytosis

1 reference

12 December 2020

Immunophilins and the nervous system

1 reference

12 December 2020

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

1 reference

12 December 2020

Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

1 reference

12 December 2020

A novel genetic system to detect protein-protein interactions

1 reference

12 December 2020

Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models

1 reference

12 December 2020

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

1 reference

12 December 2020

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

1 reference

12 December 2020

FK 506 and rapamycin: molecular probes of T-lymphocyte activation

1 reference

12 December 2020

Nitric oxide synthase regulatory sites. Phosphorylation by cyclic AMP-dependent protein kinase, protein kinase C, and calcium/calmodulin protein kinase; identification of flavin and calmodulin binding sites

1 reference

12 December 2020

Peptidyl-prolyl cis-trans isomerases, cyclophilin, FK506-binding protein, and ninaA: four of a kind

1 reference

12 December 2020

Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia

1 reference

12 December 2020

The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin

1 reference

12 December 2020

Effect of cyclosporin A on lymphocyte activation by the calcium ionophore A23187

1 reference

12 December 2020

Probing Immunosuppressant Action with a Nonnatural Immunophilin Ligand

1 reference

12 December 2020

The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors.

1 reference

12 December 2020

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1 reference

12 December 2020

Cyclophilin: a specific cytosolic binding protein for cyclosporin A

1 reference

12 December 2020

Immunophilins in protein folding and immunosuppression.

1 reference

12 December 2020

Relationship of the ataxia-telangiectasia protein ATM to phosphoinositide 3-kinase

1 reference

12 December 2020

4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase

1 reference

12 December 2020

Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells

1 reference

12 December 2020

Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12

1 reference

12 December 2020

The immunosuppressive macrolides FK-506 and rapamycin act as reciprocal antagonists in murine T cells.

1 reference

12 December 2020

Identification of a gephyrin binding motif on the glycine receptor beta subunit

1 reference

12 December 2020

High brain densities of the immunophilin FKBP colocalized with calcineurin

1 reference

12 December 2020

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

1 reference

12 December 2020

Immunophilin regulation of neurotransmitter release

1 reference

12 December 2020

The dynamins: redundant or distinct functions for an expanding family of related GTPases?

1 reference

12 December 2020

Molecular mechanisms in synaptic vesicle endocytosis and recycling

1 reference

12 December 2020

Liver transplantation (2).

1 reference

12 December 2020

Rapamycin (AY-22,989), a new antifungal antibiotic. III. In vitro and in vivo evaluation

1 reference

12 December 2020

Biological effects of cyclosporin A: A new antilymphocytic agent

1 reference

12 December 2020

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

1 reference

12 December 2020

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

12 December 2020

Neurotransmitter release regulated by nitric oxide in PC-12 cells and brain synaptosomes

1 reference

12 December 2020

Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein

1 reference

12 December 2020

Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity

1 reference

12 December 2020

Control of p70 s6 kinase by kinase activity of FRAP in vivo

1 reference

12 December 2020

Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins

1 reference

12 December 2020

Liver transplantation (1).

1 reference

12 December 2020

Calcineurin-mediated protein dephosphorylation in brain nerve terminals regulates the release of glutamate

1 reference

12 December 2020

The immunosuppressant FK506 increases the rate of axonal regeneration in rat sciatic nerve

1 reference

12 December 2020

Efficacy and mechanism of action of rapamycin in presensitized recipients of experimental allografts

1 reference

12 December 2020

Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: one in the presence and one in the absence of CsA

1 reference

12 December 2020

Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycin

1 reference

12 December 2020

Immunosuppressant FK506 promotes neurite outgrowth in cultures of PC12 cells and sensory ganglia

1 reference

12 December 2020

Glutamate neurotoxicity and diseases of the nervous system

1 reference

12 December 2020

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

1 reference

12 December 2020

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

1 reference

12 December 2020

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

1 reference

12 December 2020

Calcineurin inhibition of dynamin I GTPase activity coupled to nerve terminal depolarization

1 reference

12 December 2020

Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A

1 reference

12 December 2020

Immunophilin FK506 binding protein associated with inositol 1,4,5-trisphosphate receptor modulates calcium flux

1 reference

12 December 2020

A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

1 reference

12 December 2020

RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex

1 reference

12 December 2020

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

1 reference

12 December 2020

Association of protein kinase A and protein phosphatase 2B with a common anchoring protein

1 reference

12 December 2020

Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein

1 reference

12 December 2020

Cellular functions of immunophilins

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12 December 2020

Neuronal regeneration enhances the expression of the immunophilin FKBP-12

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12 December 2020

Purified inositol 1,4,5-trisphosphate receptor mediates calcium flux in reconstituted lipid vesicles

1 reference

12 December 2020

Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice

1 reference

12 December 2020

The immunosuppressant FK506 increases functional recovery and nerve regeneration following peripheral nerve injury

1 reference

12 December 2020

Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

1 reference

12 December 2020

FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domain

1 reference

12 December 2020

Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation

1 reference

12 December 2020

The effect of cyclosporine on the use of hospital resources for kidney transplantation.

1 reference

12 December 2020

Sequence analysis of the ryanodine receptor: possible association with a 12K, FK506-binding immunophilin/protein kinase C inhibitor

1 reference

12 December 2020

Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

1 reference

12 December 2020

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

1 reference

12 December 2020

Bench to bedside: the glutamate connection

1 reference

12 December 2020

FK506 binding protein associated with the calcium release channel (ryanodine receptor)

1 reference

12 December 2020

The mechanism of action of cyclosporin A and FK506

1 reference

12 December 2020

Mechanism of activation of the TGF-beta receptor

1 reference

12 December 2020

TGF-beta receptors and actions

1 reference

12 December 2020

Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues

1 reference

12 December 2020

Solubilization, purification, and characterization of an inositol trisphosphate receptor.

1 reference

12 December 2020

The immunophilins, FK506 binding protein and cyclophilin, are discretely localized in the brain: relationship to calcineurin

1 reference

12 December 2020

Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux

1 reference

12 December 2020

Regulation of translation elongation factor-2 by insulin via a rapamycin-sensitive signalling pathway

1 reference

12 December 2020

The stimulation of the phosphorylation of ribosomal protein S6 by cycloheximide and puromycin

1 reference

12 December 2020

Complementary DNA encoding the human T-cell FK506-binding protein, a peptidylprolyl cis-trans isomerase distinct from cyclophilin

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02740635

1 reference

PubMed ID

9396011

Dimensions Publication ID

6 October 2017

0 references

1 reference

PubMed ID

9396011