(Q40237882)

18 September 2017

Abl tyrosine kinase regulates endocytosis of the epidermal growth factor receptor (English)

1 reference

18 September 2017

Barbara Tanos

1

1 reference

PubMed ID

16943190

18 September 2017

Ann Marie Pendergast

series ordinal

2

1 reference

PubMed ID

16943190

18 September 2017

language of work or name

English

0 references

publication date

29 August 2006

1 reference

Journal of Biological Chemistry

18 September 2017

1 reference

18 September 2017

281

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18 September 2017

32714-32723

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18 September 2017

43

1 reference

Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases

18 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Control of EGF receptor signaling by clathrin-mediated endocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

21 January 2018

Endocytosis and cancer.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Grb2 regulates internalization of EGF receptors through clathrin-coated pits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

A single amino acid substitution in v-erbB confers a thermolabile phenotype to ts167 avian erythroblastosis virus-transformed erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Activated Cdc42 Sequesters c-Cbl and Prevents EGF Receptor Degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

The Abl family kinases: mechanisms of regulation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

A quantitative protein interaction network for the ErbB receptors using protein microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Activation of Abl tyrosine kinases promotes invasion of aggressive breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Comparative tyrosine-kinase profiles in colorectal cancers: enhanced arg expression in carcinoma as compared with adenoma and normal mucosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Expression profiling of microdissected pancreatic adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Renal medullary carcinoma and ABL gene amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Abl tyrosine kinases are required for infection by Shigella flexneri

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Bidirectional signaling links the Abelson kinases to the platelet-derived growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

An intramolecular SH3-domain interaction regulates c-Abl activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Mechanisms controlling EGF receptor endocytosis and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Src promotes destruction of c-Cbl: implications for oncogenic synergy between Src and growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Autophosphorylation sites on the epidermal growth factor receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras-Shc-Grb2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Negative receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Epidermal growth factor receptor activation under oxidative stress fails to promote c-Cbl mediated down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

HPV16 E5 protein disrupts the c-Cbl-EGFR interaction and EGFR ubiquitination in human foreskin keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Expression of constitutively activated EGFRvIII in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Regulation of signal transduction by endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

Escape from Cbl-mediated downregulation: a recurrent theme for oncogenic deregulation of receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603126200

21 January 2018

Identifiers

DOI

10.1074/JBC.M603126200

1 reference

18 September 2017

1 reference

PubMed ID

16943190